Results 151 to 160 of about 56,630 (276)

Accelerated Adaptive Evolution of Gram-Negative Bacteria With a Broad-Host-Range Dual Base Editor. [PDF]

Microb Biotechnol
Aparicio T, Capriglia G, Mapelli F, Borin S, de Lorenzo V.   +4 more
europepmc   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, Volume 159, Issue 11, Page 2633-2652, 1 December 2026.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Author Correction: Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins. [PDF]

Nat Commun
Han W, Yuan B, Fan X, Li W, Yuan Y, Zhang Y, Wang S, Shan S, Hafner M, Wang Z, Qiu Z.   +10 more
europepmc   +1 more source

Assessment of Lectin Staining Biomarkers for GNE Myopathy Gene Therapy

Muscle &Nerve, Volume 74, Issue 5, Page 1456-1470, November 2026.
ABSTRACT Introduction/Aims GNE myopathy (GNEM) is a rare, autosomal recessive disorder caused by mutations in the UDP‐N‐acetylglucosamine (GlcNAc) 2‐epimerase/N‐acetylmannosamine (ManNAc) kinase (GNE) gene, which encodes a required enzyme for sialic acid (SA) biosynthesis.
Kristina M. Sattler, Brian J. Paleo, Mackenzie N. Roth, Kara E. Bradley, Megan N. Winkler, Wakako Yoshioka, Ichizo Nishino, Christoph Lepper, Kelly E. Crowe   +8 more
wiley   +1 more source

Cytidine Aminohydrolase

, 2015
The object of this work was to gain some information about the mechanics of action of cytidine aminohydralase from sheep ...
openaire   +1 more source

The Myeloma Risk Variant of TNFRSF13B Shows Reduced NF‐κB Signalling Activity in HEK293 Cells

European Journal of Haematology, Volume 117, Issue 5, Page 1391-1396, November 2026.
ABSTRACT A single nucleotide variant rs34562254 in TNFRSF13B, which encodes TACI (transmembrane activator and CAML interactor), is associated with an increased risk of myeloma and MGUS. This variant encodes a proline to leucine substitution at residue 251 in the long isoform (P251L) and residue 205 in the short isoform (P205L) of TACI.
Richard Muyan Chen, Jackie L. Ludgate, Robert J. Weeks, Heather E. Cunliffe, Ali G. Dohan, Ian M. Morison   +5 more
wiley   +1 more source

Kinetic mechanism of cytidine aminohydrolase [PDF]

Biochemical Journal, 1970
J D, Findlater, M, Smyth, N V, McFerran, B A, Orsi   +3 more
openaire   +2 more sources

On the Calculations of Electron Impact Ionization Cross-Sections for Selected Nucleosides and Deoxyribose Molecules. [PDF]

Molecules
Możejko P.
europepmc   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

Selective oxidation and quantification of m5C in ribonucleosides and RNA in an epigenetic context. [PDF]

RSC Chem Biol
Holschbach K, Walter T, Guglielminotti D, Menke A, Schmidl D, Reuter D, Kögel K, Stroh L, Schneider S, Giehr P, Carell T, Daumann L.   +11 more
europepmc   +1 more source