Results 151 to 160 of about 27,857 (278)

GENDER AND AGE DISTRIBUTION AND CHEMICAL COMPOSITION OF RENAL STONES

open access: yesGomal Journal of Medical Sciences, 2014
Background: Renal stones are commonest urological disease worldwide. The objective of this study was to analyze the chemical composition of renal stones in relation to gender and age in District Dera Ismail Khan and its adjacent areas, Pakistan ...
Ghazi Khan   +3 more
doaj  

Dietary cystine restriction increases the proliferative capacity of the small intestine of mice.

open access: yesPLoS ONE
Currently, over 88 million people are estimated to have adopted a vegan or vegetarian diet. Cysteine is a semi-essential amino acid, which availability is largely dependent on dietary intake of meat, eggs and whole grains.
Judith C W de Jong   +10 more
doaj   +1 more source

THE CYSTINE CONTENT OF HAIR AND OTHER EPIDERMAL TISSUES

open access: hybrid, 1927
Robert H. Wilson, Howard B. Lewis
openalex   +1 more source

Klebsiella pneumoniae contributes to altered cytotoxicity of thiopurines in vitro: Possible implications of biotransformation and bacterial metabolism

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin   +13 more
wiley   +1 more source

Supersulfide metabolome of exhaled breath condensate applied as diagnostic biomarkers for esophageal cancer

open access: yesCancer Science, Volume 116, Issue 4, Page 1023-1033, April 2025.
This study evaluated the potential of sulfur metabolites as biomarkers for esophageal cancer using blood and exhaled breath condensate (EBC) samples. Absolute quantification analysis revealed elevated levels of cysteine hydropersulfide (CysSSH) and homocysteine hydropersulfide (HomoCysSSH) in patients with esophageal cancer, with HomoCysSSH in plasma ...
Seji Asamitsu   +13 more
wiley   +1 more source

Exploring Long Noncoding RNAs as Regulators of Tumor Ferroptosis: Advances and Challenges

open access: yesCancer Science, EarlyView.
Long noncoding RNAs (lncRNAs) play pivotal roles in regulating gene expression and are closely associated with cancer progression, prognosis, and therapeutic resistance. This review highlights recent advancements in understanding how lncRNAs modulate ferroptosis, a regulated form of cell death characterized by iron‐dependent lipid peroxidation ...
Gang Li   +3 more
wiley   +1 more source

TGF‐β Enhances Doxorubicin Resistance and Anchorage‐Independent Growth in Cancer Cells by Inducing ALDH1A1 Expression

open access: yesCancer Science, EarlyView.
We have demonstrated that prestimulation of human lung cancer cells with TGF‐β enhances resistance to doxorubicin‐induced growth inhibition, depending on Smad3 and Smad4 through induction of ALDH1A1. Knockdown of ALDH1A1 suppressed TGF‐β‐induced resistance to doxorubicin, and exogenous expression of ALDH1A1 in SMAD3‐KO cells restored the drug ...
Takashi Yokoyama   +2 more
wiley   +1 more source

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