Results 171 to 180 of about 56,630 (276)

Uridine cytidine kinases govern molnupiravir bioactivation and anti-SARS-CoV-2 activity. [PDF]

open access: yesPLoS Pathog
Shu H   +14 more
europepmc   +1 more source

MIND diet–related plasma proteins are associated with Alzheimer's disease risk

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Adherence to the Mediterranean–Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet is associated with reduced dementia risk, but underlying mechanisms remain unclear. METHODS Plasma proteomics (SomaScan 7k) from 206 Indiana Alzheimer's Disease Research Center participants were analyzed ...
Shane Fernandez   +14 more
wiley   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

open access: yesAnnals of Neurology, Volume 100, Issue 4, Page 808-823, October 2026.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello   +20 more
wiley   +1 more source

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3397-3406, October 2026.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa   +21 more
wiley   +1 more source

The regulatory mechanism and clinical significance of RNA editing in prostate cancer. [PDF]

open access: yesCurr Urol
Li S   +10 more
europepmc   +1 more source

Polyelectrolyte Design Principles for Electrophoretic Drug Delivery. [PDF]

open access: yesAdv Sci (Weinh)
Saarela Unemo H   +8 more
europepmc   +1 more source

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