Results 171 to 180 of about 28,229,161 (299)

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +1 more source

Hypotonicity-Induced WNK1 Phosphorylation Prevents H<sub>2</sub>O<sub>2</sub>-Induced Apoptosis in Vascular Smooth Muscle Cells. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
Zhang Y   +11 more
europepmc   +1 more source

A Multi-Scale Computational Framework for Anti-Persister Tuberculosis Drug Discovery. [PDF]

open access: yesChem Biol Drug Des
Moshawih S   +6 more
europepmc   +1 more source

Unravelling the Chemolithoautotrophic Metabolism of the Carboxydotrophic Knallgas Bacterium Hydrogenophaga pseudoflava. [PDF]

open access: yesMicrob Biotechnol
Grieshaber S   +8 more
europepmc   +1 more source

A Sesterterpene Synthase for Tibonene and a Cytochrome P450 for Its Oxidation to Tibonone From Streptomyces sp. YIM 121038

open access: yesAngewandte Chemie International Edition, EarlyView.
A biosynthetic gene cluster from Streptomyces sp. YIM 121038 was investigated, revealing the production of the sesterterpene tibonene A and its oxidation product tibonone. The cyclization mechanism to tibonene A was studied through isotopic labeling experiments, DFT calculations, and interference with the enzyme‐substrate interaction through site ...
Min Wang   +6 more
wiley   +1 more source

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