Results 181 to 190 of about 56,630 (276)

Hepatoprotective Effects of Maillard Reaction Products From Perinereis aibuhitensis: Identification and Metabolomic Insights in a Mouse Model of Alcoholic Liver Disease

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract summarizes the hepatoprotective effects of Maillard reaction products derived from Perinereis aibuhitensis (P‐MRPs) in alcohol‐induced liver injury. Male ICR mice were fed a Lieber‐DeCarli alcohol liquid diet (1%–5%, w/v) for 6 weeks with or without P‐MRPs treatment.
Tonglei Qiao, Yuchun Lu, Teng Teng, Zichen Deng, Feng Liu, Chun‐E Liu   +5 more
wiley   +1 more source

Intratumoral Mycobacterium abscessus promotes cytidine deaminase mutagenesis in non-small cell lung cancer. [PDF]

Signal Transduct Target Ther
Li X, Li MT, Ou KP, Gao PQ, Xiao AH, Yang J, Li JN, Deng WY, Bie MJ, Huang AL, Shi XF, Long QX.   +11 more
europepmc   +1 more source

Somatic Mitochondrial–Nuclear DNA Transfer in Lymphoproliferative Disorders

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Introduction Somatic mitochondrial–nuclear DNA transfer (SMNT) is a process by which mitochondrial DNA (mtDNA), of varying sizes, integrate into the nuclear genome and has been previously reported in solid tumours. Methods EuroClonality‐NGS DNA Capture sequencing data from 755 lymphoid malignancies and 59 lymphoid cell lines were analysed for ...
James Peter Stewart, Nikos Darzentas, Miguel Alcoceba, Maria Eugenia Sarasquete, Anthony V. Moorman, Mark Catherwood, Binaya Regmi, Christiane Pott, Anton W. Langerak, David Gonzalez   +9 more
wiley   +1 more source

Epitranscriptomic control of cancer: the emerging roles of m⁵C and ac⁴C RNA modifications. [PDF]

Cell Death Discov
Zhong X, Mao J, Zhang J.
europepmc   +1 more source

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

MedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu, Jie Yu, Ying Chen, Shengfang Ge, Lin Ye, Yefei Wang, Yixiong Zhou, Renbing Jia   +7 more
wiley   +1 more source

An Enzymatic Platform for Late‐Stage (Radio)isotope Labelling of Oligonucleotides With Methyltransferases

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
State‐of‐the‐art synthesis of radiolabelled oligonucleotides involves multi‐step synthesis with high costs, extended timelines and significant radioactive waste generation. Herein, a dual‐methyltransferase platform enables late‐stage, site‐specific labelling, overcoming these limitations through reduced costs, faster turnaround and minimal radioactive ...
Christopher R. B. Swanson, Ulrich Kauhl, Martin R. Edelmann, Florian P. Seebeck   +3 more
wiley   +2 more sources

A rapid and efficient in planta assay for assessment of RNA editing factor performance

The Plant Journal, Volume 128, Issue 1, October 2026.
Significance Statement Nuclear‐encoded pentatricopeptide repeat (PPR) proteins perform site‐specific cytidine‐to‐uridine RNA editing in plant organellar transcripts. Their RNA‐binding specificity can be engineered, enabling targeted de novo RNA editing.
Elena Lesch, Dennis Brandt, Markus Schwarzländer, Till Ischebeck   +3 more
wiley   +1 more source

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood, Sathishkumar Kurusamy, Mark Berney, C. Mark Smales, Elizabeth M. Topp, Joanna F. McGouran, Steven Ferguson   +6 more
wiley   +2 more sources

Metabolomics-Based Selection of Biostimulant and Biocontrol Microbial Consortia. [PDF]

Metabolites
Volkova P, Wong JM, Wong J.
europepmc   +1 more source

ASXL1 in proinflammatory macrophages attenuates inflammatory activation and macrophage‐mediated renal tubular epithelial cell damage in acute kidney injury

Physiological Reports, Volume 14, Issue 19, October 2026.
ASXL1 in inflammatory macrophages attenuates renal tubular cell damage through coordinated histone modification of H3K27me3 and H3K4me3 in acute kidney injury. Abstract Macrophages are major contributors to inflammatory responses in acute kidney injury (AKI) and rapidly alter their gene expression through epigenetic regulation.
Yoshiyasu Ogura, Takehito Sugasawa, Masaomi Nangaku, Imari Mimura   +3 more
wiley   +1 more source