Results 31 to 40 of about 6,252 (195)

Plasmodium falciparum secretome in erythrocyte and beyond

Frontiers in Microbiology, 2016
Plasmodium falciparum is the causative agent of deadly malaria disease. It is an intracellular eukaryote and completes its multi-stage life cycle spanning the two hosts viz, mosquito and human.
Rani eSoni, Drista eSharma, Tarun Kumar Bhatt   +2 more
doaj   +1 more source

Plasmodium falciparum:Rosettes do not protect merozoites from invasion-inhibitory antibodies [PDF]

, 2006
Rosetting is a parasite adhesion phenotype associated with severe malaria in African children. Why parasites form rosettes is unknown, although enhanced invasion or immune evasion have been suggested as possible functions.
Angus, Anne-Marie Deans, Artavanis-Tsakonas, Blackman, Carlson, Clough, Cockburn, David, Handunnetti, J. Alexandra Rowe, Kaul, Kawai, Lambros, Lowe, Mackinnon, McBride, Nash, Newbold, Pasvol, Ringwald, Rowe, Rowe, Rowe, Rowe, Singh, Udomsanpetch, Urban, Wahlgren   +27 more
core   +1 more source

Endothelial glycocalyx regulates cytoadherence inPlasmodium falciparummalaria [PDF]

Journal of The Royal Society Interface, 2018
Malaria is associated with significant microcirculation disorders, especially when the infection reaches its severe stage. This can lead to a range of fatal conditions, from cerebral malaria to multiple organ failure, of not fully understood pathogenesis.
Introini, Viola, Carciati, Antonio, Tomaiuolo, Giovanna, Cicuta, Pietro, Guido, Stefano   +4 more
openaire   +4 more sources

Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome

Journal of Immunology Research, 2019
The severity of Plasmodium falciparum malaria is associated with parasite cytoadherence, but there is limited knowledge about the effect of parasite cytoadherence in malaria-associated acute respiratory distress syndrome (ARDS).
Luana dos Santos Ortolan, Michelle Klein Sercundes, Gabriel Candido Moura, Thatyane de Castro Quirino, Daniela Debone, Douglas de Sousa Costa, Oscar Murillo, Claudio Romero Farias Marinho, Sabrina Epiphanio   +8 more
doaj   +1 more source

Clinical and molecular aspects of severe malaria

Anais da Academia Brasileira de Ciências, 2005
The erythrocytic cycle of Plasmodium falciparum presents a particularity in relation to other Plasmodium species that infect man. Mature trophozoites and schizonts are sequestered from the peripheral circulation due to adhesion of infected erythrocytes ...
Karin Kirchgatter, Hernando A. Del Portillo   +1 more
doaj   +1 more source

Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution [PDF]

, 2018
Although Plasmodium vivax is responsible for the majority of malaria infections outside Africa, little is known about its evolution and pathway to humans. Its closest genetic relative, P.
Arnathau, Céline, Boundenga, Larson, Durand, Patrick, Franzon, Blaise, Gilabert, Aude, Makanga, Boris, Moukodoum, Nancy D., Ngoubangoye, Barthélémy, Okouga, Alain-Prince, Ollomo, Benjamin, Otto, Thomas D., Paupy, Christophe, Prugnolle, Franck, Renaud, François, Rougeron, Virginie, Rutledge, Gavin G.   +15 more
core   +4 more sources

Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage [PDF]

Malaria Journal, 2011
The adhesion of Plasmodium falciparum parasitized red blood cell (PRBC) to human endothelial cells (EC) induces inflammatory processes, coagulation cascades, oxidative stress and apoptosis. These pathological processes are suspected to be responsible for the blood-brain-barrier and other organs' endothelial dysfunctions observed in fatal cases of ...
Taoufiq, Zacharie, Pino, Paco, N'Dilimabaka, Nadine, Arrouss, Issam, Assi, Serge, Soubrier, Florent, Rebollo, Angelita, Mazier, Dominique   +7 more
openaire   +3 more sources

PfEMP1 A-Type ICAM-1-Binding Domains Are Not Associated with Cerebral Malaria in Beninese Children

mBio, 2020
PfEMP1 is the major antigen involved in Plasmodium falciparum-infected erythrocyte sequestration in cerebrovascular endothelium. While some PfEMP1 domains have been associated with clinical phenotypes of malaria, formal associations between the ...
V. Joste, E. Guillochon, J. Fraering, B. Vianou, L. Watier, S. Jafari-Guemouri, M. Cot, S. Houzé, A. Aubouy, J. F. Faucher, N. Argy, G. I. Bertin   +11 more
doaj   +1 more source

Virulence of malaria is associated with differential expression of Plasmodium falciparum var gene subgroups in a case-control study [PDF]

, 2006
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a major pathogenicity factor in falciparum malaria that mediates cytoadherence. PfEMP1 is encoded by approximately 60 var genes per haploid genome.
Baea, Kay, Beck, Hans-Peter, Cockburn, Ian A, Cortés, Alfred, Kaestli, Mirjam, Rowe, J Alexandra   +5 more
core   +1 more source

Clinical correlates of in vitro Plasmodium falciparum cytoadherence [PDF]

Infection and Immunity, 1991
To determine whether isolates of Plasmodium falciparum have intrinsically different cytoadherent properties and whether these differences contribute to the clinical severity of human falciparum malaria, we studied the cytoadherence to C32 melanoma cells in vitro of 59 parasite isolates from patients with naturally acquired infections in Thailand ...
Ho, M, Singh, B, Looareesuwan, S, Davis, T, Bunnag, D, White, N   +5 more
openaire   +3 more sources