Results 171 to 180 of about 100,040 (330)

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Chemoenzymatically Synthesized O‐Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhiyong Zhang, Ruonan Liang, Kevin C. Hooijschuur, Robert P. de Vries, Zeshi Li, Geert‐Jan Boons   +5 more
wiley   +2 more sources

Cytidine Diphosphate-Ribitol Analysis for Diagnostics and Treatment Monitoring of Cytidine Diphosphate-l-Ribitol Pyrophosphorylase A Muscular Dystrophy [PDF]

, 2019
Walinka van Tol, Monique van Scherpenzeel, Mohammad Alsady, Moniek Riemersma, Esther Hermans, Else Kragt, Giorgio Tasca, Erik‐Jan Kamsteeg, Maartje Pennings, Ellen van Beusekom, R. Jeroen Vermeulen, Hans van Bokhoven, Nicol C. Voermans, Michèl A.A.P. Willemsen, Angel Ashikov, Dirk J. Lefeber   +15 more
openalex   +1 more source

Distinct Metabolomic Alterations Are Associated With Physical Function, Weight Loss, and Muscle Mass in Men With Cancer

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Treatments for cancer cachexia, defined as involuntary weight and muscle mass loss leading to significant functional impairment, remain unavailable partly due to insufficient improvement of clinically meaningful outcomes in current trials.
Lindsey J. Anderson, Lu Xia, Haiming Kerr, Marin Cabrera, Fabien Chu, Jaqueline Rose, Peter C. Wu, Atreya Dash, Sina A. Gharib, Jose M. Garcia   +9 more
wiley   +1 more source

Cytidine Acetylation Yields a Noninflammatory Synthetic Messenger RNA

, 2021
Kellie D. Nance, Supuni Thallala Gamage, Md Masud Alam, Acong Yang, Michaella J. Levy, Courtney N. Link, Laurence Florens, Michael P. Washburn, Shuo Gu, Joost J. Oppenheim, Jordan L. Meier   +10 more
openalex   +1 more source

Combining Correlative Cryogenic Fluorescence and Electron Microscopy and Correlative Cryogenic Super‐Resolution Fluorescence and X‐Ray Tomography—Novel Complementary 3D Cryo‐Microscopy Across Scales to Reveal Nanoparticle Internalization Into Cancer Cells

Microscopy Research and Technique, Volume 89, Issue 2, Page 260-272, February 2026.
A newly established 3D correlative cryogenic fluorescence microscopy, focused ion beam scanning electron microscopy, and soft x‐ray tomography workflow allowed for enough contrast and resolution to quantify the intracellular uptake of zirconyl‐containing inorganic–organic hybrid nanoparticles as a novel chemotherapeutic drug delivery system into ...
Pavitra Sokke Rudraiah, Louisa Herbsleb, Michaela Salakova, Henriette Gröger, Anna Maria Steyer, Frauke Alves, Claus Feldmann, Andreas Walter   +7 more
wiley   +1 more source

Deficient cytidine monophospho-N-acetylneuraminic acid: glycoprotein sialyltransferase activity in a clone of KB cells with altered cell fusion ability.

, 1983
S Toyama, A. Hajime Koyama, S Toyama
openalex   +1 more source

Supplementary Figures and Tables 1-3 from Activation-Induced Cytidine Deaminase Accelerates Clonal Evolution in <i>BCR-ABL1</i>–Driven B-Cell Lineage Acute Lymphoblastic Leukemia

, 2023
Tanja A. Grüber, Mi Sook Chang, Richard Sposto, Markus Müschen   +3 more
openalex   +2 more sources

Metabolomic Insights Into the Impact of a Maternal Western‐Style Diet and Leptin Supplementation During Suckling on Adult Rat Offspring

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Plasma metabolites in adult offspring reflecting metabolic programming during critical developmental windows. ABSTRACT Perinatal nutrition influences offspring metabolic phenotype and obesity risk. This study examines how a maternal obesogenic diet and offspring's leptin supplementation during suckling affect the metabolome in offspring adulthood ...
Catalina A. Pomar, Rocío A. Martin‐Chamorro, Petr Zouhar, Pedro Castillo, Tomas Cajka, Jan Kopecky, Andreu Palou, Mariona Palou, Catalina Picó   +8 more
wiley   +1 more source

Sex differences in the clinical presentation of patients with newly diagnosed multiple myeloma

Cancer, Volume 132, Issue 2, 15 January 2026.
Abstract Introduction Standardized incidence rates of multiple myeloma (MM) are higher among males than females, suggesting that male sex is an important risk factor for MM, which may affect disease etiology, pathogenesis, and clinical presentation. Methods The association of sex with the prevalence of clinical features and chromosomal abnormalities ...
Krystle L. Ong, Kevin D. Arnold, Meredith C. Wessel, Gayatri Ravi, Faith E. Davies, Gareth J. Morgan, Elizabeth E. Brown   +6 more
wiley   +1 more source