Results 101 to 110 of about 695,646 (296)
Cysteine-cystine redox cycling in a gold-gold dual-plate generator-collector microtrench sensor [PDF]
, 2014 Thiols and disulfides are ubiquitous and important analytical targets. However, their redox properties, in particular on gold sensor electrodes, are complex and obscured by strong adsorption. Here, a gold-gold dual-plate microtrench dual-electrode sensor
P Estrela (21829580) +8 more
core +3 more sources
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source
, 2011 Panel : HT-29 cells were cultured with vehicle (), 2 mM -cysteine (), 10 μM DATS () or both 10 μM DATS and 2 mM -cysteine () for 12 h. The microtubule distribution of the cells was assessed by the immunofluorescence method using anti-β-tubulin antibody ...
Isao Hasegawa (52806) +8 more
core +1 more source
, 2012 The sulfur amino acid, cysteine plays an essential role in maintaining cellular redox potential and is a key constituent of the antioxidant, glutathione.
McBean, Gethin J.
core +1 more source
H2S-Mediated Protein S-Sulfhydration: A Prediction for Its Formation and Regulation
Molecules, 2017 Protein S-sulfhydration is a newly discovered post-translational modification of specific cysteine residue(s) in target proteins, which is involved in a broad range of cellular functions and metabolic pathways.
Youngjun Ju +4 more
doaj +1 more source
Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Advanced Healthcare Materials, EarlyView.Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi +2 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão +5 more
wiley +1 more source
Advanced Materials, EarlyView.Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song +14 more
wiley +1 more source
Role of N-glycans and cysteine residues in the assembly of homotrimeric P2X1 receptors [PDF]
, 2003 P2X receptor subunits assemble in the ER of Xenopus oocytes to homomultimeric or heteromultimeric complexes that appear as ATP-gated cation channels at the cell surface. In this work it was intended to investigate the posttranslational modifications such
Aschrafi, Sepandarmaz
core
Cysteine-Modified Self-Assembling Peptides on Gold: The Role of the Head and Tail
, 2019 Molecular self-assembly consists of the spontaneous aggregation of molecules into a well-defined structure guided by noncovalent bonds. The self-assembly strategy is ubiquitous in nature and recently has been proposed as a nature-mimetic strategy in ...
Giovanna Iucci (794226) +6 more
core +1 more source