Parasite virulence factors during falciparum malaria: rosetting, cytoadherence, and modulation of cytoadherence by cytokines [PDF]
To determine virulence factors of isolates of Plasmodium falciparum and the potential role of cytokines in cerebral malaria, 46 Malagasy patients presenting with cerebral (n = 10), severe (n = 10), and uncomplicated (n = 26) malaria were enrolled in a study. The capacity of 21 of 46 P.
Pascal Ringwald+8 more
openalex +3 more sources
Insights into the Cytoadherence Phenomenon of Plasmodium vivax: The Putative Role of Phosphatidylserine [PDF]
Plasmodium vivax is the most geographically widespread and the dominant human malaria parasite in most countries outside of sub-Saharan Africa and, although it was classically recognized to cause benign infection, severe cases and deaths caused by P ...
P. Totino, S. Lopes
semanticscholar +5 more sources
Mycoplasma gallisepticum is a causative agent of chronic respiratory disease in chickens, typically causing great economic losses. Cytoadherence is the critical stage for mycoplasma infection, and the associated proteins are important for mycoplasma ...
Jingjing Qi+10 more
doaj +2 more sources
Editorial: Frontiers in malaria research [PDF]
Ritu Gill+5 more
doaj +2 more sources
Cytoadherence phenotype of infected erythrocytes is associated with specific expression in parasites from children with cerebral malaria [PDF]
BackgroundCytoadherence of Plasmodium falciparum- infected erythrocytes (IEs) in deep microvasculature endothelia plays a major role in the pathogenesis of cerebral malaria (CM). This biological process is thought to be mediated by P.
Talleh Almelli+8 more
core +2 more sources
Pathogenesis of cerebral malaria—inflammation and cytoadherence [PDF]
Despite decades of research on cerebral malaria (CM) there is still a paucity of knowledge about what actual causes CM and why certain people develop it. Although sequestration of P. falciparum infected red blood cells has been linked to pathology, it is
J. Storm, A. Craig
semanticscholar +4 more sources
Cytoadherence characteristics to endothelial receptors ICAM-1 and CD36 of Plasmodium falciparum populations from severe and uncomplicated malaria cases [PDF]
The adhesion of infected red blood cells (IRBCs) to the cell lining of microvasculature is thought to play a central role in the pathogenesis of severe malaria.
Cojean S.+3 more
doaj +2 more sources
BACKGROUND Despite treatment with effective antimalarial drugs, the mortality rate is still high in severe cases of the disease, highlighting the need to find adjunct therapies that can inhibit the adhesion of Plasmodium falciparum-infected erythrocytes (
Marcele Fontenelle Bastos+10 more
openalex +3 more sources
A chromosome 9 deletion in Plasmodium falciparum results in loss of cytoadherence [PDF]
Many lines of Plasmodium falciparum undrgo a deletion of the right end of chromosome 9 during in vitro culture accompanied by loss of cytoadherence and gametocytogenesis.
D. J. Kemp+7 more
doaj +5 more sources
Endothelial glycocalyx regulates cytoadherence in Plasmodium falciparum malaria [PDF]
Malaria is associated with significant microcirculation disorders, especially when the infection reaches its severe stage. This can lead to a range of fatal conditions, from cerebral malaria to multiple organ failure, of not fully understood pathogenesis.
Viola Introini+4 more
semanticscholar +5 more sources