Results 21 to 30 of about 630,553 (340)
Priapism, pomegranate juice, and sildenafil: Is there a connection?
Urology Annals, 2012 We report the development of low flow priapism in three patients related to simultaneous consumption of sildenafil with pomegranate (Punica granatum) (POM) juice.
Subramanian Senthilkumaran +3 more
doaj +1 more source
Redox-Regulation of α-Globin in Vascular Physiology
Antioxidants, 2022 Interest in the structure, function, and evolutionary relations of circulating and intracellular globins dates back more than 60 years to the first determination of the three-dimensional structure of these proteins.
Laurent Kiger +7 more
doaj +1 more source
Applied Sciences, 2019 Mycotoxins known as aflatoxins (AF) are produced as a secondary metabolite by some species of Aspergillus fungi. They are considered carcinogenic, hepatotoxic, teratogenic, and mutagenic.
Isui Abril García-Montoya +7 more
doaj +1 more source
Age-related modifications in CYP-dependent drug metabolism: role of stress
Frontiers in Endocrinology, 2023 Accumulating clinical evidence indicates extensive inter-individual variations in the effectiveness and adverse effects of standard treatment protocols, which are largely attributed to the multifactorial regulation of the hepatic CYP-dependent drug ...
Maria Konstandi, Elizabeth O. Johnson
doaj +1 more source
An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9*
Journal of Biological Chemistry, 1999 We report here the reconstitution of the de novo procaspase-9 activation pathway using highly purified cytochrome c, recombinant APAF-1, and recombinant procaspase-9. APAF-1 binds and hydrolyzes ATP or dATP to ADP or dADP, respectively. The hydrolysis of
Hua Zou +3 more
semanticscholar +1 more source
Diagnostics, 2022 The radiothermometry (RTM) study of a cytochrome-containing system (CYP102 A1) has been conducted in order to demonstrate the applicability of RTM for monitoring changes in the functional activity of an enzyme in case of its point mutation. The study has
Yuri D. Ivanov +9 more
doaj +1 more source
Mitochondrial cytochrome-b, cytochrome-c and d-loop region based phylogenetic and diversity analysis in blackbuck (antilope cervicapra) [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 The present study was designed to find diversity analysis of Antilope cervicapra family in Pakistan. Fecal samples of Antilope cervicapra were collected from their different habitats of Pakistan. Fecal DNA was extracted and Polymerase Chain Reaction (PCR)
Ghulam ABBAS +8 more
doaj +1 more source
Electrostatic interaction of cytochrome c with cytochrome c1 and cytochrome oxidase.
Journal of Biological Chemistry, 1981 The reactions of horse heart cytochrome c with succinate-cytochrome c reductase and cytochrome oxidase were studied as a function of ionic strength using both spectrophotometric and oxygen electrode assay techniques. The kinetic parameter Vmax/Km for both reactions decreased very rapidly as the ionic strength was increased, indicating that ...
Francis Millett, A J Ahmed, H T Smith
openaire +3 more sources
Mechanisms of Cytochrome P450-Catalyzed Oxidations.
ACS Catalysis, 2018 Enzymes are complex biological catalysts and are critical to life. Most oxidations of chemicals are catalyzed by cytochrome P450 (P450, CYP) enzymes, which generally utilize mixed-function oxidase stoichiometry, utilizing pyridine nucleotides as electron
F. Guengerich
semanticscholar +1 more source
Journal of Cell Biology, 1999 Exit of cytochrome c from mitochondria into the cytosol has been implicated as an important step in apoptosis. In the cytosol, cytochrome c binds to the CED-4 homologue, Apaf-1, thereby triggering Apaf-1–mediated activation of caspase-9.
E. Slee +11 more
semanticscholar +1 more source