Results 131 to 140 of about 654,528 (315)
s-Allyl Cysteine, s-Ethyl Cysteine and s-Propyl Cysteine Alleviate beta-Amyloid, Glycative and Oxidative Injury in Brain of Mice Treated by D-galactose [PDF]
, 2012 [[abstract]]The neuro-protective effects of s-allyl cysteine, s-ethyl cysteine and s-propyl cysteine inD-galactose (DG) treated mice were examined. DG treatment increased the formation ofA1-40 and A1-42, and enhanced mRNA expression of -amyloid precursor
SHIH-JEI TSAI;C. PERRY CHIU;HUI-TING YANG;MEI-CHIN YIN
core
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
Advanced Healthcare Materials, EarlyView.An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses
Advanced Healthcare Materials, EarlyView.This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang +16 more
wiley +1 more source
Cysteine-cystine redox cycling in a gold-gold dual-plate generator-collector microtrench sensor [PDF]
, 2014 Thiols and disulfides are ubiquitous and important analytical targets. However, their redox properties, in particular on gold sensor electrodes, are complex and obscured by strong adsorption. Here, a gold-gold dual-plate microtrench dual-electrode sensor
P Estrela (21829580) +8 more
core
Cysteine-reactive free ISG15 generates IL-1β-producing CD8α+ dendritic cells at the site of infection [PDF]
, 2020 IFN-stimulated gene (ISG) 15 is a ubiquitin-like protein induced after type I IFN stimulation. There is a dearth of in vivo models to study free unconjugated ISG15 function.
Annabel Borg (9332051) +10 more
core
Advanced Healthcare Materials, EarlyView.Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Cysteine-Mediated Etching of Gold Nanorods by Ferric Ions: Probing Cys Spatial Distribution Features on a Rod Surface [PDF]
Modulating the interaction of chiral molecules with achiral plasmonic nanostructures/superstructures is an important means to realize the transfer of molecular chirality to plasmonic chirality. Especially, adsorption features of chiral molecules, such as
Xiaochun Wu (86470) +5 more
core +1 more source
Structural Guidance in 3D Microgel‐in‐Hydrogel Systems to Improve Chondrogenesis
Advanced Healthcare Materials, EarlyView.The Anisogel, an anisotropic microgel‐in‐hydrogel system, guides chondrogenic differentiation of human mesenchymal stromal cells (hMSCs) modulated by the alignment and size of anisometric microgels. Chondrogenic markers are upregulated in an in vitro model and guided tissue infiltration is enhanced in a semi‐orthopedic mouse model due to the physico ...
Julia Kamp +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco +7 more
wiley +1 more source