Results 111 to 120 of about 47,328 (256)

Uridine cytidine kinases govern molnupiravir bioactivation and anti-SARS-CoV-2 activity. [PDF]

PLoS Pathog
Shu H, Ludäscher JM, Sharma S, Alam S, Frank L, Hutchinson ES, Tampere M, Lévêque C, van Kuilenburg ABP, Valerie NCK, Altun M, Chabes A, Stenmark P, Rudd SG, Zhang SM.   +14 more
europepmc   +1 more source

Virocell Necromass Provides Limited Plant Nitrogen and Elicits Rhizosphere Metabolites That Affect Phage Dynamics

Plant, Cell &Environment, EarlyView.
ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak, Michelle C. M. van Winden, Thomas V. Harwood, Rachel Neurath, Suzanne M. Kosina, Katherine B. Louie, Matthew B. Sullivan, Simon Roux, Karsten Zengler, Vivek K. Mutalik, Trent R. Northen   +10 more
wiley   +1 more source

Corrigendum to "Integrated amplification of NADPH-regenerating modules enhances cytidine biosynthesis in <i>Escherichia coli</i>" [Synth Syst Biotechnol 12 (2026) 320-329]. [PDF]

Synth Syst Biotechnol
Liu L, Zhang X, Zhu T, Ye T, Li Z, Ding W, Liu H, Fang H.   +7 more
europepmc   +1 more source

Cytidine Aminohydrolase

, 2015
The object of this work was to gain some information about the mechanics of action of cytidine aminohydralase from sheep ...
openaire   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, EarlyView.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

The regulatory mechanism and clinical significance of RNA editing in prostate cancer. [PDF]

Curr Urol
Li S, Li A, Huang Y, Wang Y, Fan M, Jiang X, Bing K, Liang J, Wang K, Xu Z, Wang L.   +10 more
europepmc   +1 more source

Resolution and Quantitation of Ribonucleosides and Deoxyribonucleosides in Digested Genomic DNA by UHPLC–MS/MS

Biomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT Deoxyuridine (dUrd) is often misincorporated into genomic DNA in cancer patients receiving antimetabolite chemotherapy. This activates base excision repair and recruits ataxia telangiectasia‐mutated and Rad3‐related (ATR), which coordinates DNA repair with nucleotide metabolism by facilitating ribonucleotide reductase (RNR) activity ...
Joshua J. Deppas, Reyna Jones, Robert A. Parise, Pinakin Pandya, Christopher J. Bakkenist, Jan H. Beumer   +5 more
wiley   +1 more source

Polyelectrolyte Design Principles for Electrophoretic Drug Delivery. [PDF]

Adv Sci (Weinh)
Saarela Unemo H, Bernacka-Wojcik I, Zhu L, Vleugels MEJ, Hörberg ME, Lindholm C, Berggren M, Simon DT, Arbring Sjöström T.   +8 more
europepmc   +1 more source

Myelodysplastic Syndromes: 2026 Update on Diagnosis, Risk‐Stratification and Management

American Journal of Hematology, Volume 101, Issue 9, Page 2393-2411, September 2026.
ABSTRACT Disease Overview The myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid disorders characterized by peripheral blood cytopenias and increased risk of transformation to acute myelogenous leukemia (AML). MDS occurs more frequently in older males and in individuals with prior exposure to cytotoxic therapy.
Guillermo Garcia‐Manero
wiley   +1 more source

Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi, Shengbin Liu, Danni Dai, Shanhui Jiang, Tingchen Tian, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Fang Liu, Xue Tang, Xin Jiang, Xiangrong Song   +11 more
wiley   +1 more source