Results 191 to 200 of about 108,777 (376)

Inhibition of digestive proteinase of stored grain coleoptera by oryzacystatin, a cysteine proteinase inhibitor from rice seed [PDF]

, 1991
Chao Liang, Gary L. Brookhart, Guo Hua Feng, Gerald R. Reeck, Karl J. Kramer   +4 more
openalex   +1 more source

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

Advanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He, Haoyu Wang, Zizhen Yang, Hui Li, Bei Liu, Kaiwei Chen, Zhinan Wu, Xinnan Zhao, Hewei Liang, Mengmeng Wang, Xiaofang Li, Yiyi Zhong, Haifeng Zhang, Liang Xiao, Karsten Kristiansen, Jixing Peng, Yuanqiang Zou, Shangyong Li   +17 more
wiley   +1 more source

Discovery of benzyl carbamate inhibitors of coronavirus M^pro enzymes from a legacy collection of cysteine protease inhibitors. [PDF]

J Enzyme Inhib Med Chem
Sá Magalhães Serafim M, Kronenberger T, Francisco KR, de Sousa Reis EV, Gonçalves de Oliveira E, Marcelino E Oliveira FK, Serraglio Fortes I, Maciel Fernandes TH, Barbosa da Silva E, Fajtova P, Skinner DE, Syed RO, Lage de Siqueira-Neto J, Poso A, Fernandes Mota BE, Alves Coelho-Dos-Reis JG, Santos Abrahão J, Gonçalves Maltarollo V, O'Donoghue AJ, Caffrey CR.   +19 more
europepmc   +1 more source

Elastase and its Inhibitors in Intensive Care Medicine [PDF]

, 1990
Fritz, Hans, Jochum, Marianne
core   +1 more source

Correlation between Plasma .ALPHA.-Cysteine Proteinase Inhibitor Level and Pyruvate Kinase Activity in Vitamin E-Deficient Rats.

, 1992
Naoko Harada, Shinichi Saito, Kayoko Minakata   +2 more
openalex   +2 more sources

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

Advanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang, Yihang Xiao, Yingxiao Gao, Mingxuan Wu   +3 more
wiley   +1 more source

Cysteine proteinase inhibitors decrease rankl and lps induced differentiation of human and mouse osteoclast progenitor cells [PDF]

, 2012
Fredrik Strålberg, Petra Henning, I Gjertson, Bert Kindlund, PPC Souza, Emma Persson, Magnus Abrahamson, Franciszek Kasprzykowski, Anders Grubb, Ulf H. Lerner   +9 more
openalex   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Processing of mitochondrial precursor proteins [PDF]

, 1991
Arretz, Michael, Neupert, Walter, Schneider, Helmut, Wienhues, Ulla   +3 more
core  

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

Advanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang   +16 more
wiley   +1 more source