Phylogenetic distribution of CMP-Neu5Ac hydroxylase (CMAH), the enzyme synthetizing the pro-inflammatory human xeno-antigen Neu5Gc [PDF]
The enzyme CMP-N-acetylneuraminic acid hydroxylase (CMAH) is responsible for thesynthesis of N-glycolylneuraminic acid (Neu5Gc), a sialic acid present on the cell surfaceproteins of most deuterostomes.
Peri, Sateesh
core +1 more source
Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells [PDF]
core +1 more source
Using NMR to Identify Structural Features of Lin28-Regulated miRNAs and mRNAs and as a Tool for Comparing Differences in Cellular Metabolism [PDF]
Part 1 of this thesis seeks to identify shared structural features of Lin28-regulated miRNAs and mRNAs. Lin28 is an evolutionarily conserved, RNA binding protein, highly expressed in stem cells and poorly differentiated cancers, that inhibits ...
O'Day, Elizabeth Mary
core
Stage-Specific Disruption Of Cancer Cell Metabolism By Pfas: Connecting “forever Chemicals” To The Growing Public Health Challenge Of Colorectal Cancer [PDF]
Per and polyfluoroalkyl substances (PFAS), termed “forever chemicals” for their persistence in the environment, are under investigation for their carcinogenic effects, but their specific impacts on colorectal cancer (CRC) progression remain largely ...
O\u27halloran, Hannah
core +1 more source
Targeted metabolomics reveals serum biomarkers and metabolic alterations in cholesterol gallstone patients. [PDF]
Jin W +5 more
europepmc +1 more source
Investigating the utilization mechanism and kinetics of sialic acid mimetics in mammalian cell lines. [PDF]
Visser EA +11 more
europepmc +1 more source
Divergent Enzymatic Synthesis of a Comprehensive Type‑1 Glycan Determinant Library. [PDF]
Bai G +6 more
europepmc +1 more source
A novel SLC17A5 variant in infantile sialic acid storage disease with hyporegenerative anemia: Neuroimaging insights and literature review. [PDF]
Cappozzo F +7 more
europepmc +1 more source
Construction and characterization of new vectors for constitutive or inducible expression of heterologous gene pairs and the identification of a previously unrecognized activator sequence in [PDF]
Xianzong Shi +5 more
core +1 more source

