Results 111 to 120 of about 80,345 (286)
Synthesis of ethanolamine phosphoglycerides by human platelets.
Journal of Lipid Research, 1975 Platelet homogenates contain an ethanolaminephosphotransferase (EC 2.7.8.1) that catalyzes the synthesis of ethanolamine phosphoglycerides from cytidine-5‘-diphosphate ethanolamine and 1-radyl-2-acyl-sn-glycerols.
F L Call, 2nd, M Rubert
doaj +1 more source
Cytidine photohydration in R17 RNA
Journal of Molecular Biology, 1972 A reductive assay for the determination of cytidine photohydrates (6-hydroxy-5,6-dihydrocytidine) in ultraviolet-irradiated RNA has been developed. The assay is based on the transformation of the unstable photohydrate into the stable reduction product N 1 -ribosyl- N 3 -( γ -hydroxypropyl)-urea in the irradiated RNA.
Department of Biochemistry University of Florida Gainesville, Fla 32601, U.S.A. ( host institution ) +3 more
openaire +3 more sources
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases
Frontiers in Microbiology, 2013 Over 40% of the human genome is recognizable as having been derived from ancient retroelements, transported by an intracellular copy-and-paste process involving an RNA intermediate, with an additional few percent classified as DNA transposable elements ...
Atsushi eKoito, Terumasa eIkeda
doaj +1 more source
A Nonlinear Quantitative Model for Measuring Concentration Ratios From Raman Intensities
Journal of Raman Spectroscopy, EarlyView.Estimating concentration from Raman intensity ratios is complicated by cross‐contributions from overlapping peaks, causing measured ratios to deviate from the linear behavior assumed in conventional quantitative models. This nonlinear method fully accounts for cross‐contributions, allowing estimation of concentration over several orders of magnitude ...
Joseph Razzell Hollis
wiley +1 more source
Regulation of cytidine aminohydrolase [PDF]
Biochemical Journal, 1969 N V, McFerran, M, Smyth, B A, Orsi
openaire +2 more sources
Current Status of Kidney Xenotransplantation in Basic Research
Organ Medicine, EarlyView.Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley +1 more source
Organ Medicine, EarlyView.Cancer‐associated fibroblasts (CAFs) are key regulators of the pancreatic tumor microenvironment. Through metabolic reprogramming, CAFs support tumor growth by providing nutrients and remodeling extracellular matrix. CAF heterogeneity, including myCAF, iCAF, and apCAF subsets, contributes to immune modulation and therapeutic resistance.
Ziyi Qin, Jinyang Ma, Rui Ju, Lei Guo
wiley +1 more source
Biological functions and clinical implications of the CMPK2 across multisystemic diseases
Cell & BioscienceCytidine/Uridine monophosphate kinase 2 (CMPK2) is a crucial enzyme responsible for the phosphorylation of nucleotides, specifically converting cytidine monophosphate (CMP) and uridine monophosphate (UMP) into their respective diphosphates, known as ...
Jia Li +6 more
doaj +1 more source