Results 51 to 60 of about 28,229,161 (299)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Biogenesis of cytochrome c1 [PDF]

, 1989
The biogenesis of cytochrome c1 involves a number of steps including: synthesis as a precursor with a bipartite signal sequence, transfer across the outer and inner mitochondrial membranes, removal of the first part of the presequence in the matrix ...
Stuart, Rosemary A., Neupert, Walter, Nicholson, Donald W.   +2 more
core   +1 more source

Suitability of Adenosine Derivatives in Improving the Activity and Stability of Cytochrome c under Stress: Insights into the Effect of Phosphate Groups

The Journal of Physical Chemistry B, 2023
It is well known that adenosine and its phosphate derivatives play a crucial role in biological phenomena such as apoptosis and cell signaling and act as the energy currency of the cell. Although their interactions with various proteins and enzymes have been described, the focus of this work is to demonstrate the effect of the phosphate group on the ...
Bharadwaj, Pranav, Shet, Sachin, BISHT, MEENA, Sarkar, Dheeraj Kumar, Gregory, Franklin, Sanna Kotrappanavar, Nataraj, Mondal, Dibyendu   +6 more
openaire   +2 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Western blot detection and quantification of cytochrome c protein in mitochondrial and cytosolic fractions of the Saline group and the Polymyxin B group.

, 2016
Western blot detection and quantification of cytochrome c protein in mitochondrial and cytosolic fractions of the Saline group and the Polymyxin B group.
Edson Andrade Pessoa (2993853), Luciana Barros de Moura Neiva (2993850), Maria de Fátima Fernandes Vattimo (2993844), Cassiane Dezoti da Fonseca (2993841), Fernanda Teixeira Borges (2993838), Mirian Watanabe (2993847)   +5 more
core   +1 more source

Yeast cytochrome c peroxidase. Coordination and spin states of heme prosthetic group.

Journal of Biological Chemistry, 1987
Electronic absorption and electron paramagnetic resonance (EPR) spectroscopic examinations revealed that a freshly prepared cytochrome c peroxidase (CCP) contains a penta-coordinated high spin ferric protoheme group. The penta-coordinated high spin state of fresh CCP is maintained in a remarkably wide range of pH (4-8).
T, Yonetani, H, Anni
openaire   +2 more sources

Molecular dynamics simulations and hydrogen-bonded network dynamics of cytochrome c oxidase from Paracoccus denitrificans [PDF]

, 2004
Cytochrome c oxidase is the terminal enzyme in the respiratory chain of mitochondria and aerobic bacteria. This enzyme ultimately couples electron transfer from cytochrome c to an oxygen molecule with proton translocation across the inner mitochondrial ...
Olkhova, E., Olkhova, Elena
core  

Functional interference (crosstalk) between gut microbiome, proteolysis, apoptosis and muscle hypertrophy: Role of resistance training and supplement [PDF]

Journal of Exercise & Organ Cross Talk
Primary objective of this study was to examine the interplay between grip strength, a functional marker of hypertrophy, and its connection to the Firmicutes to Bacteroidetes ratio in the gut microbiome. Twenty-five male Wistar rats were divided into five
Mona Nouri, Hamid Arazi
doaj   +1 more source

Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome-c-Oxidase in Traumatic Brain Injury Patients during Hypercapnoea A Broadband NIRS Study [PDF]

, 2011
Using broadband near-infrared spectroscopy (NIRS) and cerebral micro-dialysis (MD), we investigated cerebral cellular metabolism and mitochondrial redox states, following hypercapnoea in 6 patients with traumatic brain injury (TBI).
Tachtsidis, I, Ghosh, A, Tisdall, MM, Elwell, CE, Pritchard, C, Leung, TS, Smith, M   +6 more
core  

Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group [PDF]

ACS Chemical Biology, 2019
ABSTRACT Pentamycin is a polyene antibiotic, registered in Switzerland for the treatment of vaginal candidiasis, trichomo-niasis and mixed infections. Chemical instability has hindered its wide-spread application and development as a drug. Here we report the identification of Streptomyces
Zhou, Shanshan, Song, Lijiang, Masschelein, Joleen, Sumang, Felaine A.M., Papa, Irene A., Zulajbar, Teofila O., Custodio, Aileen B., Zabala, Daniel, Alcantara, Edwin P., de los Santos, Emmanuel L.C., Challis, Gregory L.   +10 more
openaire   +4 more sources