Results 201 to 210 of about 112,393 (379)

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

Cell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, Yang Liu, Lifang Li, Xiuju Chen, Yueguo Li   +13 more
wiley   +1 more source

CANINE CYSTINURIA. THE EFFECT OF FEEDING CYSTINE, CYSTEINE, AND METHIONINE AT DIFFERENT DIETARY PROTEIN LEVELS

, 1942
W.C. Hess, M. X. Sullivan
openalex   +1 more source

Digitally enhanced ketogenic diet versus low‐fat diet for cardio‐renal‐metabolic health in a predominantly Hispanic adult population with overweight or obesity: Pilot randomised clinical trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Individuals respond differently to diets for weight loss and cardio–renal–metabolic health. Advances in digital health and metabolomics hold promise for personalised lifestyle interventions. The study evaluated the feasibility and the preliminary efficacy of a digitally enhanced ketogenic diet compared with a low‐fat diet, and explored ...
Yan Du, Jing Wang, Shiyu Li, Christiane Meireles, Afaf Saliba, Alondra Castillo, Martin Goros, Johnathan Gelfond, Byeong Yeob Choi, Lu Qi, Chengdong Li, Kumar Sharma   +11 more
wiley   +1 more source

An Open-Label, Phase III Study to Assess the Efficacy and Safety of Cysteamine Ophthalmic Solution 0.55% in Japanese Cystinosis Patients

Clinical Ophthalmology
Nobuhiro Goi,1 Fumino Iwata,2 Yoko Sugihara,3 Shingo Higa,1 Taiichiro Chikama4 1Medical Affairs, Viatris Pharmaceuticals Japan G.K., Tokyo, Japan; 2Iwata Eye Clinic, 2-15-21 Nishinakanobu, Shinagawa-ku, Tokyo, 142-0054, Japan; 3Global Clinical Operations,
Goi N, Iwata F, Sugihara Y, Higa S, Chikama T   +4 more
doaj  

THE PRODUCTION OF RADIOACTIVE CYSTINE BY DIRECT BOMBARDMENT IN THE PILE

, 1949
Eric G. Ball, A. K. Solomon, Octavia Cooper   +2 more
openalex   +1 more source

Cystin [PDF]

, 2017
openaire   +1 more source

Tumor‐related epilepsy in glioma: A multidisciplinary overview

Epilepsia, EarlyView.
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci, Giada Pauletto, Antonio Silvani, Elena Pasini, Tamara Ius, Matteo Martinoni, Carlo Alberto Castioni, Andrea Salmaggi, Sofia Asioli, Marta Maschio, Giuseppe Minniti, Enrico Franceschi, Flavio Villani, Roberta Rudà, Eleonora Aronica, the Italian Multidisciplinary Group for Tumor Epilepsy, Paolo Vitali, Damiano Balestrini, Elisa D’Angelo, Lorenzo Bello, Marco Rossi, Marta Padovan, Anna Teresa Giallonardo, Carlo di Bonaventura, Francesco Toni, Angela La Neve, Simona Rizzato, Matteo Pugnaghi, Marco Vindigni, Carmelo Sturiale   +29 more
wiley   +1 more source

Some sources of error in the estimation of cysteine and cystine in complex materials when acid hydrolysis is employed [PDF]

, 1933
J. W. H. Lugg
openalex   +1 more source

On the Determination and Preparation of Cystine [PDF]

Bulletin of the Agricultural Chemical Society of Japan, 1929
T. Kobayashi, Y. Okuka
openaire   +2 more sources

Clioquinol as a new therapy in epilepsy: From preclinical evidence to a proof‐of‐concept clinical study

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects >25 million people worldwide and is often associated with neuroinflammation. Increasing evidence links deficiency or malfunctioning of the enzyme phosphoglycerate dehydrogenase (PHGDH), which converts 3‐phosphoglycerate to generate serine and the neurotransmitter glycine, with (drug‐resistant ...
Karin Thevissen, Annelii Ny, Daniëlle Copmans, Jana Tits, Kenichi Kamata, Eva Gielis, Kevin Longin, Jo Sourbron, Peravina Thergarajan, Tracie Huey‐Lin Tan, Idrish Ali, Nigel C. Jones, Terence J. O'Brien, Mastura Monif, Bridgette D. Semple, Christine Germeys, Benedetta Frizzi, Virginia Minniti, Sebastian Perrone, Carole L. Linster, Ilaria Elia, Ludo Van Den Bosch, Bruno P. A. Cammue, Arnout Voet, Lieven Lagae, Peter de Witte   +25 more
wiley   +1 more source