Results 121 to 130 of about 47,328 (256)
Hypoxia Independently Induces AID Expression in CH12 B Cells. [PDF]
Heyer V +5 more
europepmc +1 more source
Kinetic mechanism of cytidine aminohydrolase [PDF]
J D, Findlater +3 more
openaire +2 more sources
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
In hepatocellular carcinoma (HCC) cells exposed to doxorubicin, DUSP12 depletion maintains NAT10 phosphorylation, reducing its acetyltransferase activity, which leads to reduced ac4C RNA acetylation, DNA damage response, and DNA break repair, with consequent tumor sensitization.
Viktor Kalbermatter Boell +6 more
wiley +1 more source
A hybrid RNA-based reporter assay for robust quantification of cytidine deaminase activity. [PDF]
Ligasová A +5 more
europepmc +1 more source
This review highlights mitochondrial DNA (mtDNA) somatic mutations as an emerging and potent endogenous lineage marker, offering distinct advantages over traditional nuclear genomic (nDNA) approaches. Lineage tracing based on mtDNA mutations has matured into an indispensable tool, providing unprecedented insights into tumor biology and holding ...
Zifeng Ruan +4 more
wiley +1 more source
Substrate selectivity of the human RNA m<sup>5</sup>C methyltransferase NSUN2. [PDF]
Canepa J +3 more
europepmc +1 more source
Pyrophosphorolysis and enzymic synthesis of cytidine diphosphate glycerol and cytidine diphosphate ribitol [PDF]
openaire +2 more sources
Technologies for engineering repetitive DNA
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley +1 more source

