International Journal of General Medicine, 2013 Ibrahim M El-Akkary,1 Zeinat Abdel-Fatah El-Khouly,2 Mervat El-Sayed El-Seweify,1 Gihan A El-Batouti,3 Ekhlas Abdel Aziz,2 Abdelnasser I Adam1 1Department of Human Physiology, 2Department of Applied Medical Chemistry, Medical Research Institute ...
El-Akkary IM +5 more
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Cysteinyl-Leukotriene Receptors and Cellular Signals [PDF]
The Scientific World Journal, 2007 Cysteinyl-leukotrienes (cysteinyl-LTs) exert a range of proinflammatory effects, such as constriction of airways and vascular smooth muscle, increase of endothelial cell permeability leading to plasma exudation and edema, and enhanced mucus secretion ...
G. Enrico Rovati, Valérie Capra
doaj +4 more sources
Changes in cysteinyl leukotrienes during and after cardiac surgery with cardiopulmonary bypass in patients with and without chronic obstructive pulmonary disease [PDF]
Journal of Thoracic and Cardiovascular Surgery, 2011 Objective Pulmonary function frequently deteriorates after cardiopulmonary bypass (CPB). Chronic obstructive pulmonary disease (COPD) increases risk of respiratory complications after CPB.
N. de Prost +4 more
semanticscholar +2 more sources
Cysteinyl Leukotriene Pathway and Cancer [PDF]
International Journal of Molecular Sciences, 2021 Cancer remains a leading cause of death worldwide, despite many advances being made in recent decades. Changes in the tumor microenvironment, including dysregulated immunity, may contribute to carcinogenesis and cancer progression. The cysteinyl leukotriene (CysLT) pathway is involved in several signal pathways, having various functions in different ...
Ming-Ju Tsai +7 more
openaire +2 more sources
A critical role for Macrophage-derived Cysteinyl-Leukotrienes in HIV-1 induced neuronal injury. [PDF]
Brain Behav ImmunMacrophages (MΦ) infected with human immunodeficiency virus (HIV)-1 or activated by its envelope protein gp120 exert neurotoxicity. We found previously that signaling via p38 mitogen-activated protein kinase (p38 MAPK) is essential to the neurotoxicity ...
Yuan NY +11 more
europepmc +2 more sources
FIRST 5-DAYS FOLLOW-UP AND CORRELATION STUDY BETWEEN URINARY CYSTEINYL LEUKO TRIENES AND EDEMA VALUES IN PRIMARY SPONTANEOUS SUPRATENTORIAL INTRACEREBRAL HEMO RRHAGE [PDF]
Sanamed, 2014 Background: After intracerebral hemorrhage cysteinyl leukotrienes (C4, D4, E4) are synthetisized in the contact brain parenchyma-extravasated blood and participate in producing of edema formation.
Dolnenec-Baneva Natalia +3 more
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Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes. [PDF]
J Allergy Clin Immunol, 2020 Cysteinyl leukotrienes (CysLTs) are potent prophlogistic mediators in asthmatic patients; however, inhibition of CysLT receptor 1 is not a consistently effective treatment, suggesting additional regulatory mechanisms. Other cysteinyl-containing lipid mediators (LMs) derived from docosahexaenoic acid, namely maresin conjugates in tissue regeneration ...
Levy BD +7 more
europepmc +4 more sources
Transient receptor potential vanilloid 4 activation constricts the human bronchus via the release of cysteinyl leukotrienes. [PDF]
J Pharmacol Exp Ther, 2014 McAlexander MA +3 more
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