Exchange of cystine and glutamate across plasma membrane of human fibroblasts.
Shiro Bannai
openalex +1 more source
Saturated fatty acids (SFA) primarily caused greater physical obesity, whereas Trans‐fatty (TFA) led to more pronounced metabolic damage. Both SFA and TFA diets induced obesity and anxiety‐like behaviors. 7‐Nitroindole (7‐NI) improved anxiety‐like behaviors in SFA‐fed mice but not in TFA‐fed.
Jin‐Cui Yang +4 more
wiley +1 more source
The Supersulfide-Producing Activity of Rat Cystathionine γ-Lyase Is Irreversibly Inactivated by L-CysNO but Not by L-GSNO. [PDF]
Araki S +8 more
europepmc +1 more source
Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12
Main Points Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz +9 more
wiley +1 more source
Genetic and clinical characteristics of Japanese cystinuria with exon and exon-intron boundary variants. [PDF]
Sakamoto S +23 more
europepmc +1 more source
The Alkaline Decomposition of Cystin
openaire +1 more source
Research progress of neurovascular units involved in ischemic stroke
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
Fusion of a bacterial cysteine desulfurase to redox-sensitive green fluorescent protein produces a highly sensitive cysteine biosensor for monitoring changes in intracellular cysteine. [PDF]
Caubrière D +7 more
europepmc +1 more source
Altered Metabolism in Idiopathic Pulmonary Fibrosis
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease that ultimately terminates in death or lung transplantation. It is characterized by a restrictive pattern with impaired diffusion capacity, and typically presents with repeated acute exacerbations that result in permanent and progressive loss of respiratory function.
Neal I. Callaghan, Locke Davenport Huyer
wiley +1 more source

