Results 261 to 270 of about 2,436,389 (378)

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Polydatin upregulates ZDHHC19 to promote apoptosis of acute myeloid leukemia cells via mediating BID palmitoylation. [PDF]

Cell Commun Signal
Zhang W, Liu Z, Pei X, Hao P, Jiang L, Shi M, Yuan X, Zhu Z.   +7 more
europepmc   +1 more source

A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani, Elena Valdés, José María Miralles‐Robledillo, Guillermo Martínez, Carmen Pire, Rosa María Martínez‐Espinosa   +5 more
wiley   +1 more source

Whole-Genome Analysis and Lignin Degradation Characterization of Termite-Derived <i>Bacillus cereus</i> BC-8. [PDF]

Microorganisms
Zhang X, Li J, Hu Y, Cai Z, Li N, Xue R, Mo Z, Yang C, Yang Y.   +8 more
europepmc   +1 more source

Transient Transfection of Rolling‐Circle Amplified DNA in Biomanufacturing‐Relevant Mammalian Cell Lines: A Comparison of Transfection Conditions for Optimal Protein Expression

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Rolling‐circle amplification (RCA) is a completely synthetic and rapid mechanism for scaling‐up bulk DNA that eliminates requirements for large‐scale bacterial fermentation. Several reports have described the surprising ability of large unprocessed (hyperbranched) rolling circle‐amplified DNA (RCA DNA) to effectively transfect cultured cells ...
Evelina Loghin, Erik Kvam, Lisa Lowery, Nathan Hudson, Jenny Keen, Brian Davis, Roger B. Dodd, Christine Surrette, John Nelson   +8 more
wiley   +1 more source

Enzyme engineering of cytochrome P450 RosC provides mechanistic insights into factors controlling iterative oxidation. [PDF]

Appl Microbiol Biotechnol
Iizaka Y, Suzuki H, Sasa N, Ishiuchi K, Kumakiri Y, Kawasaki H, Sato H, Fujimoto K, Noguchi S, Anzai Y.   +9 more
europepmc   +1 more source

Increasing the succinate yield in Actinobacillus succinogenes by fumigation of H2 in a bioreactor

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The microbial conversion of CO2 into value‐added chemicals offers a promising and scalable route for sustainable bioproduction, particularly under mild reaction conditions and with technically straightforward reactor configurations. Actinobacillus succinogenes, a natural succinate producer, can fix CO2 through anaplerotic carboxylation but its
Julian Tix, Gustav Zimpel, Roland Ulber, Nils Tippkötter   +3 more
wiley   +1 more source

Modulation of human neutrophil functions by hydroethanolic cladode extract of Opuntia ficus-indica: an in vitro experimental study. [PDF]

BMC Complement Med Ther
Ferjani W, Dang PM, Fetoui H, Bedouhene S, Kouki A, Ben-Attia M, El-Benna J, Souli A.   +7 more
europepmc   +1 more source

Studies on cytochrome c peroxidase. XII. Crystalline synthetic enzymes containing unnatural heme prosthetic groups.

The Journal of biological chemistry, 1968
T, Yonetani, T, Asakura
openaire   +1 more source