Results 121 to 130 of about 27,857 (278)

Exploring Substituted Dihydroxybenzenes as Urease Inhibitors Through Structure‐Activity Relationship Studies in Soil Incubations

open access: yesChemPlusChem, Accepted Article.
Urea fertilization as nitrogen (N) source is essential for increasing crop productivity. However, it results in significant N loss through ammonia volatilization, nitrate leaching, and nitrous oxide emissions, causing environmental harm and economic loss. Urease, an enzyme in soil, rapidly catalyzes urea hydrolysis to ammonia/ammonium.
Joses Grady Nathanael   +2 more
wiley   +1 more source

Role of Molecular Recognition in l-Cystine Crystal Growth Inhibition

open access: yesCrystal Growth & Design, 2017
l-Cystine kidney stones—aggregates of single crystals of the hexagonal form of l-cystine—afflict more than 20 000 individuals in the United States alone. Current therapies are often ineffective and produce adverse side effects.
L. Poloni   +8 more
semanticscholar   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

The Fanconi syndrome of cystinosis: insights into the pathophysiology

open access: yesThe Turkish Journal of Pediatrics, 2002
Cystinosis is a lysosomal storage disease, and is one of the most common causes of the Fanconi syndrome. In vitro studies of the cystine-loaded tubule provided insights into the pathophysiology of the proximal tubular defect.
Abdullah Sakarcan
doaj   +1 more source

Cystine Stone Formers Have Impaired Health-Related Quality of Life Compared with Noncystine Stone Formers: A Case-Referent Study Piloting the Wisconsin Stone Quality of Life Questionnaire Among Patients with Cystine Stones.

open access: yesJournal of endourology, 2017
INTRODUCTION Cystinuria is a rare cause of urolithiasis. Affected patients have an earlier onset and more aggressive disease than patients with other stone etiologies.
N. Streeper   +3 more
semanticscholar   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen   +7 more
wiley   +1 more source

Electrochemical Biosensors for Cancer Biomarker Detection: Basic Concept, Design Strategy and Cutting‐Edge Development

open access: yesElectrochemical Science Advances, EarlyView.
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley   +1 more source

l-Cystine Diamides as l-Cystine Crystallization Inhibitors for Cystinuria.

open access: yesJournal of Medicinal Chemistry, 2016
l-Cystine bismorpholide (1a) and l-cystine bis(N'-methylpiperazide) (1b) were seven and twenty-four times more effective than l-cystine dimethyl ester (CDME) in increasing the metastable supersaturation range of l-cystine, respectively, effectively ...
Longqin Hu   +13 more
semanticscholar   +1 more source

Ammoniation of Dietary Flavonoids Containing a Pyrogallol Group With Amino Acids at 37°C

open access: yesFood Chemistry International, EarlyView.
Scheme of reaction exploration, synthesis, structural identification, and bioactivities of ammoniated flavonoids. ABSTRACT New research shows that flavonoids containing a pyrogallol group in ring B react with amino acids at 37°C, forming ammoniated derivatives and aldehydes.
Haolin Zhang   +7 more
wiley   +1 more source

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