Results 181 to 190 of about 778,605 (292)

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source

Smolstatin1, a unique cystatin-like stefin of <i>Sphaerospora molnari</i>, is essential for parasite development. [PDF]

Curr Res Microb Sci
Bartošová-Sojková P, Dobai T, Kyslík J, Havlíčková P, Vancová M, Picard-Sánchez MA, Qadiri SSN, Martins LA, Urbanová V, Kosakyan A, Bílý T, Kale D, Kotál J, Chan JTH, Korytář T, Ludwig J, Smatanová IK, Holzer AS, Sojka D.   +18 more
europepmc   +1 more source

Metabolic‐Redox Remodeling of Inflammatory Synovium by Mannose‐Modified Selenium Nanoparticles for Osteoarthritis Therapy

Advanced Science, EarlyView.
Elevated GLUT1‐driven glycolysis and disrupted selenoprotein‐dependent redox homeostasis drive osteoarthritic progression. Intra‐articular mannose‐modified selenium nanoparticles (M‐SeNPs) selectively target hypermetabolic synovial cells to reprogram aberrant glycolysis and restore endogenous antioxidant defenses.
Yu‐Qing Zou, Chen‐Hao Xu, Bo‐Wei Li, Leung Chan, Yi‐Di Xu, Han‐Bo Su, Rui Peng, Fang‐Ji Luo, Ya‐Chen Peng, Zhen‐Yan Li, Vincent Kam Wai Wong, Xiao‐Fei Zheng, Xing Ma, Zhen‐Gang Zha, Tianfeng Chen, Huan‐Tian Zhang   +15 more
wiley   +1 more source

Qualitative and Quantitative Proteomic Analysis of Venoms from Mexican Rattlesnakes. [PDF]

Toxins (Basel)
Hernández-Ancheyta L, Reynoso VH, López-Vidal JC, Hernández-Sánchez J, Delgadillo-Gutiérrez K, Domínguez-López ML, Luna-Herrera J.   +6 more
europepmc   +1 more source

Computational investigation of potential natural compounds as inhibitors of monkeypox virus cysteine proteinase. [PDF]

Front Bioinform
Nalwa R, Chaudhary AA, Chouhan M, Tiwari PK, Gupta S, Rudayni HA, Dwivedi VD, Kumar S.   +7 more
europepmc   +1 more source

Helminth-derived stefin-1 selectively reduces leukemic cell viability and promotes apoptosis in U937 cells. [PDF]

PLoS One
Ploensil P, Suwanwong Y, Phannasil P, Tarasuk M, Thonsri U, Prapasitsin P, Martviset P, Chantree P.   +7 more
europepmc   +1 more source

[Cysteine proteinases and their endogenous inhibitors].

Postepy biochemii, 1989
G, Korzus, B, Turyna
openaire   +1 more source

The Concentration of Leukocyte Elastase-alpha1-Proteinase Inhibitor Complex in Bronchoalveolar Lavage Fluid from Healthy Human Subjects [PDF]

, 1985
Boudier, C., Bieth, J. G., Pelletier, A., Pauli, G., Jochum, Marianne   +4 more
core   +1 more source

In Silico and In Vitro Screening and Mechanisms of Angiotensin I-Converting Enzyme Inhibitory Peptides from Protein Hydrolysates of Royal Jelly. [PDF]

Foods
Zhang Y, Guo S, Miao H, Gu Y, Zhang J.
europepmc   +1 more source

Click‐to‐Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds

Angewandte Chemie International Edition, EarlyView.
Click chemistry has evolved from making covalent connections to also breaking bonds. Here, a cascade assembly is reported that combines these maneuvers to build multifunctional biomolecular scaffolds in a modular one‐pot reaction. The unifying azide release‐tetrazine hub clicks with a trans‐cyclooctene tag, rapidly liberates N,N‐dimethylaniline to ...
Markus Staudt, Christian B. M. Poulie, Andreas Löffler, Peter R. Meinig, Riley J. Deutsch‐Williams, Barbara Herrmann, Ralph Weissleder, Hannes Mikula, Jonathan C. T. Carlson, Matthias M. Herth   +9 more
wiley   +1 more source