Results 231 to 240 of about 47,940 (359)

Exposure to specific fungal lectins during adhesion impairs biofilm formation of Listeria on polystyrene. [PDF]

Microb Biotechnol
Janež N, Ladányi M, Sterniša M, Jug B, Zupan T, Peternel T, Sebastijanović A, Perišić Nanut M, Karničar K, Taler-Verčič A, Turk D, Klančnik A, Štrancar J, Sabotič J.   +13 more
europepmc   +1 more source

Beyond Docking: A Multi‐Tier Computational Pipeline for USP7 Inhibitor Optimization

ChemMedChem, Accepted Article.
Ubiquitin‐specific protease 7 (USP7) is a key deubiquitinating enzyme involved in tumor suppression, DNA repair, and epigenetic regulation. Given its critical role in cancer progression, USP7 has emerged as an attractive therapeutic target. In this study, we employed a multi‐tier computational approach, integrating ligand‐based virtual screening ...
Serdar Durdagi, Ehsan Sayyah, Muhammet Eren Ulug, Serdar Durdağı   +3 more
wiley   +1 more source

Use of RecombinantEntamoeba histolyticaCysteine Proteinase 1 To Identify a Potent Inhibitor of Amebic Invasion in a Human Colonic Model

, 2007
Samuel G. Meléndez-López, Scott Herdman, Ken Hirata, Min-Ho Choi, Youngchool Choe, Charles S. Craik, Conor R. Caffrey, Elisabeth Hansell, Bibiana Chávez‐Munguía, Yen‐Ting Chen, William Roush, James H. McKerrow, Lars Eckmann, Jianhua Guo, Samuel L. Stanley, Sharon L. Reed   +15 more
openalex   +1 more source

Glycosylation analysis of two cysteine proteinase inhibitors from Atlantic salmon skin: di-O-acetylated sialic acids are the major sialic acid species on N-glycans [PDF]

, 2001
Anne Ylönen, Nisse Kalkkinen, Juhani Saarinen, Jarl Bøgwald, Jari Helin   +4 more
openalex   +1 more source

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

ChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone, Maria Rosaria Miranda, Francesca Di Matteo, Valeria Napolitano, Michela Aliberti, Simona Musella, Veronica Di Sarno, Gianluigi Lauro, Giuseppe Bifulco, Giacomo Pepe, Giovanna Aquino, Mario Felice Tecce, Isabel Maria Gomez‐Monterrey, Pietro Campiglia, Carmine Ostacolo, Alessia Bertamino, Vincenzo Vestuto, Tania Ciaglia   +17 more
wiley   +1 more source

Is a cysteine proteinase inhibitor involved in the regulation of petal wilting in senescing carnation (Dianthus caryophyllus L.) flowers? [PDF]

, 2002
H. Sugawara, Kenichi Shibuya, Toshihito Yoshioka, Teruyoshi Hashiba, Shigeru Satoh   +4 more
openalex   +1 more source

The Therapeutic Potential of Kiwi Extract as a Source of Cysteine Protease Inhibitors on DNCB-Induced Atopic Dermatitis in Mice and Human Keratinocyte HaCaT Cells. [PDF]

Int J Mol Sci
Yang HR, Zahan MN, Hwang DH, Prakash RLM, Ravi DA, Hong IH, Kim WH, Kim JH, Kim E, Kang C.   +9 more
europepmc   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source

Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3

, 2009
Michal Potempa, Jan Potempa, Tomasz Kantyka, Ky‐Anh Nguyen, Katarzyna Wawrzonek, Surya P. Manandhar, Katarzyna Popadiak, Kristian Riesbeck, Sigrun Eick, Anna M. Blom   +9 more
openalex   +2 more sources

Sequence conservation in the chagasin family suggests a common trend in cysteine proteinase binding by unrelated protein inhibitors [PDF]

, 2002
Daniel J. Rigden, V. V. Mosolov, Michael Y. Galperin   +2 more
openalex   +1 more source