Results 251 to 260 of about 655,985 (330)

Synthesis and Application of Bioactive N‐Functionalized Aziridines

Angewandte Chemie, EarlyView.
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan, Samya Samanta, Nan Qiu, Alexander Adibekian, David C. Powers   +4 more
wiley   +2 more sources

A Case of Infantile Reversible Cytochrome C Oxidase Deficiency Myopathy in Taiwan: A 4-Year Follow-Up. [PDF]

Case Rep Med
Ma YT, Lin JL, Lai MW, Chou IJ, Hwang MS.   +4 more
europepmc   +1 more source

Identification of CO-binding modes in the Cu_B site of bovine cytochrome c oxidase by spatial mapping of binding energy. [PDF]

FEBS J
Kang J, Matsuoka T, Tateno M.
europepmc   +1 more source

Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi

Angewandte Chemie, EarlyView.
Type III polyketide synthases (T3PKSs) produce diverse compounds of ecological and clinical importance. Here, the activity of 37 fungal T3PKSs was profiled, revealing unexpected products and generating several pharmaceutical precursors. The machine learning model trained on the activity data accurately extrapolates the predictions to other enzymes and ...
Nika Sokolova, Stepan S. Denisov, Thomas Hackl, Kristina Haslinger   +3 more
wiley   +2 more sources

Electrode- and Label-Free Assessment of Electrophysiological Firing Rates through Cytochrome C Monitoring via Raman Spectroscopy. [PDF]

ACS Sens
Tentellino C, d'Amora M, Melikov R, Iachetta G, Bruno G, Tantussi F, Dipalo M, De Angelis F.   +7 more
europepmc   +1 more source

Ein neuer Malariawirkstoff hemmt die Proteinsynthese von Plasmodium falciparum

Angewandte Chemie, EarlyView.
Die Verbindung 31 stellt einen vielversprechenden Ansatz für die Entwicklung eines Malariawirkstoffs mit einem starken Wirkungsprofil dar (PfNF54 IC50 ± s.d. = 3,9 ± 0,4 nM). Sie hat einen neuartigen Wirkmechanismus, indem sie an zytosolische Ribosomen‐Untereinheiten bindet und dadurch die Proteinsynthese im Parasiten hemmt.
Patricia Bravo, Eleonora Diamanti, Mostafa M. Hamed, Lorenzo Bizzarri, Natalie Wiedemar, Armin Passecker, Nicolas M. B. Brancucci, Anna Albisetti, Christin Gumpp, Boris Illarionov, Markus Fischer, Matthias Witschel, Tobias Schehl, Hannes Hahne, Pascal Mäser, Matthias Rottmann, Anna K. H. Hirsch   +16 more
wiley   +1 more source

Investigation of the Presence of Papillomavirus in Bovine Testicles and Determination of γH2AX and Cytochrome C in Testicular Tissues Determined to be Infected. [PDF]

Vet Med Sci
Karatas O, Ozkaraca M, Atasoy MO.
europepmc   +1 more source

The Amino Acid Sequence of Wheat Germ Cytochrome c

, 1967
Frits C. Stevens, Alexander N. Glazer, Emil L. Smith   +2 more
openalex   +1 more source

Solvent Channels and Electric Fields Guide Proton Delivery to the Active Site of Heme Peroxidases

Angewandte Chemie, EarlyView.
Electrostatic potential surfaces and electric field lines reveal that local fields guide proton delivery through multiple conserved solvent channels in heme peroxidases, enabling efficient access to the active site. Abstract The active sites of heme enzymes have evolved to control the formation of highly reactive intermediates in oxidative catalysis ...
Reynier Suardíaz, Shakir Ali Siddiqui, Hanna Kwon, Marc W. van der Kamp, Lola González‐Sánchez, Peter C. E. Moody, Emma L. Raven, Adrian J. Mulholland   +7 more
wiley   +2 more sources

A high copy suppressor screen identifies factors enhancing the allotopic production of subunit II of cytochrome c oxidase. [PDF]

G3 (Bethesda)
Nieto-Panqueva F, Vázquez-Acevedo M, Barrera-Gómez DF, Gavilanes-Ruiz M, Hamel PP, González-Halphen D.   +5 more
europepmc   +1 more source