Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]
, 2013 Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F. +11 more
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Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB [PDF]
, 2013 Cysteine proteases of the papain superfamily are present in nearly all eukaryotes. They play pivotal roles in the biology of parasites and inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping
Mottram, Jeremy C +5 more
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Neurobiology of Disease, 2021 Parkinson's disease (PD) is one of the most common neurodegenerative diseases, which is characterized by the loss of dopaminergic neurons in the nigrostriatal pathway.
Li Zou +13 more
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Cysteine proteinases of microorganisms and viruses [PDF]
Biochemistry (Moscow), 2008 This review considers properties of secreted cysteine proteinases of protozoa, bacteria, and viruses and presents information on the contemporary taxonomy of cysteine proteinases. Literature data on the structure and physicochemical and enzymatic properties of these enzymes are reviewed.
Rudenskaya, G. N., Pupov, D. V.
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Transcriptional silencing of multiple genes in trophozoites of Entamoeba histolytica. [PDF]
PLoS Pathogens, 2006 In a previous work we described the transcriptional silencing of the amoebapore A (AP-A) gene (Ehap-a) of Entamoeba histolytica strain HM-1:IMSS. The silencing occurred following transfection with a plasmid containing a 5' upstream region (473 bp) of ...
Rivka Bracha +3 more
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Programmed Cell Death Progresses Differentially in Epidermal and Mesophyll Cells of Lily Petals. [PDF]
PLoS ONE, 2015 In the petals of some species of flowers, programmed cell death (PCD) begins earlier in mesophyll cells than in epidermal cells. However, PCD progression in each cell type has not been characterized in detail.
Hiroko Mochizuki-Kawai +3 more
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Cystatins — Inhibitors of Cysteine Proteinases [PDF]
Critical Reviews in Oral Biology & Medicine, 1992 The cystatin superfamily of proteins, derived from a common ancestor, is comprised of a diverse group of potent cysteine proteinase inhibitors and antibacterial/viral agents grouped into several families. This review concentrates on family 2 cystatins, namely, the human salivary cystatins and cystatin C.
L A, Bobek, M J, Levine
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BMC Plant Biology, 2012 Background Cysteine proteinases perform multiple functions in seeds, including participation in remodelling polypeptides and recycling amino acids during maturation and germination.
Lepelley Maud +5 more
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"Comparison of Adult Somatic and Cysteine Proteinas Antigens of Fasciola gigantica in Enzyme Linked Immunosorbent Assay for Serodiagnosis of Human Fasciolosis" [PDF]
Iranian Journal of Public Health, 2002 Fasciolosis caused by Fasciola hepatica and F.gigantica is one of the major public health problems in the world and in Iran. Considering that stool examination for Fasciola eggs is not a sensitive method and only 25% of infected patients pass the eggs in
MB Rokni, J Massoud, JP Dalton
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Protective effect of latex proteins from Plumeria pudica against acetaminophen-induced acute liver injury [PDF]
Anais da Academia Brasileira de CiênciasThe protein fraction from Plumeria pudica latex (LPPp) was evaluated against APAP-induced liver injury in mice. Key measurements included total leukocyte count, liver weight, AST, ALT, liver levels of MDA, GSH, SOD, MPO, NO3/NO2 concentration, cytokines ...
BRUNA DA SILVA SOUZA +20 more
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