Actin cytoskeleton-dependent regulation of corticotropin-releasing factor receptor heteromers [PDF]
, 2017 Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein–coupled receptors, are pivotal in mediating ...
Bhargava, Aditi +7 more
core +1 more source
Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. [PDF]
, 1984 We have determined the effect of various endocytic ligands on the secretion of ApoE by macrophages. ApoE was a major secreted protein of resident macrophages, but BCG-activated macrophages secreted little ApoE and periodate-elicited macrophages secreted ...
Takemura, R, Werb, Z
core +2 more sources
YAP/TAZ regulates the expression of proteoglycan 4 and tenascin C in superficial-zone chondrocytes [PDF]
European Cells & Materials, 2020 The roles of cell division control protein 42 homologue (CDC42) and actin polymerisation in regulating the phenotype of superficial-zone chondrocytes (SZCs) have been demonstrated in vitro; however, the signalling pathway(s) downstream have yet to be ...
E Delve +5 more
doaj +1 more source
Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization,secondary mediators, and Rac [PDF]
, 2010 The C-type lectin-like receptor 2 (CLEC-2)activates platelets through Src and Syk tyrosine kinases via a single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM).Here, we demonstrate using sucrose gradient ...
Alice Y. Pollitt +44 more
core +1 more source
On the dynamics of the microfilament system in HeLa cells [PDF]
, 1982 We measured the pools of unpolymerized and filamentous actin in homogenates of HeLa cells made in several different lysis buffers, as well as after treatment of cells with a variety of chemicals or trypsin, and after adenovirus (type 2) infection.
Blikstad, Ingrid, Carlsson, Lars
core +3 more sources
Quantitative image mean squared displacement (iMSD) analysis of the dynamics of profilin 1 at the membrane of live cells. [PDF]
, 2018 Image mean square displacement analysis (iMSD) is a method allowing the mapping of diffusion dynamics of molecules in living cells. However, it can also be used to obtain quantitative information on the diffusion processes of fluorescently labelled ...
Davey, Rhonda J +3 more
core +1 more source
Analysis of Apoptosis on the Somatic Cell Nuclear Transfer embryos in porcine
Journal of Animal Reproduction and Biotechnology, 2018 The purpose of this study is to examined the electrofusion and activation conditions for the production of porcine somatic cell nuclear transfer (SCNT) embryos.
Ji-Eun Ryu, Jong-Taek Yoon
doaj +1 more source
Molecules, 2021 In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A–D (1–4), were characterized from the fungus Zopfiella sp.
Jie-Yu Zhang +4 more
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
A pharmacological cocktail for arresting actin dynamics in living cells. [PDF]
, 2011 The actin cytoskeleton is regulated by factors that influence polymer assembly, disassembly, and network rearrangement. Drugs that inhibit these events have been used to test the role of actin dynamics in a wide range of cellular processes.
Peng, Grace E +2 more
core +2 more sources