Results 241 to 250 of about 80,345 (286)
Some of the next articles are maybe not open access.
Journal of Molecular Biology, 1972
Abstract Between 15 and 30 °C, conversion of cytidine to the 2′, 3′- or 5′-phosphate increases the reactivity towards methoxyamine by twofold or less in both addition to the double bond at C-6 and substitution of the amino group at C-4. With dinucleoside monophosphates, addition is slower than with cytidine 2′(3′) phosphate and is usually slower than
A, Steinschneider, B, Leshem
openaire +2 more sources
Abstract Between 15 and 30 °C, conversion of cytidine to the 2′, 3′- or 5′-phosphate increases the reactivity towards methoxyamine by twofold or less in both addition to the double bond at C-6 and substitution of the amino group at C-4. With dinucleoside monophosphates, addition is slower than with cytidine 2′(3′) phosphate and is usually slower than
A, Steinschneider, B, Leshem
openaire +2 more sources
A ribozyme that lacks cytidine
Nature, 1999The RNA-world hypothesis proposes that, before the advent of DNA and protein, life was based on RNA, with RNA serving as both the repository of genetic information and the chief agent of catalytic function. An argument against an RNA world is that the components of RNA lack the chemical diversity necessary to sustain life.
J, Rogers, G F, Joyce
openaire +2 more sources
An Overview of Cytidine Deaminases
International Journal of Hematology, 2006Enzymes that deaminate cytidine to uridine play an important role in a variety of pathways from bacteria to man. Ancestral members of this family were able to deaminate cytidine only in a mononucleotide or nucleoside context. Recently, a family of enzymes has been discovered with the ability to deaminate cytidines on RNA or DNA.
Naveenan, Navaratnam, Rizwan, Sarwar
openaire +2 more sources
Nature, 1949
A STUDY of the crystal structure of cytidine is being carried out by X-ray analysis. The crystal specimens were kindly supplied by Dr. D. O. Jordan, University of Nottingham, and were found to be orthorhombic with {110} dominating. An optical investigation shows that the sign is positive, with α∥c, β∥b and γ∥a Cell dimensions are : a = 13·93 A., b = 14·
openaire +2 more sources
A STUDY of the crystal structure of cytidine is being carried out by X-ray analysis. The crystal specimens were kindly supplied by Dr. D. O. Jordan, University of Nottingham, and were found to be orthorhombic with {110} dominating. An optical investigation shows that the sign is positive, with α∥c, β∥b and γ∥a Cell dimensions are : a = 13·93 A., b = 14·
openaire +2 more sources
The transport of cytidine into rat brain in vivo, and its conversion into cytidine metabolites
Neurochemical Research, 1982Double-labeled cytidine, with a 3H/14C isotope ratio of 20.00, has been intraventricularly injected into the brain of young rats, and its fate followed up to 90 min from administration together time-course of labeling. The injected nucleoside enters the brain as an intact molecule and is immediately utilized without prior degradation.
G. Trovarelli +4 more
openaire +3 more sources
Presence of cytidine 5′-tetraphosphate in commercial samples of cytidine 5′-triphosphate
Analytical Biochemistry, 1983A contaminant compound has been isolated from commercial samples of CTP by ion-exchange chromatography on a Dowex-1 column. It has been characterized as cytidine 5'-tetraphosphate from its ultraviolet spectrum, labile and total phosphate content, and periodate consumption.
M J, Costas +3 more
openaire +2 more sources
Bioelectrochemistry and Bioenergetics, 1986
Abstract The effect of pH on the adsorption and association of cytidine, cytidine-5′-monophosphate and cytidine-5′-diphosphate was studied by phase-sensitive a.c. polarography. At pH ≤ 5.2 and at lower concentrations of N(3)-protonated cytidine or cytidine phosphate, a single-step Frumkin isotherm was obtained, whereas at elevated bulk concentration ...
M.M. Kamal +3 more
openaire +1 more source
Abstract The effect of pH on the adsorption and association of cytidine, cytidine-5′-monophosphate and cytidine-5′-diphosphate was studied by phase-sensitive a.c. polarography. At pH ≤ 5.2 and at lower concentrations of N(3)-protonated cytidine or cytidine phosphate, a single-step Frumkin isotherm was obtained, whereas at elevated bulk concentration ...
M.M. Kamal +3 more
openaire +1 more source
Fluorescent adenosine and cytidine derivatives
Biochemical and Biophysical Research Communications, 1972Summary The reaction of chloroacetaldehyde with adenosine and cytidine produces a fluorescent product in each case. These products are easily distinguishable spectroscopically by their fluorescence emission maxima. Since the reaction is carried out in aqueous media under mild conditions of pH and temperature, it should prove extremely useful in ...
J R, Barrio, J A, Secrist, N J, Leonard
openaire +2 more sources
Some dihydro-cytidines and -isocytidines
J. Chem. Soc., Perkin Trans. 1, 1974Syntheses of 5,6-dihydrocytidine (IV), 5,6-dihydroisocytidine (V), and the 2-thioanalogue (VII) of the former are described. U.v. spectroscopic data for (V) and its 2-N-methyl and 2,2-di-N-methyl derivatives (IX) and (X) in alcoholic solution reveal amino rather than imino tautomeric states. The n.m.r.
V, Skarić +3 more
openaire +2 more sources
Prebiotic Formation of Cytidine Nucleotides
Nature, 1971IN contrast to the plausible explanations for proteinoid formation1, there seems to be no satisfactory concept for the genesis of polynucleotide templates in the presumed conditions of the primitive Earth. Only parts of the problem, such as the origin of the bases2,3 and carbohydrates4 and the synthesis of short oligonucleotides5,6, have been subjected
C M, Tapiero, J, Nagyvary
openaire +2 more sources