Results 211 to 220 of about 47,323 (291)

THE OXIDATION OF CYSTINE

open access: yesJournal of Biological Chemistry, 1925
openaire   +2 more sources

Molecular Alterations in Ferroptosis and the Effects of Resveratrol: A Systematic Review

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 7, July 2025.
Ferroptosis is a cell death mechanism characterized by iron overload, accumulation of reactive oxygen species, deficits in glutathione metabolism, lipid peroxidation, and mitochondrial impairments. Resveratrol can prevent or reverse these alterations by chelating iron and upregulating antioxidant defenses. ABSTRACT Ferroptosis is an iron‐dependent cell
Ana Beatriz Dos Santos   +4 more
wiley   +1 more source

Ferroptosis as a therapeutic vulnerability in MDM2 inhibition in dedifferentiated liposarcoma. [PDF]

open access: yesOncol Lett
Yen CC   +11 more
europepmc   +1 more source

THE COLORIMETRIC ESTIMATION OF CYSTINE AND GLUTATHIONE

open access: hybrid, 1927
George Hunter, Blythe Alfred Eagles
openalex   +1 more source

Gene Dosage Sensitivity and Human Genetic Diseases

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.
ABSTRACT Here we review the historical background and contemporary insights into genetic dominance, focusing on haploinsufficiency (HI), that is, when the function of only one allele of a gene is not enough to ensure a normal phenotype in a diploid organism.
Reiner A. Veitia   +2 more
wiley   +1 more source

Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar   +10 more
wiley   +1 more source

Oxidative Stress: Signaling Pathways, Biological Functions, and Disease

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu   +4 more
wiley   +1 more source

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