Results 31 to 40 of about 53,318 (217)
The effect of vitamin E on the lipid environment of rat hepatocyte membranes
Regulatory Mechanisms in Biosystems, 2022 Tocopherol is one of the known beneficial natural antioxidants ensuring the optimal level of functioning of mammalian organisms. Numerous in vitro and in vivo experiments have shown that the biological role of vitamin E is to prevent the development of ...
S. B. Silonov +3 more
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Acta Neuropathologica Communications, 2020 Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer’s Disease (AD), where they mediate neuroinflammation and neuronal cell-death.
J. Michael +6 more
doaj +1 more source
Leukotriene mechanisms of allergic enterocolitis pathogenesis in young children
Zaporožskij Medicinskij Žurnal, 2018 Purpose of the study was to determine the parameters of lipid mediators of allergic inflammation (cysteinyl leukotrienes C4, D4, E4) by enzyme immunoassay in serum, saliva, urine of young children with allergic enterocolitis.Materials and methods.
O. H. Shadrin, H. A. Haiduchyk
doaj +1 more source
Clinical and Translational Allergy, 2012 Background Allergen induced early phase airway response and airway plasma exudation are predominantly mediated by inflammatory mast cell mediators including histamine, cysteinyl leukotrienes (cysLTs) and thromboxane A2 (TXA2).
Cui Zhi-Hua +3 more
doaj +1 more source
Cysteinyl-leukotrienes contribute to sputum eosinophil chemotactic activity in asthmatics [PDF]
, 2005 peer reviewedBackground: Cysteinyl-leukotrienes are lipid derived mediators involved in asthma. They are able to stimulate eosinophil chemotaxis in vitro. Induced sputum from asthmatics has been shown to contain eosinophil chemotactic activity.
Henket, Monique +9 more
core +1 more source
Cysteinyl leukotriene metabolism of human eosinophils in allergic disease
Allergology International, 2020 Eosinophils are multifaceted immune cells with diverse functions that enhance allergic inflammation. Cysteinyl leukotrienes (cys-LTs), mainly synthesized in eosinophils, are a class of inflammatory lipid mediators produced via multiple enzymatic ...
Jun Miyata +4 more
doaj +1 more source
Cysteinyl leukotriene receptor 1 is dispensable for osteoclast differentiation and bone resorption.
PLoS ONE, 2022 Cysteinyl leukotriene receptor 1 (CysLTR1) is a G protein-coupled receptor for the inflammatory lipid mediators cysteinyl leukotrienes, which are involved in smooth muscle constriction, vascular permeability, and macrophage chemokine release. The Cysltr1
Hirofumi Fujita +8 more
doaj +1 more source
Mechanisms of aspirin-sensitive asthma
Allergology International, 2004 It is now widely accepted that aspirin, along with other non-steroidal anti-inflammatory drugs (NSAIDs), may precipitate asthma attacks in a minority of susceptible individuals.
Sun Ying +2 more
doaj +1 more source
Role of the route of leukotrienes in an experimental model of oral mucositis induced by 5-fluorouracil [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To investigate the participation of cysteinyl leukotrienes in the pathophysiology of oral mucositis. Methods: Oral mucositis was induced in hamsters using 5-fluorouracil (5-FU; 60 and 40 mg/kg; i.p., on days 1 and 2, respectively, and with ...
Viviane Carvalho da Silva +7 more
doaj +2 more sources