Results 31 to 40 of about 42,407 (161)

The rate of hypo-osmotic challenge influences regulatory volume decrease (RVD) and mechanical properties of articular chondrocytes [PDF]

, 2015
Zhao Wang is funded on a China Scholarships PhD Studentship. Jerome Irianto was supported on a project grant from The Wellcome Trust (ref no. 084717)
Baaijens, Bader, Borghetti, Bush, Bush, Bush, Bush, Cantiello, Chalut, Chao, Chen, Dahl, Darling, Erickson, Fletcher, Guilak, Guilak, Guilak, Hopewell, Huttu, Irianto, J. Irianto, Jones, Kerrigan, Kerrigan, Kerrigan, Knight, Knight, Koay, Korhonen, Leipzig, Li, Lohr, M.M. Knight, McArthur, Mobasheri, Moran, Ohashi, Okada, Okumura, Ordaz, Pajerowski, Phan, Pravincumar, Pritchard, Quist, Qusous, Qusous, S. Kazun, Sato, Souza, Stewart, Theret, Trickey, Trickey, Turunen, Urban, Urban, Van Inwegen, Voets, W. Wang, Z. Wang   +61 more
core   +1 more source

Cytochalasin A and B

Journal of Biological Chemistry, 1972
Abstract A mold metabolite, cytochalasin B, inhibits uptake of 2-deoxy-d-glucose in chick fibroblasts and cultured liver cells. This inhibition is rapid, reversible, and is achieved at very low concentrations of the metabolite. Cytochalasin A also inhibits sugar uptake, but the magnitude and reversibility of inhibition differs from that produced by ...
Andria Springer, James F. Perdue, Rolf F. Kletzien   +2 more
openaire   +3 more sources

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration? [PDF]

, 2017
Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid laden macrophages (LLM) within the airway may indicate aspiration secondary to GOR.
Adams, Ahrens, Anderson, Greenman, Nakahira, Pacheco-Galván, Porcheray   +6 more
core   +2 more sources

Effects of Cytochalasin B On Mammalian Melanocytes and Keratinocytes

Journal of Investigative Dermatology, 1972
A study was carried out on the in vitro effects cytochalasin B on melanocytes and keratinocytes obtained from guinea pig skin. Observations of cell cultures made with time-lapse cinematography and electron microscopy show that cytochalasin produces marked changes in cell morphology.
George Szabo, Muriel A. Wikswo
openaire   +3 more sources

UTX Responds to Nanotopography to Suppress Macrophage Inflammatory Response by Remodeling H3K27me3 Modification

Advanced Science, EarlyView.
Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia, He Zhang, Dingqiang Mo, Bo Xie, Hongdou Qiao, Tao Chen, Haoyue Song, Xinxin Xu, Sheng Yang   +8 more
wiley   +1 more source

Optical measurement of osmotic water transport in cultured cells. Role of glucose transporters. [PDF]

, 1992
Methodology was developed to measure osmotic water permeability in monolayer cultured cells and applied to examine the proposed role of glucose transporters in the water pathway (1989. Proc. Natl. Acad. Sci. USA. 86:8397-8401).
Echevarria, M, Verkman, AS
core  

Construction of Active Sites‐Accessible Au8 Clusters for Intensive Tumor Pyroptosis

Aggregate, EarlyView.
Ethynylferrocene (EFc) was utilized to engineer molecular‐like gold nanoclusters (NCs) with accessibly catalytic centers, resulting in NCs exhibiting excellent peroxidase‐like activity and the ability to radiosensitize, leading to the production of intracellular oxidative stress and activation of pyroptosis.
Qiu‐Xu Zang, Wei‐Tong Chen, Wenjing Zhang, Zhao‐Yang Wang, Xi‐Yan Dong, Runping Han, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Uptake and transport of novel amphiphilic polyelectrolyte-insulin nanocomplexes by caco-2 cells - towards oral insulin [PDF]

, 2011
“The original publication is available at www.springerlink.com”. Copyright SpringerPurpose: The influence of polymer architecture on cellular uptake and transport across Caco-2 cells of novel amphiphilic polyelectrolyte-insulin nanocomplexes was ...
A Bayat, A Jintapattanakit, A Lin, AF Kotzé, AF Kotzé, AF Kotzé, AF Kotzé, Alastair McKinnon, AMM Sadeghi, CJ Thompson, CJ Thompson, CJ Thompson, CM Lehr, CM Lehr, Colin Thompson, F Qian, G Ranaldi, Gillian Smith, H Gersdorff von, IM Lubben van der, JH Hamman, JJH Chu, JP Bai, Karen Skene, KS Soppimath, L Yin, M Bendayan, M Mahkam, M Simon, M Simon, M Thanou, M-K Kim, Mhairi Smith, MM Thanou, N Nishiyama, NJ Kavimandan, P Artursson, Pramod Gadad, PS Pourhosseini, Rachel Knott, RJ Schilling, S Mao, S Sakuma, T Jung, Woei Ping Cheng, X Boulenc, Y-Y Huang   +46 more
core   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source