Results 261 to 270 of about 28,630 (299)

Cysteine proteinase inhibitors in elapid and hydrophiid snake venoms

Toxicon, 2002
The ability of elapid and hydrophiid snake venoms to inhibit cathepsin L was tested. All nine species of elapid and three species of hydrophiid snake venoms tested showed inhibition against cathepsin L. All of these venoms tested also showed inhibition against papain as well as against cathepsin L. Among these venoms, two elapid (Laticauda semifasciata
Hidenobu Takahashi
exaly   +3 more sources

Inhibition of cruzipain, the major cysteine proteinase of the protozoan parasite,Trypanosoma cruzi, by proteinase inhibitors of the cystatin superfamily

FEBS Letters, 1995
Cruzipain, the major cysteine proteinase from Trypanosoma cruzi epimastigotes, purified to a sequentially pure form, exists in multiple forms with pI values between 3.7 and 5.1, and an apparent molecular mass of 41 kDa.
Veronika Stoka, Brigita Lenarcic, Juan JOSÉ Cazzulo   +2 more
exaly   +2 more sources

Bullfrog plasma cysteine proteinase inhibitor (CPI)

Immunopharmacology, 1996
Papain is inhibited by bullfrog plasma. CPI was isolated from bullfrog plasma by two step column chromatography; Cm-papain agarose column chromatography followed by FPLC Mono Q column chromatography with addition of benzamidine. Isolated CPI gave a single band on SDS-PAGE under reducing condition, and the molecular weight of reduced CPI was estimated ...
H, Mashiko, H, Takahashi
openaire   +2 more sources

Cysteine proteinase inhibitors produced by mononuclear phagocytes

Cell and Tissue Research, 1984
Monocytes were separated from human peripheral blood and allowed to attach to culture flasks, after which the content and production of a number of cysteine proteinase inhibitors was assayed. These were: a low molecular weight (MW 12000) acid cysteine proteinase inhibitor (ACPI); a low-molecular weight inhibitor of the same size with neutral pH (NCPI),
V K, Hopsu-Havu, I A, Joronen, M, Järvinen, A, Rinne, M, Aalto   +4 more
openaire   +2 more sources

Discovery of a new inhibitor lead of adenovirus proteinase: steps toward selective, irreversible inhibitors of cysteine proteinases

FEBS Letters, 2001
Using the computer docking program EUDOC, in silico screening of a chemical database for inhibitors of human adenovirus cysteine proteinase (hAVCP) identified 2,4,5,7-tetranitro-9-fluorenone that selectively and irreversibly inhibits hAVCP in a two-step ...
Yuan-Ping Pang, Thomas M Kollmeyer, Emanuele Perola   +2 more
exaly   +2 more sources

Caiman Kininogen-Like Cysteine Proteinase Inhibitor

1992
Kininogens are the major mammalian plasma cysteine proteinase inhibitors; a kininogen-like protein was also found in the snake Bothrops jararaca plasma. This communication describes a kininogen-like protein in plasma of Caiman crocodilus vacare. Caiman crude plasma, unlike snake plasma, contains a detectable cysteine proteinase inhibitor. The inhibitor
M S, Araujo, R, Andreotti, A M, Chudzinski, C A, Sampaio, M U, Sampaio   +4 more
openaire   +2 more sources

Assay of α-Cysteine Proteinase Inhibitor in Serum or Plasma

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1982
A new proteinase inhibitor has recently been found in human serum or plasma which specifically inhibits cysteine proteinases such as ficin, papain, bromelain and cathepsin B. However, serum contains alpha 2-macroglobulin which also inhibits these cysteine proteinases and, consequently, interferes with the assay of the new alpha-cysteine proteinase ...
K, Minakata, M, Asano, T, Sato, N, Harada   +3 more
openaire   +2 more sources

Serum α-cysteine proteinase inhibitor levels in pregnancy

Clinical Biochemistry, 1983
Variation in alpha-cysteine proteinase inhibitor levels in human sera were investigated with special attention to the effect of pregnancy and diseases. The inhibitor level in 111 pregnant women, examined by our previous method, increased as the pregnancy advanced.
K, Minakata, M, Asano, H, Mizutani, Y, Kawashima   +3 more
openaire   +2 more sources

Cysteine proteinase inhibitors from rabbit skeletal muscle

International Journal of Biochemistry, 1988
1. Two cysteine proteinase inhibitors, I-T (Mr = 29,000) and I-S (Mr = 10,700), were isolated from rabbit skeletal muscle by means of succesive extraction with a neutral buffer solution, precipitation at pH 3.7, acetone fractionation and gel permeation on Sephadex G-75. 2.
M, Matsuishi, A, Okitani, Y, Hayakawa, H, Kato   +3 more
openaire   +2 more sources

Characterization and Structure of Pineapple Stem Inhibitor of Cysteine Proteinases

Biological Chemistry Hoppe-Seyler, 1992
The complete amino acid sequence of the inhibitor of cysteine proteinases from pineapple stem acetone powder was determined. The inhibitor consists of 52 amino acids and is composed of two polypeptide chains (41 and 11 amino acids) linked via disulphide bonds. It differs from already known sequences in one to four amino acids.
B, Lenarcic, A, Ritonja, B, Turk, I, Dolenc, V, Turk   +4 more
openaire   +2 more sources