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Cytidine deaminase in rheumatoid arthritis

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An Overview of Cytidine Deaminases

International Journal of Hematology, 2006
Enzymes that deaminate cytidine to uridine play an important role in a variety of pathways from bacteria to man. Ancestral members of this family were able to deaminate cytidine only in a mononucleotide or nucleoside context. Recently, a family of enzymes has been discovered with the ability to deaminate cytidines on RNA or DNA.
Naveenan, Navaratnam, Rizwan, Sarwar
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Cytidine Deaminase in Human Lymphocytes

Nature New Biology, 1973
PERIPHERAL blood lymphocytes in culture undergo cell division in the presence of the mitogenic stimulant phyto-haemagglutinin (PHA)1. Some of the metabolic processes that occur shortly after stimulation include phosphorylation of membrane bound phosphatidyl inositol2, acetylation of histones3, changes in cyclic GMP levels4, a pronounced elevation of ...
C W, Abell, N W, Marchand
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Intersubunit Interactions in Human Cytidine Deaminase

Nucleosides, Nucleotides and Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
VINCENZETTI, Silvia, COSTANZI S, CRISTALLI, Gloria, MARIANI P, QUADRINI B, CAMMERTONI N, VITA, Alberto   +6 more
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Diazepinone Nucleosides as Inhibitors of Cytidine Deaminase.

Nucleosides and Nucleotides, 1996
Abstract The synthesis of 2′-deoxy and 2′,3′-dideoxy derivatives of 1-s-D-ribofuranosyl-1,3,4,7-tetrahydro-2H-1,3-diazepin-2-one (2) was undertaken in order to find new cytidine deaminase (CDA) inhibitors and potential adjuvants in anticancer chemotherapy.
G. Cristalli, R. Volpini, S. Vittori, CAMAIONI, Emidio, G. Rafaiani, S. Potenza, A. Vita   +6 more
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Cytidine Deaminase from Human Spleen

1989
No abstract ...
VITA, Alberto, Cacciamani, Tiziana, NATALINI, Paolo, RUGGIERI, Silverio, Magni, Giulio   +4 more
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Cytidine deaminase activity in abnormal pregnancy

International Journal of Gynecology & Obstetrics, 1993
AbstractOBJECTIVE: To determine the usefulness of cytidine deaminase (CTD) activity in the prediction of abnormal pregnancy and the prognosis of fetal outcome. METHOD: The CTD activities in 367 pregnant women and 17 placentas and their cord sera were determined.
T, Okamura, K, Kigasawa, T, Takeuchi, C, Ohta   +3 more
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Activation-induced cytidine deaminase and active cytidine demethylation

Trends in Biochemical Sciences, 2015
The regulation of demethylation in vertebrates has begun to be elucidated in the past decade. However, a possible involvement of activation-induced cytidine deaminase (AID) in this process remains uncertain. We survey the data supporting or casting doubt on such a role, and propose that there is no strong evidence for an involvement of AID in genome ...
Almudena R, Ramiro, Vasco M, Barreto
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Studies on Thermal Stability of Human Cytidine Deaminase

Nucleosides, Nucleotides & Nucleic Acids, 2007
The thermal stability of human cytidine deaminase (CDA), an enzyme involved in pyrimidine metabolism was investigated. With this in view, the residues R68 and Y60, supposed to be involved in the intersubunit interactions and in the catalytic site of CDA, were mutated to glutamine and glycine, respectively.
VINCENZETTI, Silvia, PUCCIARELLI, Stefania, MARIANI P., DE SANCTIS, Giampiero, POLZONETTI, Valeria, NATALINI, Paolo, VITA, Alberto   +6 more
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