Results 131 to 140 of about 47,328 (256)

Roles of Metabolomics in Allergic Rhinitis: From Cell to Bedside Investigations. [PDF]

Int J Mol Sci
Saligupta P, Lao-Araya M, Chattipakorn SC, Chattipakorn N, Thonusin C.   +4 more
europepmc   +1 more source

High‐density mutation tracks are associated with proton‐beam irradiation patterns in Sorghum bicolor

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Induced mutagenesis is a cornerstone of crop functional genomics, yet the extent to which distinct radiation sources reshape the spatial distribution of mutations remains difficult to evaluate in reduced‐representation datasets. Here, we analyze a published genotyping‐by‐sequencing (GBS) panel (192,040 loci) to compare proton‐beam and gamma ...
Ezekiel Ahn, Insuck Baek, Seunghyun Lim, Louis K. Prom, Moon S. Kim, Lyndel W. Meinhardt, Clint Magill   +6 more
wiley   +1 more source

Cytidine Deaminase [PDF]

, 2020
openaire   +1 more source

Targeting Human Immunodeficiency Virus Integrase Beyond the Active Site: The Discovery and Development of Allosteric Integrase Inhibitors

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti, Elisa Patacchini, Emanuele Cara, Laura Zarbo, Antonella Messore, Aurora Albano, Giuseppe Ruggieri, Valentina Noemi Madia, Luigi Scipione, Roberta Costi, Roberto Di Santo   +10 more
wiley   +1 more source

Adverse Prognostic Significance of Activation-Induced Cytidine Deaminase in Diffuse Large B-Cell Lymphoma Patients Treated With R-CHOP. [PDF]

Cancer Rep (Hoboken)
Hardianti MS, Anggorowati N, Setiawan SA, Bagaskoro MR, Kurnianda J, Taroeno-Hariadi KW, Purwanto I, Hutajulu SH.   +7 more
europepmc   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, Volume 32, Issue 31, 18 August 2026.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

Increasing TET Expression and 5‐Hydroxymethylcytosine Formation by a Carbocyclic 5‐Aza‐2′‐deoxy‐cytidine Antimetabolite

Angewandte Chemie, Volume 138, Issue 32, 3 August 2026.
The carbocyclic Decitabine analog (cAzadC) incorporates as an antimetabolite weakly into the genome of growing tumor cells, where it triggers a genome‐wide demethylation and a surprisingly strong hydroxymethylation of cytosine, which translates into an efficient in vivo antitumor (AML) effect.
Maike Däther, Elsa Peev, Annika Fröhlich, Binje Vick, Sogol Fatourechi, Gilles Gasparoni, Matthias Heiss, Corinna C. Pleintinger, Emmanuel Asu Bisong, Hans Hurmiz, Davide Guglielminotti, Yasmin V. Gärtner, Tina Aumer, Karsten Spiekermann, Jörn Walter, Irmela Jeremias, Franziska R. Traube, Thomas Carell   +17 more
wiley   +2 more sources

Intratumoral <i>Enterobacter hormaechei</i> drives gemcitabine resistance in pancreatic cancer via <i>cdd</i> _L-mediated drug inactivation. [PDF]

Imeta
Peng JF, Li M, Niu T, Li J, Niu W, Zheng M, Ji Q, Li C, Shao C, Ding K.   +9 more
europepmc   +1 more source

Metabolic Labeling of Phosphatidylethanolamine Lipids in Cells Using Clickable Ethanolamine Analogs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
This work describes the metabolic labeling of phosphatidylethanolamine (PE) lipids using clickable ethanolamine substrate analogs. Post‐derivatization of tagged PE in cells via click chemistry enabled detection using fluorescence microscopy, mass spectrometry, and TLC imaging.
Robert J. Maraski, Jinchao Lou, Todd B. Reynolds, Michael D. Best   +3 more
wiley   +1 more source

Targeting nucleotide metabolism and epigenetic regulation to overcome the differentiation blockade in AML. [PDF]

Leuk Res Rep
Takahashi S.
europepmc   +1 more source