Results 21 to 30 of about 38,369 (222)
Cytidine Deaminase—A Marker for Pre-Eclampsia? [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1985 Cytidine deaminase (cytidine aminohydrolase, EC 3.5.4.5) was measured in blood collected for routine antenatal monitoring from 590 unselected pregnant women. The enzyme measurements were made without prior knowledge of the clinical condition of the patients.
T J, Baines, A, Clark
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Activation induced cytidine deaminase: An old friend with new faces. [PDF]
Front Immunol, 2022 Activation induced cytidine deaminase (AID) protein is a member of APOBEC family. AID converts cytidine to uracil, which is a key step for somatic hypermutation (SHM) and class switch recombination (CSR). AID also plays critical roles in B cell precursor
Çakan E, Gunaydin G.
europepmc +2 more sources
AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates
Nature Communications, 2018 The AID/APOBEC cytidine deaminase family are nucleic acid editors, important for antigen receptor expression and thought to have evolved along with vertebrate adaptive immunity.
Mei-Chen Liu +5 more
doaj +1 more source
BMC Cancer, 2020 Background Pancreatic adenosquamous carcinoma has a poor prognosis, with limited prospective trial data to guide optimal treatment. The potential impact of drug metabolism on the treatment response of patients with pancreatic adenosquamous carcinoma is ...
Claire M. Connell +8 more
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Restriction of Foamy Viruses by APOBEC Cytidine Deaminases [PDF]
Journal of Virology, 2006 ABSTRACT Foamy viruses (FVs) are nonpathogenic retroviruses infecting many species of mammals, notably primates, cattle, and cats. We have examined whether members of the apolipoprotein B-editing catalytic polypeptide-like subunit (APOBEC) family of antiviral cytidine deaminases restrict replication of simian FV.
Delebecque, Frédéric +9 more
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APOBEC3G & HTLV-1: Inhibition without deamination
Retrovirology, 2005 APOBEC3G is a cellular cytidine deaminase that was recently identified as the Vif-sensitive antiviral host factor responsible for the restriction of vif-defective HIV-1 in primary human cells and certain non-permissive T cell lines.
Strebel Klaus
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Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms.
PLoS Pathogens, 2021 The APOBEC3 (A3) genes encode cytidine deaminase proteins with potent antiviral and anti-retroelement activity. This locus is characterized by duplication, recombination, and deletion events that gave rise to the seven A3s found in primates.
Mollie M McDonnell +5 more
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In vitro Assay for Cytidine Deaminase Activity of APOBEC3 Protein
Bio-Protocol, 2014 Cytidine deaminases are enzymes that catalyze the removal of an amino group from cytidine, forming uridine. APOBEC3 (ApolipoproteinB mRNA editing enzyme, catalytic polypeptide like) proteins are cytidine deaminases that deaminate cytidines in ...
Smita Nair, Smita Nair
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Resistance of Cyclocytidine to Cytidine Deaminase
Chemical and Pharmaceutical Bulletin, 1973 Deamination of cytidine derivatives especially of cyclocytidine by mouse kidney cytidine deaminase was examined. Cyclocytidine was not deaminated at either pH6.5 or pH7.3 by the enzyme. Furthermore, cyclocytidine did not inhibit the deamination of aracytidine and ([I]/[S])0.5 value for cyclocytidine was over 100.
HOSHI, AKIO +3 more
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A Rapid Approach for Identifying Cell Lines Lacking Functional Cytidine Deaminase. [PDF]
Int J Mol SciCDD plays a pivotal role within the pyrimidine salvage pathway. In this study, a novel, rapid method for the identification of cell lines lacking functional cytidine deaminase was developed. This innovative method utilizes immunocytochemical detection of
Ligasová A, Kociánová M, Koberna K.
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