Cytochalasins as Modulators of Stem Cell Differentiation [PDF]
Regenerative medicine aims to identify new research strategies for the repair and restoration of tissues damaged by pathological or accidental events. Mesenchymal stem cells (MSCs) play a key role in regenerative medicine approaches due to their specific
Luca Pampanella +6 more
doaj +5 more sources
Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery [PDF]
Investigating the chemical diversity of natural products from tropical environments is an inspiring approach to developing new drug candidates for neglected tropical diseases (NTDs).
Marilia Valli +6 more
doaj +5 more sources
Isolation, Structural Analyses and Biological Activity Assays against Chronic Lymphocytic Leukemia of Two Novel Cytochalasins — Sclerotionigrin A and B [PDF]
Two new cytochalasins, sclerotionigrin A (1) and B (2) were isolated together with the known proxiphomin (3) from the filamentous fungus Aspergillus sclerotioniger.
Lene M. Petersen +6 more
doaj +5 more sources
Epigenetic Manipulation Induced Production of Immunosuppressive Chromones and Cytochalasins from the Mangrove Endophytic Fungus Phomopsis asparagi DHS-48 [PDF]
A mangrove endophytic fungus Phomopsis asparagi DHS-48 was found to be particularly productive with regard to the accumulation of substantial new compounds in our previous study.
Ting Feng +5 more
doaj +3 more sources
Immunosuppressive Cytochalasins from the Mangrove Endophytic Fungus Phomopsis asparagi DHS-48 [PDF]
Three new cytochalasins, phomoparagins A-C (1–3), along with five known analogs (4–8), were isolated from Phomopsis asparagi DHS-48, a mangrove-derived endophytic fungus.
Zhao Feng +7 more
doaj +3 more sources
Pentacyclic Cytochalasins and Their Derivatives from the Endophytic Fungus Phomopsis sp. xz-18 [PDF]
Eight new cytochalasins 1–8 and ten known analogs 9–18 were isolated from the endophytic fungus Phomopsis sp. xz-18. The planar structures of the cytochalasins were determined by HR-ESI-MS and NMR analysis.
Guichon Huang +7 more
doaj +3 more sources
The Cytochalasins and Polyketides from a Mangrove Endophytic Fungus Xylaria arbuscula QYF [PDF]
Twelve compounds, including four undescribed cytochalasins, xylariachalasins A–D (1–4), four undescribed polyketides (5–8), and four known cytochalasins (9–12), were isolated from the mangrove endophytic fungus Xylaria arbuscula QYF. Their structures and
Qi Tan +10 more
doaj +3 more sources
Zopfiellasins A–D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment [PDF]
In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A–D (1–4), were characterized from the fungus Zopfiella sp.
Jie-Yu Zhang +4 more
doaj +3 more sources
Bioactive Phenylalanine Derivatives and Cytochalasins from the Soft Coral-Derived Fungus, Aspergillus elegans [PDF]
One new phenylalanine derivative 4′-OMe-asperphenamate (1), along with one known phenylalanine derivative (2) and two new cytochalasins, aspochalasin A1 (3) and cytochalasin Z24 (4), as well as eight known cytochalasin analogues (5–12) were isolated from
Xue-Ping Sun +8 more
doaj +3 more sources
Abstract Cytochalasin B (2 to 4 µg/ml) reversibly inhibits the chemotactic response of human and rabbit polymorphonuclear leukocytes to a bacterial chemotactic factor or to the complement derived factor, C5a. At lower concentrations (1 to 0.1 µg/ml or less) Cytochalasin B actually stimulates chemotaxis.
Elmer L Becker +3 more
+4 more sources

