An Isogenic Human Myoblast Cell Model for Cystinosis Myopathy Reveals Alteration of Key Myogenic Regulatory Proteins. [PDF]
Medaer L +13 more
europepmc +1 more source
Effect of Cystine Depletion on Growth-Arrested Human Diploid Fibroblasts
Shiro Bannai +2 more
openalex +2 more sources
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo +9 more
wiley +1 more source
CD24-targeted cystine and glucose oxidase cascade catalytic nanosystem triggers disulfidptosis in neuroblastoma. [PDF]
Mi T +7 more
europepmc +1 more source
Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide [PDF]
Hiroki Sato +3 more
openalex +1 more source
Biological age acceleration associates with Alzheimer's disease plasma biomarker levels
Abstract INTRODUCTION Epigenetic clocks associate with neuropathology and Alzheimer's disease (AD) clinical risk, but findings are mixed regarding whether clocks associate with blood‐based biomarkers and in non‐European populations. METHODS We calculated biological age and age acceleration from blood methylation data in 704 older Hispanic adults and ...
Jaclyn M. Eissman +15 more
wiley +1 more source
Metabolism‐Regulating Nanomedicines for Cancer Therapy
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
SLC7A11 as a bridge between ferroptosis and disulfidptosis: a promising target for tumor treatment. [PDF]
Qiu H +7 more
europepmc +1 more source
Thermal Induced Changes in Cuticle and Cortex to Chemically Treated Hair
ABSTRACT The deterioration of the cuticle and cortex hair due to routine cosmetic practices has been identified as a primary factor contributing to undesirable changes in the esthetic qualities of hair. Chemical and physical treatments can cause significant damage to hair fibers.
C. R. R. C. Lima +4 more
wiley +1 more source
Immunometabolic regulation of disulfidptosis in orthopedic diseases: mechanistic heterogeneity and therapeutic targets. [PDF]
Zhao X +6 more
europepmc +1 more source

