Results 221 to 230 of about 778,605 (292)

Oncometabolite fumarate impairs ATR-CHK1 signaling by succinating RPA1 in fumarate hydratase-deficient renal cell carcinoma cells. [PDF]

Cancer Metab
Liu N, Shen C, Zhou T, Zhou Y, Yuan H, Bi H, Wang Y, Pei X, Su R, Trisal V, Zheng L, Shi Y, Shen B.   +12 more
europepmc   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

The pivotal role of β-lactone stereochemistry in the development of SARS-CoV-2 M^pro inhibitors. [PDF]

Protein Sci
Świderek K, Moliner V.
europepmc   +1 more source

Stage‐Dependent Metabolic Reprogramming Drives a Self‐Organizing Microbial Network During Shanxi Aged Vinegar

Food Bioengineering, EarlyView.
Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu, Jing Liu, Dantong Liu, Menglei Xia, Jia Song, Yu Zheng, Min Wang   +6 more
wiley   +1 more source

Cathepsin Family Proteases in Prodrug Design: Recent Advances. [PDF]

ChemMedChem
Liu H, Zheng M, Ng CS, Loh TP.
europepmc   +1 more source

Mining Oral Probiotics Based on Their Pathogen Inhibition and Deodorization Roles

Food Bioengineering, EarlyView.
A promising oral probiotic strain Streptococcus salivarius MY‐6 stood out from 41 candidate lactic acid bacteria through the high‐throughput strategy based on its inhibitions of the growth and biofilm formation of the main oral pathogens Fusobacterium nucleatum and Porphyromonas gingivalis, as well as its elimination of oral malodor‐associated ...
Yaao Chen, Xiaofeng Xu, Yang Long, Deyi Yin, Haohao Sheng, Lei Du, Minxi Wan, Li Zhao, Jingli Xie   +8 more
wiley   +1 more source

Integrated Venom Gland Transcriptomic and Venom Proteomic Analyses of the Digger Wasp <i>Cerceris japonica</i>. [PDF]

Toxins (Basel)
Kazuma K, Tani N, Konno K, Kawaguchi M, Inagaki H.   +4 more
europepmc   +1 more source

Microbial Interventions in Processing of Plant Based Proteins: Unlocking Extraction Dynamics and Functionality for Human Health

Food Bioengineering, EarlyView.
Fermentation enhances nutritional & techno‐functional properties of plant protein. Three distinct stages of fermentation impact on different aspects of plant protein. Fermentation induces flavors modulation through new organic compounds formation. Plant protein fermentation improves their utility in food applications.
Disha, Mitali Madhumita, Dharmender Kumar, Pramod Kumar Prabhakar   +3 more
wiley   +1 more source

Synthesis of New Asymmetrical Chalcones and Evaluation of Their Use in Combination with Curcumin Against Rhodesain of <i>T. brucei rhodesiense</i>. [PDF]

Int J Mol Sci
Di Chio C, Starvaggi J, Natale B, Previti S, De Luca F, Cosconati S, Schirmeister T, Zappalà M, Ettari R.   +8 more
europepmc   +1 more source

Mango Seed Valorization: Sustainable Source of Nutrients, Bioactives, and Value‐Added Applications

Food Chemistry International, EarlyView.
Highlighting mango seed as a valuable yet overlooked by‐product, promoting its utilization and reducing agroindustrial waste. ABSTRACT Mango (Mangifera indica L.) is one of the most widely cultivated tropical fruits, generating large quantities of by‐products during processing, with mango seed representing 20%–25% of the whole fruit weight ...
Priyanka Yadav, Mazia Ahmed, Unaiza Iqbal, Pinki Saini   +3 more
wiley   +1 more source