Results 111 to 120 of about 95,243 (337)

Hydrogels Formed by the Self‐Assembly of Collagen‐Mimetic Peptides With a Constrained Backbone Structure

open access: yesChemistry – A European Journal, EarlyView.
Kinked collagen‐mimetic peptides (kinkCMPs), whose backbone is constrained by a disulfide bond, are designed to induce hydrogel formation. The kinked backbone promotes supramolecular assembly into tunable hydrogels with thermal stability depending on length.
Moeka Noto   +4 more
wiley   +1 more source

Free amino acids in a cave beetle \u3cem\u3eDarlingtonea kentuckensis\u3c/em\u3e Valentine (Coleoptera: Carabidae) [PDF]

open access: yes, 1974
Free amino acids of Darlingtonea kentuckensis were investigated by two-dimensional, thin-layer chromatography on Silica Gel G. Thirteen amino acids which could be identifìed (alanine, glutamic acid, glycine, histidine, isoleucine and/or leucine, lysine ...
Sperka, R. J.
core   +2 more sources

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Tiny cystine stones in the gallbladder of a patient with cholecystolithiasis complicating acute cholecystitis: a case report

open access: yesEuropean Journal of Medical Research, 2012
Cystine stones, the main component of which is cystine, are very common urinary calculi, but are rare in the gall bladder. In animals, there has been only one report of cystine gallstones in tree shrews, and to our knowledge, this is the first report of ...
Qiao Tie   +6 more
doaj   +1 more source

Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts. [PDF]

open access: yes, 2019
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD+) are critical for maintaining redox homeostasis. Aging as
Brewer, Gregory J   +3 more
core  

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen   +7 more
wiley   +1 more source

Solar-driven carbon dioxide fixation using photosynthetic semiconductor bio-hybrids. [PDF]

open access: yes, 2019
Solar-driven conversion of carbon dioxide to value-added carbon products is an ambitious objective of ongoing research efforts. However, high overpotential, low selectivity and poor CO2 mass transfer plague purely inorganic electrocatalysts.
Cestellos-Blanco, Stefano   +2 more
core   +1 more source

From Light‐Driven to Dark Synthesis: Streamlining Perfluoroalkyl Selenide Ether Formation

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Two orthogonal and user‐friendly protocols enable the efficient construction of (Se/S)RF bonds from simple dichalcogenides and perfluoroalkyl iodides. Visible‐light irradiation at 395 nm promotes seleno‐ and thioether formation, while a dark KOH/MeCN variant delivers selenoethers in minutes. Both approaches operate under mild, metal‐ and photocatalyst‐
Loydel Torres Barroso   +5 more
wiley   +1 more source

EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease

open access: yesExploration, EarlyView.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren   +15 more
wiley   +1 more source

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