Results 91 to 100 of about 49,829 (291)
EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren +15 more
wiley +1 more source
Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis [PDF]
Xinlei Yu, Yun Chau Long
openalex +1 more source
The graphical abstract summarizes the experimental workflow: (1) Preparation of selenium‐containing tea‐derived peptides (TSE‐PP) guided by ADH activation; (2) Purification and LC‐MS/MS identification of selenium‐modified peptides; (3) Molecular docking to reveal peptide‐ADH interactions; (4) Evaluation of hangover‐alleviating and hepatoprotective ...
Lixia Zan +7 more
wiley +1 more source
Multicenter Evaluation on the Efficacy of N-Acetyl Cystine in Relieving the Symptoms of Laryngopharyngeal Reflux Disease [PDF]
So Yean Kim +13 more
openalex +1 more source
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Molecular imprinting for neurology: Materials, applications, and limitations
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma +3 more
wiley +1 more source
We profiled nutritional and physiological markers in captive sifakas, endangered primates from Madagascar, managed in expansive, non‐native forest enclosures. Variation in many markers reflects freely foraged diets and the energy required to maintain homeostasis under more naturalistic conditions.
Lydia K. Greene +5 more
wiley +1 more source
TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury
Amber W. Wang +6 more
openalex +2 more sources
Intracellular Cystine Loading Causes Proximal Tubule Respiratory Dysfunction: Effect of Glycine [PDF]
Abdullah Şakarcan +2 more
openalex +1 more source

