Results 41 to 50 of about 655,985 (330)
Cells, 2022 Cytochrome c (Cc) underwent accelerated evolution from the stem of the anthropoid primates to humans. Of the 11 amino acid changes that occurred from horse Cc to human Cc, five were at Cc residues near the binding site of the Cc:CcO complex. Single-point
Sue Ellen Brand +10 more
doaj +1 more source
Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells [PDF]
, 2019 In this work, we have exploited the unique properties of a chimeric archaeal-human ferritin to encapsulate, deliver and release cytochrome c and induce apoptosis in a myeloid leukemia cell line.
Baiocco, P. +8 more
core +2 more sources
ABTS oxidation reaction as a model of cytochrome c-driven electron transfer [PDF]
The Ukrainian Biochemical JournalCytochrome c, as an electron carrier within the mitochondria, plays a crucial role in the electron transport chain. To meet the demand for rapid methods that assess the electron transport properties of cytochrome c, we used the electron donor 2,2′-azino ...
F. Gudratova +4 more
doaj +1 more source
Mapping the Cytochrome C Folding Landscape [PDF]
, 2003 The solution to the riddle of how a protein folds is encoded in the conformational energy landscape for the constituent polypeptide. Employing fluorescence energy transfer kinetics, we have mapped the S.
Lyubovitsky, Julia Gennadievna
core +1 more source
Cholate Disrupts Regulatory Functions of Cytochrome c Oxidase
Cells, 2021 Cytochrome c oxidase (CytOx), the oxygen-accepting and rate-limiting enzyme of mitochondrial respiration, binds with 10 molecules of ADP, 7 of which are exchanged by ATP at high ATP/ADP-ratios.
Rabia Ramzan +4 more
doaj +1 more source
Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV [PDF]
, 2019 The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies.
Díaz Moreno, Irene +4 more
core +1 more source
Cytochrome C Oxidase Deficiency and Respiratory Distress
Pediatric Neurology Briefs, 1989 A newborn male presenting with severe respiratory insufficiency, generalized muscle weakness, and lactic acidemia is reported from the Department of Pediatrics, Nagasaki University School of Medicine, Japan.
J Gordon Millichap
doaj +1 more source
Biogenesis of mitochondrial ubiquinol [PDF]
, 1982 The precursor proteins to the subunits of ubiquinol:cytochrome c reductase (cytochrome bc1 complex) of Neurospora crassa were synthesized in a reticulocyte lysate.
Neupert, Walter +3 more
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
CYC1 Silencing Sensitizes Osteosarcoma Cells to TRAIL-Induced Apoptosis
Cellular Physiology and Biochemistry, 2014 Aims: Osteosarcoma (OS) is an aggressive bone malignancy with poor prognosis. Many OS cells are resistant to apoptotic induction by tumor necrosis factor-related apoptosis inducing ligand (TRAIL).
Guodong Li +9 more
doaj +1 more source