Results 41 to 50 of about 623,393 (330)

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W., Ashwell M., Beattie D. S., Beattie D. S., Brunner G., Burstone M. S., Davis K. A., Delbruck A., Fiske C. H., Folch J., Gear A. R. L., Gear A. R. L., Gear A. R. L., Gelder B. F., Gotterer G. S., Hasegawa E., Hawley E. S., Johnson A. B., Klingenberg M., Kuntzel H., Labbe R. F., Lentz P. E., Neupert W., Neupert W., Novikoff A. B., Ohnishi K., Omura T., Parsons D. F., Parsons D. F., Pette D., Pollak J. K., Pullmann M. E., Raw J., Raw J., Reith A., Schneider W. C., Schuel H., Schumacher H.-H., Sebald W., Sebald W., Seligman A. M., Sies H., Sottocasa G. L., Stoffel W., Strecker H. J., Swick R. W., Szarkowska L., Tabor C. W., Tol A., Vazquez J. J., Yonetani T.   +50 more
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NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants

Communications Biology, 2022
The DsbD protein is normally required for cytochrome c maturation (Ccm) in bacteria. With cytochrome c-rich Shewanella oneidensis as the research model, NapB, the small subunit of the nitrate reductase which is a cytochrome c per se, was found to ...
Kailun Guo, Xue Feng, Weining Sun, Sirui Han, Shihua Wu, Haichun Gao   +5 more
doaj   +1 more source

H NMR Studies of Eukaryotic Cytochrome c [PDF]

, 1982
H NMR resonance assignments in the spectra of horse, tuna, Neurmpora crassa and Candida krusei cyto-chromes c are described. Assignments have been made using NMR double-resonance techniques in conjunction with electron-exchange experiments, spectral ...
Boswell, Campbell, Carrington, Dickerson, Eley, Eley, Ernst, Hoffman, Keller, Keller, Korb, McDonald, Moore, Moore, Moore, Redfield, Stellwagen, Swanson   +17 more
core   +1 more source

CYC1 Silencing Sensitizes Osteosarcoma Cells to TRAIL-Induced Apoptosis

Cellular Physiology and Biochemistry, 2014
Aims: Osteosarcoma (OS) is an aggressive bone malignancy with poor prognosis. Many OS cells are resistant to apoptotic induction by tumor necrosis factor-related apoptosis inducing ligand (TRAIL).
Guodong Li, Dong Fu, Wenqing Liang, Lin Fan, Kai Chen, Liancheng Shan, Shuo Hu, Xiaojun Ma, Ke Zhou, Biao Cheng   +9 more
doaj   +1 more source

Confocal Raman data analysis enables identifying apoptosis of MCF-7 cells caused by anticancer drug paclitaxel [PDF]

, 2013
Confocal Raman microscopy is a noninvasive, label-free imaging technique used to study apoptosis of live MCF-7 cells. The images are based on Raman spectra of cells components, and their apoptosis is monitored through diffusion of cytochrome c in ...
Attila-Gergely Vegh, Csilla Gergely, Elodie Middendorp, Frederic Cuisinier, Hamideh Salehi, Ivan Panayotov, Pierre-Yves Collart Dutilleul, Sathish Ramakrishnan   +7 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

A Structural Model of the Cytochrome c Reductase/Oxidase Supercomplex from Yeast Mitochondria [PDF]

, 2007
Mitochondrial respiratory chain complexes are arranged in supercomplexes within the inner membrane. Interaction of cytochrome c reductase (complex III) and cytochrome c oxidase (complex IV) was investigated in Saccharomyces cerevisiae. Projection maps at
Allen, Berry, Boumans, Cruciat, DeLano, Dudkina, Dudkina, Dudkina, Dudkina, Giraud, Guex, Harris, Heinemeyer, Khalimonchuk, Kim, Lange, Lee, Ludtke, Mannella, Meisinger, Minauro-Sanmiguel, Neuhoff, Paumard, Pearce, Penczek, Pfeiffer, Roberts, Saraste, Schwerzmann, Schäfer, Schägger, Schägger, Schägger, Schägger, Stroh, Sunderhaus, Tsukihara, Van Heel, Van Heel, Wittig, Wittig, Zerbetto, Zhang, Zhang   +43 more
core   +5 more sources

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

FEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff, Dominik Trauth, Weronika Śliwińska, Linda Boss, Roland Lill   +4 more
wiley   +1 more source

The role of cytochrome c on apoptosis induced by Anagrapha falcifera multiple nuclear polyhedrosis virus in insect Spodoptera litura cells.

PLoS ONE, 2012
There are conflicting reports on the role of cytochrome c during insect apoptosis. Our previous studies have showed that cytochrome c released from the mitochondria was an early event by western blot analysis and caspase-3 activation was closely related ...
Kaiyu Liu, Duanyang Shu, Na Song, Zhongchao Gai, Yuan Yuan, Juan Li, Min Li, Shuying Guo, Jianxin Peng, Huazhu Hong   +9 more
doaj   +1 more source

Import of apocytochrome c into the mitochondrial intermembrane space along a cytochrome c1 sorting pathway [PDF]

, 1990
The question of whether cytochrome c could be functionally sorted to the mitochondrial intermembrane space along a "conservative sorting" pathway was investigated using a fusion protein termed pLc1-c. pLc1-c contains 3-fold targeting information, namely,
Neupert, Walter, Nicholson, Donald W., Stuart, Rosemary A., Wienhues, Ulla   +3 more
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