Results 51 to 60 of about 42,571 (229)

Stathmin mediates TNF-α-induced skin fibroblast migration by promoting formation of filopodia

open access: yesDi-san junyi daxue xuebao, 2022
Objective To explore the effect and preliminary mechanism of stathmin on skin fibroblast migration in the early inflammatory reaction of wound healing mimicked by TNF-α stimulation.
CEN Ruiyan   +6 more
doaj   +1 more source

D-mannose transport and metabolism in isolated enterocytes [PDF]

open access: yes, 2004
D-mannose transport and metabolism has been studied in enterocytes isolated from chicken small intestine. In the presence of Na+, the mannose taken up by the cells either remains free, is phosphorylated, is catabolized to H2O, or becomes part of membrane
Cano Rodríguez, María Mercedes   +3 more
core   +1 more source

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu   +7 more
wiley   +1 more source

Investigation of microsphere-mediated cellular delivery by chemical, microscopic and gene expression analysis [PDF]

open access: yes, 2010
Amino functionalised cross-linked polystyrene microspheres of well defined sizes (0.2-2 mm) have been prepared and shown to be efficient and controllable delivery devices, capable of transporting anything from small dye molecules to bulky proteins into ...
Akhtar   +50 more
core   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

open access: yesAdvanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin   +12 more
wiley   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

BLOOD LIPOPROTEINS AS A PLATFORM FOR TRANSPORT OF HYDROPHILIC AND HYDROPHOBIC COMPOUNDS

open access: yesСибирский научный медицинский журнал, 2019
The paper discusses the transport functions of the main classes of blood plasma lipoproteins (LP) that are not associated with the metabolism of lipids that make up their composition.
L. M. Polyakov   +4 more
doaj   +1 more source

Optical measurement of osmotic water transport in cultured cells. Role of glucose transporters. [PDF]

open access: yes, 1992
Methodology was developed to measure osmotic water permeability in monolayer cultured cells and applied to examine the proposed role of glucose transporters in the water pathway (1989. Proc. Natl. Acad. Sci. USA. 86:8397-8401).
Echevarria, M, Verkman, AS
core  

Cell contraction induces long-ranged stress stiffening in the extracellular matrix [PDF]

open access: yes, 2017
Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains largely unknown ...
Broedersz, Chase P.   +7 more
core   +2 more sources

Cytochalasin B: Inhibition of Glucose and Glucosamine Transport [PDF]

open access: yesProceedings of the National Academy of Sciences, 1972
Cytochalasin B has been shown to potently inhibit the transport of glucose, deoxyglucose, and glucosamine by Novikoff hepatoma cells in suspension culture without affecting their intracellular phosphorylation and metabolism. Deoxyglucose transport is inhibited by cytochalasin B in a simple competitive manner.
R D, Ebstensen, P G, Plagemann
openaire   +2 more sources

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