Results 171 to 180 of about 287,119 (261)

Silymarin attenuates oxidative, inflammatory and apoptotic damage induced by a fungicide mixture in rat liver, kidney and brain. [PDF]

Toxicol Rep
Salem HS, Gouda AMR, Essam NM, El-Bahnasy HT.   +3 more
europepmc   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Exendin-4 protects brain endothelial cell damage against hyperammonemic condition. [PDF]

Biochem Biophys Rep
Ahn SY, Jo D, Choi SY, Song J.
europepmc   +1 more source

Isosteric Engineering of Enzymes: Overcoming Activity–Stability Trade‐Offs by Site‐Selective CH → N Substitutions

Angewandte Chemie, EarlyView.
Coupling biosynthetic noncanonical amino acid production with genetic code expansion enables site‐specific incorporation of azatryptophans into PET‐degrading enzymes (PETases). By isosteric single‐atom editing of a conserved tryptophan, AzaPETases break the activity–stability trade‐off, delivering higher catalytic efficiency at elevated temperature and
Elwy H. Abdelkader, Haocheng Qianzhu, Gottfried Otting, Thomas Huber   +3 more
wiley   +2 more sources

The role of Zearalenone in epigenetic modifications of candidate genes in Nellore heifers. [PDF]

Trop Anim Health Prod
Coelho LADS, Barbero RP, Pereira PRMT, Polido CEB, de Aguiar ACSR, Santos HA, de Mello MRB, Kern EL, Andia DC, Barbero MMD.   +9 more
europepmc   +1 more source

Aggregation of Phosphates Enhances Enzyme Activity in Aqueous Solution. [PDF]

Chemphyschem
Bajpayee S, Murugan V, Price WS, Rana S, Beves JE.   +4 more
europepmc   +1 more source

Development and Validation of a Quantitative LC-MS/MS Method for Measuring CYP4V2 Enzyme Activity via 12-Hydroxylauric Acid in rAAV-hCYP4V2 Gene Therapy Products. [PDF]

Molecules
Ren G, Qin X, Li Y, Fan W, Luo W, Cao Y, Wang Y, Zhou Y, Liang C.   +8 more
europepmc   +1 more source

<i>SfCYP6AN4</i>-Mediated Spinetoram Resistance and RNA Pesticide Application in <i>Spodoptera frugiperda</i>. [PDF]

Insects
Yuan L, Yu D, Wang J, Li Y, Dai Y, Xiao H, Zhang Z.   +6 more
europepmc   +1 more source

Cytochrome c as a central regulator of mitochondrial function in cancer metabolism. [PDF]

Discov Oncol
Shabir A, Sofi S, Jan N, Haq BU, Qayoom H, Mir MA.   +5 more
europepmc   +1 more source

Integrated analysis of metabolome and transcriptome reveals the mechanism of divergent acute heat stress responses in mango cultivars. [PDF]

Front Plant Sci
Luo W, Hou X, Wei L, Liu S, Li R, Teng Z, Yang C, Li Y, Zhu Z.   +8 more
europepmc   +1 more source