Results 181 to 190 of about 80,345 (286)

Correction to: ‘Activation-induced cytidine deaminase and active cytidine demethylation’ [PDF]

open access: yesTrends in Biochemical Sciences, 2016
Almudena R. Ramiro, Vasco M. Barreto
openaire   +1 more source

Periocular Pigmentation After Gemcitabine Monotherapy for Bladder Cancer: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A patient with advanced bladder cancer received antitumor therapy consisting of gemcitabine on days 1 and 8 combined with cisplatin and treliprimab on day 1. Severe periorbital hyperpigmentation occurred 30 min after gemcitabine infusion on day 8. Symmetrical diffuse hyperpigmentation of a dark brown hue with indistinct borders appeared around
Li Juan, Chen Weiping
wiley   +1 more source

Combining drugs that bypass p53 to treat TP53-mutated leukemias. [PDF]

open access: yesBlood Adv
Biswas S   +12 more
europepmc   +1 more source

Cytidine and dCMP Deaminases-Current Methods of Activity Analysis. [PDF]

open access: yesInt J Mol Sci
Ligasová A   +4 more
europepmc   +1 more source

A Facile Strategy for 3′‐Terminal Functionalization of DNA and RNA via On‐Column Conjugation with Integration into Tandem Oligonucleotide Synthesis

open access: yesCurrent Protocols, Volume 6, Issue 5, May 2026.
Abstract Amino‐functionalized oligonucleotides are valuable tools in therapeutics, biosensing, and nanotechnology. Although 5′‐terminal modifications are readily accessible, incorporation at the 3′‐terminus remains more challenging and often requires pre‐functionalized solid supports or specialized reagents. To address these limitations, we developed a
Jagandeep S. Saraya, Derek K. O'Flaherty
wiley   +1 more source

Sialylation in Colorectal Cancer Rewires Antitumor Immunity at the Peritoneal Metastatic Site

open access: yesEuropean Journal of Immunology, Volume 56, Issue 5, May 2026.
This study shows that loss of sialylation in CT26 cells reduces peritoneal tumor burden, correlating with a lower peritoneal cancer index score. These tumors exhibited increased immune infiltration with prominent alterations in the myeloid compartment and immune cell correlations unique to desialylated tumors, indicating profound reshaping of antitumor
Irene van der Haar Àvila   +8 more
wiley   +1 more source

Hypoxia Independently Induces AID Expression in CH12 B Cells

open access: yesEuropean Journal of Immunology, Volume 56, Issue 5, May 2026.
Hypoxia activates the HIF complex (HIF‐1α, HIF‐1β, HIF‐2α) to induce AID expression in B cells independently of cytokine signaling. However, hypoxia alone is insufficient to trigger class switch recombination (CSR), which additionally requires cytokine‐driven chromatin accessibility, highlighting a mechanistic uncoupling between AID induction and ...
Vincent Heyer   +5 more
wiley   +1 more source

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