Results 231 to 240 of about 56,630 (276)
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Journal of Molecular Biology, 1972
Abstract Between 15 and 30 °C, conversion of cytidine to the 2′, 3′- or 5′-phosphate increases the reactivity towards methoxyamine by twofold or less in both addition to the double bond at C-6 and substitution of the amino group at C-4. With dinucleoside monophosphates, addition is slower than with cytidine 2′(3′) phosphate and is usually slower than
A, Steinschneider, B, Leshem
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Abstract Between 15 and 30 °C, conversion of cytidine to the 2′, 3′- or 5′-phosphate increases the reactivity towards methoxyamine by twofold or less in both addition to the double bond at C-6 and substitution of the amino group at C-4. With dinucleoside monophosphates, addition is slower than with cytidine 2′(3′) phosphate and is usually slower than
A, Steinschneider, B, Leshem
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An Overview of Cytidine Deaminases
International Journal of Hematology, 2006Enzymes that deaminate cytidine to uridine play an important role in a variety of pathways from bacteria to man. Ancestral members of this family were able to deaminate cytidine only in a mononucleotide or nucleoside context. Recently, a family of enzymes has been discovered with the ability to deaminate cytidines on RNA or DNA.
Naveenan, Navaratnam, Rizwan, Sarwar
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Nature, 1949
A STUDY of the crystal structure of cytidine is being carried out by X-ray analysis. The crystal specimens were kindly supplied by Dr. D. O. Jordan, University of Nottingham, and were found to be orthorhombic with {110} dominating. An optical investigation shows that the sign is positive, with α∥c, β∥b and γ∥a Cell dimensions are : a = 13·93 A., b = 14·
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A STUDY of the crystal structure of cytidine is being carried out by X-ray analysis. The crystal specimens were kindly supplied by Dr. D. O. Jordan, University of Nottingham, and were found to be orthorhombic with {110} dominating. An optical investigation shows that the sign is positive, with α∥c, β∥b and γ∥a Cell dimensions are : a = 13·93 A., b = 14·
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The transport of cytidine into rat brain in vivo, and its conversion into cytidine metabolites
Neurochemical Research, 1982Double-labeled cytidine, with a 3H/14C isotope ratio of 20.00, has been intraventricularly injected into the brain of young rats, and its fate followed up to 90 min from administration together time-course of labeling. The injected nucleoside enters the brain as an intact molecule and is immediately utilized without prior degradation.
G. Trovarelli +4 more
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Presence of cytidine 5′-tetraphosphate in commercial samples of cytidine 5′-triphosphate
Analytical Biochemistry, 1983A contaminant compound has been isolated from commercial samples of CTP by ion-exchange chromatography on a Dowex-1 column. It has been characterized as cytidine 5'-tetraphosphate from its ultraviolet spectrum, labile and total phosphate content, and periodate consumption.
M J, Costas +3 more
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Bioelectrochemistry and Bioenergetics, 1986
Abstract The effect of pH on the adsorption and association of cytidine, cytidine-5′-monophosphate and cytidine-5′-diphosphate was studied by phase-sensitive a.c. polarography. At pH ≤ 5.2 and at lower concentrations of N(3)-protonated cytidine or cytidine phosphate, a single-step Frumkin isotherm was obtained, whereas at elevated bulk concentration ...
M.M. Kamal +3 more
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Abstract The effect of pH on the adsorption and association of cytidine, cytidine-5′-monophosphate and cytidine-5′-diphosphate was studied by phase-sensitive a.c. polarography. At pH ≤ 5.2 and at lower concentrations of N(3)-protonated cytidine or cytidine phosphate, a single-step Frumkin isotherm was obtained, whereas at elevated bulk concentration ...
M.M. Kamal +3 more
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Some dihydro-cytidines and -isocytidines
J. Chem. Soc., Perkin Trans. 1, 1974Syntheses of 5,6-dihydrocytidine (IV), 5,6-dihydroisocytidine (V), and the 2-thioanalogue (VII) of the former are described. U.v. spectroscopic data for (V) and its 2-N-methyl and 2,2-di-N-methyl derivatives (IX) and (X) in alcoholic solution reveal amino rather than imino tautomeric states. The n.m.r.
V, Skarić +3 more
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Cytidine Deaminase in Human Lymphocytes
Nature New Biology, 1973PERIPHERAL blood lymphocytes in culture undergo cell division in the presence of the mitogenic stimulant phyto-haemagglutinin (PHA)1. Some of the metabolic processes that occur shortly after stimulation include phosphorylation of membrane bound phosphatidyl inositol2, acetylation of histones3, changes in cyclic GMP levels4, a pronounced elevation of ...
C W, Abell, N W, Marchand
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Fluorescent adenosine and cytidine derivatives
Biochemical and Biophysical Research Communications, 1972Summary The reaction of chloroacetaldehyde with adenosine and cytidine produces a fluorescent product in each case. These products are easily distinguishable spectroscopically by their fluorescence emission maxima. Since the reaction is carried out in aqueous media under mild conditions of pH and temperature, it should prove extremely useful in ...
J R, Barrio, J A, Secrist, N J, Leonard
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The interaction of ribonuclease with cytidine nucleotides
Biochemical and Biophysical Research Communications, 1960Abstract We wish to report some spectrophotometric studies on the interaction of bovine pancreatic ribonuclease A (RNAse) and an enzymically inactive derivative of RNAse with cytidine nucleotides and Zn(II) ions.
A P, MATHIAS, B R, RABIN, C A, ROSS
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