Results 161 to 170 of about 47,328 (256)
Uridine-cytidine kinase 2 as a novel potential prognostic and therapeutic biomarker in gastric cancer. [PDF]
Sun W +6 more
europepmc +1 more source
The power of many: when genetics met yeasts and high‐throughput
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Clickable RNA via 4'-<i>C</i>-Ethynyl Cytidine─A Novel Design for Metabolically Stable Guide RNAs in RNA Editing. [PDF]
Bereiter R, Manjunath A, Beal PA.
europepmc +1 more source
ABSTRACT Ten‐Eleven Translocation 2 (TET2) is an Fe(II)‐ and α‐ketoglutarate‐dependent dioxygenase that initiates active DNA demethylation by oxidizing 5‐methylcytosine (5mC). Beyond this enzymatic role, TET2 links DNA methylation dynamics with chromatin regulation, cellular metabolism, immune‐cell identity, and treatment response in a context ...
XiaoJie Liu +5 more
wiley +1 more source
Cytosolic DNA inhibits rDNA transcription by retaining the RNA polymerase I transcription machinery. [PDF]
Xu Y +6 more
europepmc +1 more source
Abstract Limb‐girdle muscle dystrophy Type R9 (LGMDR9), also known as LGMD Type 2I, is a rare genetic disease caused by partial loss of function of fukutin‐related protein (FKRP) enzyme which glycosylates alpha‐dystroglycan, thereby stabilizing myocytes during contraction.
Daniel D. Gretler +4 more
wiley +1 more source
Gene expression in immune cells infected with Orientia tsutsugamushi and the antigenic variability of 56-kDa type-specific antigen. [PDF]
So-In C +5 more
europepmc +1 more source
Abstract Solid‐phase RNA synthesis is challenging because the 2'‐hydroxyl requires a protecting group that is stable during chain assembly yet easily removable without degrading the product. Driven by the demand for long RNA therapeutics, we report a synthesis method using 2'‐O‐acetal levulinic ester (ALE) ribonucleoside 3'‐O‐phosphoramidites.
Zidi Lyu, Adam Katolik, Masad J. Damha
wiley +1 more source
Author Correction: Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice. [PDF]
Soudais C +17 more
europepmc +1 more source

