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Synthesis of molecularly imprinted magnetic nanoparticles for selective cytidine adsorption
Separation Science Plus, 2021 Magnetic molecularly imprinted nanoparticles were fabricated for cytidine adsorption. Molecularly imprinted polymers were prepared by complexing N-methacryloyl-l-histidine/Cu(II) and cytidine as a template molecule in a highly cross-linked polymer ...
Handan Yavuz Alagöz +2 more
exaly +2 more sources
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Phosphorylation of uridine and cytidine by uridine–cytidine kinase
Journal of Biotechnology, 2014Uridine 5'-monophosphate (5'-UMP) and cytidine 5'-monophosphate (5'-CMP) were biosynthesized by recombinant uridine-cytidine kinase (UCK) and acetate kinase (ACK). The ack and uck genes from Escherichia coli K12 and the uck1, uck2 and ack genes from Lactobacillus bulgaricus ATCC 11842 were cloned and inserted into the plasmid pET-28a.
Zhi Zou, Qingbao Ding, Yahui Qian
exaly +3 more sources
Cytidine Alleviates Dyslipidemia and Modulates the Gut Microbiota Composition in ob/ob Mice
Nutrients, 2023 Cytidine and uridine are endogenous metabolites in the pyrimidine metabolism pathway, and cytidine is a substrate that can be metabolized into uridine via cytidine deaminase. Uridine has been widely reported to be effective in regulating lipid metabolism.
Feng Qiu, Xinchi Feng, Kaixia Niu
exaly +2 more sources
Biopolymers, 1971
AbstractThe large change in the electronic absorption spectrum of cytidine on going from an aqueous to an aprotic medium is attributed to the existence of a hydrogen bonded solvent‐solute complex in solvents capable of donating a proton. The spectrum of cytidine in a variety of solvents and the spectra of a number of nontautomerising model compounds ...
W C, Johnson, P M, Vipond, J C, Girod
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AbstractThe large change in the electronic absorption spectrum of cytidine on going from an aqueous to an aprotic medium is attributed to the existence of a hydrogen bonded solvent‐solute complex in solvents capable of donating a proton. The spectrum of cytidine in a variety of solvents and the spectra of a number of nontautomerising model compounds ...
W C, Johnson, P M, Vipond, J C, Girod
openaire +2 more sources
Uridine and cytidine in the brain: Their transport and utilization
Brain Research Reviews, 2006 The pyrimidines cytidine (as CTP) and uridine (which is converted to UTP and then CTP) contribute to brain phosphatidylcholine and phosphatidylethanolamine synthesis via the Kennedy pathway.
Mehmet Cansev
exaly +3 more sources
A ribozyme that lacks cytidine
Nature, 1999The RNA-world hypothesis proposes that, before the advent of DNA and protein, life was based on RNA, with RNA serving as both the repository of genetic information and the chief agent of catalytic function. An argument against an RNA world is that the components of RNA lack the chemical diversity necessary to sustain life.
J, Rogers, G F, Joyce
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Solvolyses of Cytosine and Cytidine
Journal of Pharmaceutical Sciences, 1972It has been confirmed by UV spectrophotometry and TLC that cytosine and cytidine deaminate to uracil and uridine, respectively, at all pH values. These products slowly degrade further in strongly alkaline solutions. Cytidine also undergoes a parallel degradation in strongly alkaline solutions to a nonchromophoric compound, which can be assigned to a ...
E R, Garrett, J, Tsau
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Carbohydrate Research, 1984
Abstract A practical, seven-step synthesis of 5-(β- d -ribofuranosyl)cytosine ( 1 , ψ-cytidine) was achieved. ψ-Uridine was converted into the 2′,3′-isopropylidene acetal 2 in 85% yield. Tosylation of 2 to the 5′-sulfonate 3 , followed by deacetonation, afforded 5′- O -tosyl-ψ-uridine ( 6 ) in good yield.
K W, Pankiewicz +3 more
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Abstract A practical, seven-step synthesis of 5-(β- d -ribofuranosyl)cytosine ( 1 , ψ-cytidine) was achieved. ψ-Uridine was converted into the 2′,3′-isopropylidene acetal 2 in 85% yield. Tosylation of 2 to the 5′-sulfonate 3 , followed by deacetonation, afforded 5′- O -tosyl-ψ-uridine ( 6 ) in good yield.
K W, Pankiewicz +3 more
openaire +2 more sources