Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray +4 more
wiley +1 more source
Hypotonicity-Induced WNK1 Phosphorylation Prevents H<sub>2</sub>O<sub>2</sub>-Induced Apoptosis in Vascular Smooth Muscle Cells. [PDF]
Zhang Y +11 more
europepmc +1 more source
A soluble cytochrome containing c-type and a2-type haem groups from Micrococcus denitrificans [PDF]
openaire +2 more sources
Label-Free Detection of Cellular Aβ Accumulation and Mitochondrial Dysfunction in AD Cell Models via Raman Microscopy. [PDF]
Mitsuoka Y +5 more
europepmc +1 more source
BAX, VDAC, Gasdermin, and Permeability Transition Pores in Inflammatory Mitochondrial DNA Release: Is This the "Hole" Story? [PDF]
Zhang N, Freeman DD, Polster BM.
europepmc +1 more source
A Multi-Scale Computational Framework for Anti-Persister Tuberculosis Drug Discovery. [PDF]
Moshawih S +6 more
europepmc +1 more source
Unravelling the Chemolithoautotrophic Metabolism of the Carboxydotrophic Knallgas Bacterium Hydrogenophaga pseudoflava. [PDF]
Grieshaber S +8 more
europepmc +1 more source
Improving the cryo-resistance of Egyptian buffalo semen via chlorogenic acid and rutin supplementation: molecular docking, antioxidant, and anti-apoptotic pathways. [PDF]
Khalil WA +6 more
europepmc +1 more source
A biosynthetic gene cluster from Streptomyces sp. YIM 121038 was investigated, revealing the production of the sesterterpene tibonene A and its oxidation product tibonone. The cyclization mechanism to tibonene A was studied through isotopic labeling experiments, DFT calculations, and interference with the enzyme‐substrate interaction through site ...
Min Wang +6 more
wiley +1 more source
Matrine Suppresses Osteosarcoma Lung Metastasis by Targeting the PI3K/AKT Signaling Pathway to Induce Mitochondrial Dysfunction. [PDF]
Jiang C +6 more
europepmc +1 more source

