Results 201 to 210 of about 49,829 (291)
Tailoring PHA copolymer types via amino acid supplementation in dairy byproduct media. [PDF]
Patil T +7 more
europepmc +1 more source
ABSTRACT Background Gamma‐glutamyltransferase (GGT) is a membrane‐bound enzyme involved in glutathione metabolism and oxidative stress regulation. Although it is traditionally viewed as a liver function marker, emerging evidence suggests that its aberrant expression is closely associated with tumorigenesis, progression, and therapeutic resistance ...
Fei Wang +11 more
wiley +1 more source
OTUB1 Modulates Ferroptosis by Regulating SLC7A11 Ubiquitination in Pancreatic β-Cells. [PDF]
Yoo S +6 more
europepmc +1 more source
Although cellular communication network factor 2 (CCN2) is secreted out to the extracellular environment, intracellular CCN2 rather than re‐incorporated CCN2 from the outside may be involved in its translocation into the nuclei, because translocation of CCN2 into the nucleus was not disturbed by soluble heparin.
Xuan Thi Nguyen +3 more
wiley +1 more source
The dual role of SLC7A11 in tumor drug resistance: mechanisms, challenges, and therapeutic potential. [PDF]
Guo Y, Chen X, Hu J, Su Y, Yin F, Liu X.
europepmc +1 more source
The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori +9 more
wiley +1 more source
Disulfidptosis mechanisms and therapeutic implications in cancer metabolic reprogramming and future perspectives. [PDF]
Chen R, You J, Weng S, Zhao T.
europepmc +1 more source
This paper focuses on selenium, selenocysteine, and GPX4, elaborating on their metabolic functions and mechanisms in mediating immune regulation through autophagy in solid tumors. It explores the characteristics of selenium metabolism in tumors and the roles of related enzymes, providing new directions for cancer treatment.
Liang Yang +7 more
wiley +1 more source
Hydrogen sulfide-dependent activation of human sulfide quinone oxidoreductase. [PDF]
Roman JV +6 more
europepmc +1 more source

