Results 41 to 50 of about 20,306,851 (378)
Cytochrome c (Cc) underwent accelerated evolution from the stem of the anthropoid primates to humans. Of the 11 amino acid changes that occurred from horse Cc to human Cc, five were at Cc residues near the binding site of the Cc:CcO complex. Single-point
Sue Ellen Brand+10 more
doaj +1 more source
Early steps in mitochondrial protein import [PDF]
The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Neupert, Walter+2 more
core +1 more source
The role of a disulfide bridge in the stability and folding kinetics of Arabidopsis thaliana cytochrome c6A [PDF]
Cytochrome c 6A is a eukaryotic member of the Class I cytochrome c family possessing a high structural homology with photosynthetic cytochrome c 6 from cyanobacteria, but structurally and functionally distinct through the presence of a disulfide bond and
Arslan+64 more
core +1 more source
An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9*
We report here the reconstitution of the de novo procaspase-9 activation pathway using highly purified cytochrome c, recombinant APAF-1, and recombinant procaspase-9. APAF-1 binds and hydrolyzes ATP or dATP to ADP or dADP, respectively. The hydrolysis of
Hua Zou+3 more
semanticscholar +1 more source
Assembly of Cytochrome c [PDF]
Transport of apocytochrome c across the outer mitochondrial membrane and conversion to holocytochrome c were studied in vitro. Apocytochrome c was synthesized in a cell-free homogenate from Neurospora crassa.
Hennig, Bernd, Neupert, Walter
core +2 more sources
Cytochrome C Oxidase Deficiency and Respiratory Distress
A newborn male presenting with severe respiratory insufficiency, generalized muscle weakness, and lactic acidemia is reported from the Department of Pediatrics, Nagasaki University School of Medicine, Japan.
J Gordon Millichap
doaj +1 more source
H NMR Studies of Eukaryotic Cytochrome c [PDF]
H NMR resonance assignments in the spectra of horse, tuna, Neurmpora crassa and Candida krusei cyto-chromes c are described. Assignments have been made using NMR double-resonance techniques in conjunction with electron-exchange experiments, spectral ...
Boswell+17 more
core +1 more source
Cholate Disrupts Regulatory Functions of Cytochrome c Oxidase
Cytochrome c oxidase (CytOx), the oxygen-accepting and rate-limiting enzyme of mitochondrial respiration, binds with 10 molecules of ADP, 7 of which are exchanged by ATP at high ATP/ADP-ratios.
Rabia Ramzan+4 more
doaj +1 more source
Cytochrome c as a Potentially Clinical Useful Marker of Mitochondrial and Cellular Damage
Mitochondria are evolutionary endosymbionts derived from bacteria. Thus, they bear molecules, such as mitochondrial DNA (mtDNA) that contains CpG DNA repeats and N-formyl peptides (FPs), found in bacteria. Upon cell necrosis or apoptosis, these molecules
T. Eleftheriadis+3 more
semanticscholar +1 more source
The complex of cytochrome c and cytochrome c peroxidase: The end of the road?
Cytochrome c (Cc) and cytochrome c peroxidase (CcP) form a physiological complex in the inter-membrane space of yeast mitochondria, where CcP reduces hydrogen peroxide to water using the electrons provided by ferrous Cc. The Cc-CcP system has been a popular choice of study of interprotein biological electron transfer (ET) and in understanding dynamics ...
Volkov, A.N.+2 more
openaire +4 more sources