Results 11 to 20 of about 604,858 (259)
Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1910-1917, December 2022., 2022 Abstract Objective Flail arm syndrome (FAS) is one of the atypical subtypes of amyotrophic lateral sclerosis (ALS). Mutations in hnRNPA1 encoding heterogeneous nuclear ribonucleoprotein (hnRNP) A1 are a rare genetic cause of ALS. Herein, marked clinical heterogeneity of FAS in a pedigree with a known hnRNPA1 variant was described to raise early ...
Xiaochen Han +5 more
wiley +1 more source
Physiological Reports, 2021 Skeletal muscle, a highly active tissue, makes up 40% of the total body weight. This tissue relies on mitochondria for ATP production, calcium homeostasis, and programed cell death.
Jennifer A. Wilkinson +2 more
doaj +1 more source
Electron transfer interactome of cytochrome C.
PLoS Computational Biology, 2012 Lying at the heart of many vital cellular processes such as photosynthesis and respiration, biological electron transfer (ET) is mediated by transient interactions among proteins that recognize multiple binding partners.
Alexander N Volkov, Nico A J van Nuland
doaj +1 more source
Redox Biology, 2018 In this work, we measured the effect of cytochrome c on the NADH-dependent superoxide anion production by synaptic plasma membrane vesicles from rat brain.
Alejandro K. Samhan-Arias +5 more
doaj +1 more source
Mitochondrial DNA variation in the endangered fish Dawkinsia tambraparniei (Actinopterygii: Cypriniformes: Cyprinidae) from southern Western Ghats, India [PDF]
Acta Ichthyologica et Piscatoria, 2014 Background. Dawkinsia tambraparniei (Silas, 1954) is confined to an area not exceeding 100 km2 within a single watershed—the Tamiraparani River, southern Western Ghats, India.
K. Kannan +3 more
doaj +3 more sources
mBio, 2023 Heme, an essential molecule for virtually all living organisms, acts primarily as a cofactor in a large number of proteins. However, how heme is mobilized from the site of synthesis to the locations where hemoproteins are assembled remains largely ...
Sirui Han +4 more
doaj +1 more source
Biosensors, 2023 Cytochrome c (Cytc) is a key redox protein for energy metabolism and apoptosis in cells. The activation of Cytc is composed of several steps, including its transfer to the mitochondrial membrane, binding to cytochrome c heme lyase (CCHL) and covalent ...
Mehmet Yunus Genceroglu +3 more
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Structure-Function Analysis of the Bifunctional CcsBA Heme Exporter and Cytochrome
mBio, 2018 Although intracellular heme trafficking must occur for heme protein assembly, only a few heme transporters have been unequivocally discovered and nothing is known about their structure or mechanisms.
Molly C. Sutherland +5 more
doaj +1 more source
Differentiation and cell density upregulate cytochrome c levels in megakaryoblastic cell lines: Implications for analysis of CYCS-associated thrombocytopenia. [PDF]
PLoS ONE, 2017 Mutations in the cytochrome c gene (CYCS) cause autosomal dominant thrombocytopenia by an unknown mechanism. While attempting to generate megakaryoblastic cell lines exogenously expressing cytochrome c variants, we discovered that endogenous cytochrome c
Lily Ong +2 more
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Kinetics of proton pumping in cytochrome c oxidase [PDF]
J. Chem. Phys. 130, 235105 (2009), 2008 We propose a simple model of cytochrome c oxidase, including four redox centers and four protonable sites, to study the time evolution of electrostatically coupled electron and proton transfers initiated by the injection of a single electron into the enzyme.
arxiv +1 more source