Results 191 to 200 of about 28,630 (299)

Pex6 and ubiquitination regulate topological remodeling of the peroxisomal membrane protein Pex14. [PDF]

J Biol Chem
Yasumitsu T, Yagita Y, Fujiki Y, Tamura S.   +3 more
europepmc   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source

[Cysteine proteinases and their endogenous inhibitors].

Postepy biochemii, 1989
G, Korzus, B, Turyna
openaire   +1 more source

Cruzain Inhibitors for Chagas Disease: Anticorrelated Optimisation Landscapes and the Multiparametric Path to Clinical Candidates. [PDF]

Chem Biol Drug Des
Dos Reis CRC, de Souza HVCM, Parra LC, de Souza GVCM, Zorzanelli BC, Boechat N, Hoelz LVB, Fernandes TVA.   +7 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Chikungunya virus nsP2: Insights into viral replication, pathogenesis, and therapeutic targeting. [PDF]

Virulence
Xu S, Li K, Tan Q, Yuan L, Huang R, Feng Y, Xu K, Zhu Z, Deng L, Deng Y, Ren Y, Yang J, Yang X.   +12 more
europepmc   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Comparative Transcriptome Analysis Reveals Expression of Defense Pathways and Specific Protease Inhibitor Genes in Solanum lycopersicum in Response to Feeding by Tuta absoluta. [PDF]

Insects
Zhou Y, Pan Y, Liu J, Yang W, Shen G.
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Discovery of benzyl carbamate inhibitors of coronavirus M^pro enzymes from a legacy collection of cysteine protease inhibitors. [PDF]

J Enzyme Inhib Med Chem
Sá Magalhães Serafim M, Kronenberger T, Francisco KR, de Sousa Reis EV, Gonçalves de Oliveira E, Marcelino E Oliveira FK, Serraglio Fortes I, Maciel Fernandes TH, Barbosa da Silva E, Fajtova P, Skinner DE, Syed RO, Lage de Siqueira-Neto J, Poso A, Fernandes Mota BE, Alves Coelho-Dos-Reis JG, Santos Abrahão J, Gonçalves Maltarollo V, O'Donoghue AJ, Caffrey CR.   +19 more
europepmc   +1 more source