Results 161 to 170 of about 56,630 (276)
Exploring the Evolutionary Landscape with Targeted In Vivo Hypermutations. [PDF]
Vanapilli Nursimulu T, Ali M, Shin JA.
europepmc +1 more source
Targeted Metabolomic Profiling of Emotional and Reflex Tears: A Paired Exploratory Study. [PDF]
Liu J, Gao X, Liang H, Ye J.
europepmc +1 more source
Thermodynamic mapping of autoxidation pathways at the methyl substituent at position 5 in 1,5‐dimethylcytosine reveals a chemically guided radical reaction network connecting the corresponding methyl, hydroxymethyl, formyl, and carboxyl derivatives.
Vasilii Korotenko, Hendrik Zipse
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Alkyltransferase Ribozyme for Site-Specific N<sup>4</sup>-Cytidine Alkylation. [PDF]
Dorinova E, Walunj MB, Höbartner C.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Base Editors for Engineering Industrial Microorganisms: Types, Applications, and Future Perspectives. [PDF]
Li X, Wu S, Tian P.
europepmc +1 more source
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Pyrophosphorolysis and enzymic synthesis of cytidine diphosphate glycerol and cytidine diphosphate ribitol [PDF]
openaire +2 more sources

