Results 121 to 130 of about 47,328 (256)

Hypoxia Independently Induces AID Expression in CH12 B Cells. [PDF]

open access: yesEur J Immunol
Heyer V   +5 more
europepmc   +1 more source

Kinetic mechanism of cytidine aminohydrolase [PDF]

open access: yesBiochemical Journal, 1970
J D, Findlater   +3 more
openaire   +2 more sources

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu   +6 more
wiley   +1 more source

DUSP12 Regulates NAT10‐Mediated RNA Acetylation to Modulate DNA Repair and Therapeutic Response in Hepatocellular Carcinoma

open access: yesMedComm, Volume 7, Issue 9, September 2026.
In hepatocellular carcinoma (HCC) cells exposed to doxorubicin, DUSP12 depletion maintains NAT10 phosphorylation, reducing its acetyltransferase activity, which leads to reduced ac4C RNA acetylation, DNA damage response, and DNA break repair, with consequent tumor sensitization.
Viktor Kalbermatter Boell   +6 more
wiley   +1 more source

A hybrid RNA-based reporter assay for robust quantification of cytidine deaminase activity. [PDF]

open access: yesNucleic Acids Res
Ligasová A   +5 more
europepmc   +1 more source

Mitochondrial DNA in Tumor Evolution and Heterogeneity: Characteristics, Technological Advances, Applications and Challenges

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
This review highlights mitochondrial DNA (mtDNA) somatic mutations as an emerging and potent endogenous lineage marker, offering distinct advantages over traditional nuclear genomic (nDNA) approaches. Lineage tracing based on mtDNA mutations has matured into an indispensable tool, providing unprecedented insights into tumor biology and holding ...
Zifeng Ruan   +4 more
wiley   +1 more source

Technologies for engineering repetitive DNA

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

Home - About - Disclaimer - Privacy