Results 101 to 110 of about 654,528 (315)

Decoding the role of cysteine metabolism in angiogenesis [PDF]

reservedAngiogenesis is the process by which new blood vessels are formed from pre existing ones in response to signals triggered by pathophysiological conditions, such as wound healing or cancer. In this study, we aim to decode the role of cysteine in
ANDREUZZA, SEBASTIANO
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Methyl Jasmonate and Salicylic Acid Induced Oxidative Stress and Accumulation of Phenolics in Panax ginseng Bioreactor Root Suspension Cultures

Molecules, 2007
To investigate the enzyme variations responsible for the synthesis of phenolics, 40 day-old adventitious roots of Panax ginseng were treated with 200 μM methyl jasmonate (MJ) or salicylic acid (SA) in a 5 L bioreactor suspension culture (working ...
Kee-Yoeup Paek, Eun-Joo Hahn, Mohammad Babar Ali   +2 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

The proteins of Fusobacterium spp. involved in hydrogen sulfide production from L-cysteine [PDF]

, 2017
Background: Hydrogen sulfide (H2S) is a toxic foul-smelling gas produced by subgingival biofilms in patients with periodontal disease and is suggested to be part of the pathogenesis of the disease.
Gunnar Dahlén, Gunnel Svensäter, Basic, Amina, Dahlen, Gunnar, Madeleine Blomqvist (3834589), Amina Basic (3834592), Svensäter, Gunnel,, Amina Basic, Madeleine Blomqvist, Blomqvist, Madeleine,, Gunnel Svensäter (585787), Blomqvist, Madeleine, Svensäter, Gunnel, Malmö University., Gunnar Dahlén (3834586), Dahlen, Gunnar,, Basic, Amina,   +16 more
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Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Cysteine-independent inhibition of alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT) [PDF]

, 2018
Alzheimer's disease (AD) is a tauopathy characterised by pathological fibrillisation of tau protein to form the paired helical filaments (PHFs) which constitute neurofibrillary tangles.
Janet E Rickard (16247804), Louise Serpell (4461124), Michael Simpson (2990385), Thomas Baddeley (16268486), John M D Storey (16247807), Saskia Pollack (4463047), Charles R Harrington (16247810), Ana Raulin (4466113), Youssra Al-Hilaly (4462402), Claude M Wischik (16247813), Pascale Schellenberger (220679)   +10 more
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The Reaction of Aminonitriles with Aminothiols: A Way to Thiol-Containing Peptides and Nitrogen Heterocycles in the Primitive Earth Ocean

Life, 2018
The Strecker reaction of aldehydes with ammonia and hydrogen cyanide first leads to α-aminonitriles, which are then hydrolyzed to α-amino acids.
Ibrahim Shalayel, Seydou Coulibaly, Kieu Dung Ly, Anne Milet, Yannick Vallée   +4 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Role of N-glycans and cysteine residues in the assembly of homotrimeric P2X1 receptors [PDF]

, 2003
P2X receptor subunits assemble in the ER of Xenopus oocytes to homomultimeric or heteromultimeric complexes that appear as ATP-gated cation channels at the cell surface. In this work it was intended to investigate the posttranslational modifications such
Aschrafi, Sepandarmaz
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