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The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]
Journal of Mind and Medical Sciences, 2020 Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Nicolae Bacinschi +6 more
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European Psychiatry, 2022 Introduction The anticonvulsant m-Cl-BHM is promising for the pathogenetically directed thrapy does not cause negative effects. Objectives Investigation of the effect of m-Сl-BHM on “immunochemical homeostasis” in rats with experimental alcoholism ...
Т. Shushpanova +12 more
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Pharmacogenetic Guidelines for Psychotropic Drugs: Optimizing Prescriptions in Clinical Practice
Pharmaceutics, 2023 The modalities for prescribing a psychotropic (dose and choice of molecule) are currently unsatisfactory, which can lead to a lack of efficacy of the treatment associated with prolonged exposure of the patient to the symptoms of his or her illness and ...
Antoine Baldacci +8 more
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The Arabidopsis Book, 2002 There are 272 cytochrome P450 genes (including 26 pseudogenes) in the Arabidopsis genome. P450s thus form one of the largest families of proteins in higher plants. This explosion of the P450 family is thought to have occurred via gene duplication and conversion, and to result from the need of sessile plants to adapt to a harsh environment and to ...
Danièle, Werck-Reichhart +2 more
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Frontiers in Microbiology, 2023 The recent reclassification of the strict anaerobe Geobacter sulfurreducens bacterium as aerotolerant brought attention for oxidative stress protection pathways.
Pilar C. Portela +9 more
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Frontiers in Microbiology, 2021 Integration host factor (IHF) is a widely distributed small heterodimeric protein member of the bacterial Nucleoid-Associated Proteins (NAPs), implicated in multiple DNA regulatory processes.
Angel Andrade +8 more
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The Arabidopsis Book, 2011 There are 244 cytochrome P450 genes (and 28 pseudogenes) in the Arabidopsis genome. P450s thus form one of the largest gene families in plants. Contrary to what was initially thought, this family diversification results in very limited functional redundancy and seems to mirror the complexity of plant metabolism.
Bak, Søren +6 more
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Age-related modifications in CYP-dependent drug metabolism: role of stress
Frontiers in Endocrinology, 2023 Accumulating clinical evidence indicates extensive inter-individual variations in the effectiveness and adverse effects of standard treatment protocols, which are largely attributed to the multifactorial regulation of the hepatic CYP-dependent drug ...
Maria Konstandi, Elizabeth O. Johnson
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Diagnostics, 2022 The radiothermometry (RTM) study of a cytochrome-containing system (CYP102 A1) has been conducted in order to demonstrate the applicability of RTM for monitoring changes in the functional activity of an enzyme in case of its point mutation. The study has
Yuri D. Ivanov +9 more
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Redox-Regulation of α-Globin in Vascular Physiology
Antioxidants, 2022 Interest in the structure, function, and evolutionary relations of circulating and intracellular globins dates back more than 60 years to the first determination of the three-dimensional structure of these proteins.
Laurent Kiger +7 more
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