Results 1 to 10 of about 18,833 (262)

Cytochalasins as Modulators of Stem Cell Differentiation. [PDF]

Cells
Regenerative medicine aims to identify new research strategies for the repair and restoration of tissues damaged by pathological or accidental events. Mesenchymal stem cells (MSCs) play a key role in regenerative medicine approaches due to their specific properties, such as the high rate of proliferation, the ability to differentiate into several cell ...
Pampanella L, Petrocelli G, Abruzzo PM, Zucchini C, Canaider S, Ventura C, Facchin F.   +6 more
europepmc   +6 more sources

Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery. [PDF]

PLoS One, 2022
Investigating the chemical diversity of natural products from tropical environments is an inspiring approach to developing new drug candidates for neglected tropical diseases (NTDs).
Valli M, Souza JM, Chelucci RC, Biasetto CR, Araujo AR, Bolzani VDS, Andricopulo AD.   +6 more
europepmc   +4 more sources

Immunosuppressive Cytochalasins from the Mangrove Endophytic Fungus Phomopsis asparagi DHS-48. [PDF]

Mar Drugs, 2022
Three new cytochalasins, phomoparagins A-C (1–3), along with five known analogs (4–8), were isolated from Phomopsis asparagi DHS-48, a mangrove-derived endophytic fungus.
Feng Z, Zhang X, Wu J, Wei C, Feng T, Zhou D, Wen Z, Xu J.   +7 more
europepmc   +3 more sources

Pentacyclic Cytochalasins and Their Derivatives from the Endophytic Fungus Phomopsis sp. xz-18. [PDF]

Molecules, 2021
Eight new cytochalasins 1–8 and ten known analogs 9–18 were isolated from the endophytic fungus Phomopsis sp. xz-18. The planar structures of the cytochalasins were determined by HR-ESI-MS and NMR analysis.
Huang G, Lin W, Li H, Tang Q, Hu Z, Huang H, Deng X, Xu Q.   +7 more
europepmc   +3 more sources

Isolation, Structural Analyses and Biological Activity Assays against Chronic Lymphocytic Leukemia of Two Novel Cytochalasins - Sclerotionigrin A and B [PDF]

Molecules, 2014
Two new cytochalasins, sclerotionigrin A (1) and B (2) were isolated together with the known proxiphomin (3) from the filamentous fungus Aspergillus sclerotioniger.
Bladt, Tanja Thorskov, Duerr, Claudia, Frisvad, Jens Christian, Gotfredsen, Charlotte Held, Larsen, Thomas Ostenfeld, Petersen, Lene Maj, Seiffert, Martina   +6 more
core   +5 more sources

Zopfiellasins A-D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment. [PDF]

Molecules, 2021
In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A–D (1–4), were characterized from the fungus Zopfiella sp.
Zhang JY, He J, Li ZH, Feng T, Liu JK.
europepmc   +3 more sources

Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity. [PDF]

Pharmaceuticals (Basel), 2023
Six previously undescribed cytochalasins, Curtachalasins X1–X6 (1–6), together with six known compounds (7–12) were isolated from the endophytic fungus Xylaria curta E10 harbored in the plant Solanum tuberosum.
Zhang X, Fan Y, Ye K, Pan X, Ma X, Ai H, Shi B, Liu J.   +7 more
europepmc   +2 more sources

Epigenetic Manipulation Induced Production of Immunosuppressive Chromones and Cytochalasins from the Mangrove Endophytic Fungus Phomopsis asparagi DHS-48. [PDF]

Mar Drugs, 2022
A mangrove endophytic fungus Phomopsis asparagi DHS-48 was found to be particularly productive with regard to the accumulation of substantial new compounds in our previous study.
Feng T, Wei C, Deng X, Chen D, Wen Z, Xu J.   +5 more
europepmc   +2 more sources

The Cytochalasins and Polyketides from a Mangrove Endophytic Fungus Xylaria arbuscula QYF. [PDF]

Mar Drugs
Twelve compounds, including four undescribed cytochalasins, xylariachalasins A–D (1–4), four undescribed polyketides (5–8), and four known cytochalasins (9–12), were isolated from the mangrove endophytic fungus Xylaria arbuscula QYF. Their structures and
Tan Q, Ye X, Fu S, Yin Y, Liu Y, Wu J, Cao F, Wang B, Zhu T, Yang W, She Z.   +10 more
europepmc   +2 more sources

Cytochalasins from the Ash Endophytic Fungus <i>Nemania diffusa</i> DSM 116299. [PDF]

Molecules
The secondary metabolome of Nemania diffusa, isolated as an ash endophytic fungus, was analyzed in detail. From its cultures, a previously undescribed cytochalasin 1 was isolated using preparative HPLC, together with six known congeners: 18-dehydroxy ...
Demir Ö, Schmidt K, Schulz B, Stradal TEB, Surup F.   +4 more
europepmc   +2 more sources