Results 121 to 130 of about 47,323 (291)
British Journal of Pharmacology, EarlyView.Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin +13 more
wiley +1 more source
ON THE MECHANISM OF THE CONVERSION IN VIVO OF METHIONINE TO CYSTINE
, 1944 Vincent du Vigneaud +3 more
openalex +1 more source
Ecosystem services provided by spiders
Biological Reviews, EarlyView.ABSTRACT Spiders, ubiquitous and abundant predators in terrestrial ecosystems, often are the subjects of an unjust negative perception. However, these remarkable creatures stand as unsung heroes within our ecosystems, contributing a multitude of ecosystem services critical to human well‐being.
Pedro Cardoso +13 more
wiley +1 more source
Cancer Science, EarlyView.We have demonstrated that prestimulation of human lung cancer cells with TGF‐β enhances resistance to doxorubicin‐induced growth inhibition, depending on Smad3 and Smad4 through induction of ALDH1A1. Knockdown of ALDH1A1 suppressed TGF‐β‐induced resistance to doxorubicin, and exogenous expression of ALDH1A1 in SMAD3‐KO cells restored the drug ...
Takashi Yokoyama +2 more
wiley +1 more source
Cancer Science, EarlyView.Our study explores the potential of dauricine, a bioactive compound from Menispermum dauricum, to overcome osimertinib resistance in lung cancer. We demonstrate that dauricine, when combined with osimertinib, induces ferroptosis in resistant lung cancer cells by stabilizing SAT1, a key enzyme in oxidative stress regulation.
Biying Men +16 more
wiley +1 more source
THE UTILIZATION OF CYSTEINE AND CYSTINE BY RAT LIVER WITH THE PRODUCTION OF HYDROGEN SULFIDE
, 1942 C.V. Smythe
openalex +1 more source
On the Determination and Preparation of Cystine [PDF]
Bulletin of the Agricultural Chemical Society of Japan, 1929 T. Kobayashi, Y. Okuka
openaire +2 more sources
Cell Proliferation, EarlyView.Transcriptional and translational characteristics during goat oocyte maturation and identification of key factors, including GTPBP4, for prepubertal goat oocyte maturation. ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational ...
Jianpeng Qin +21 more
wiley +1 more source