Results 181 to 190 of about 655,985 (330)

PPP1R3B Suppresses Atherosclerosis by Promoting the M2 Polarization of Macrophages Through Glycogen Metabolic Reprogramming

Advanced Science, EarlyView.
PPP1R3B induces anti‐inflammatory M2 macrophage polarization and maintains energy supply in plaques. Its absence accelerates plaque progression. PPP1R3B regulates M2 macrophage polarization and energy metabolism via phosphorylated STAT3 (p‐STAT3), which plays a dual role by activating anti‐inflammatory transcriptional programs through the PPAR‐γ/PGC‐1α/
Lin Shen, Junchao Yu, Weiqian Chen, Yanran Bi, Zhangyu Yang, Chenying Lu, Chengli Jiang, Yang Yang, Minjiang Chen, Jianhua Zou, Lingchun Lv, Xiaoyuan Chen, Jiansong Ji   +12 more
wiley   +1 more source

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Dual‐Emission Carbon Dot Nanozymes Mitigate Salt Stress and Enhance Photosynthesis for Crop Germination and Growth

Advanced Science, EarlyView.
Dual‐emission carbon dot nanozymes are synthesized via microwave method. The nanozymes enhance photosynthesis corn seedlings through spectral‐matched light conversion. Their superoxide dismutase‐mimetic activity scavenges salt stress‐induced reactive oxygen species and circumvents energy‐intensive stress responses.
Chengfu Su, Xin Peng, Jingying Tan, Yujie Chang, Naifei Pan, Haiying Chen, Xiaokai Xu, Lei Han   +7 more
wiley   +1 more source

A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate

Advanced Science, EarlyView.
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao, Hui Zhang, Yidong Liu, Xianzhi Xu, Wei Liu, Zhaoqi Kang, Rong Xu, Shuang Hou, Ping Han, Chuanjuan Lü, Cuiqing Ma, Ping Xu, Chao Gao   +12 more
wiley   +1 more source

A Bacterial Diphosphopyridine Nucleotide-Linked Cytochrome c Reductase

, 1952
Arnold F. Brodie
openalex   +1 more source

Enzymes of cow’s and buffalo’s milk. I. Oxidation-reduction enzymes. Peroxidase, Xanthine Oxidase, Catalase and Cytochrome C reductase [PDF]

, 1969

openalex   +1 more source

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
wiley   +1 more source

COLORIMETRIC MICRODETERMINATION OF CYTOCHROME c OXIDASE

, 1954
Werner Straus
openalex   +1 more source

Novel Evolutionarily Conserved Oncogene COA4 is Driven by KRAS Mutant and Promotes Cancer Metastasis Through Dual Mitochondrial Metabolism‐Dependent and ‐Independent Mechanisms

Advanced Science, EarlyView.
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji, Weiying Zhang, Fuyuan Xue, Jiazhen Zeng, Qinghua Zhao, Xiaoming Sun, Jian Sun, Heng Zhou, Quanlin Xu, Guoyuan Ma, Shengnan Sun, Ying Wang, Qian Mu, Yi Liu, Qiang Wan   +14 more
wiley   +1 more source

Proton-linked effects on the axial coordination in ferric and ferrous horse heart cytochrome c. [PDF]

Protein Sci
Sebastiani F, Bocedi A, De Simone G, Notari S, Gambardella G, Sbardella D, Smulevich G, Ascenzi P, Coletta M.   +8 more
europepmc   +1 more source