Results 71 to 80 of about 293,473 (312)

Scanning Electrochemical Microscopy of Cytochrome c Peroxidase through the Orientation-Controlled Immobilisation of Cytochrome c

, 2016
Immobilisation of enzymes onto surfaces with defined orientation is of particular importance in order to optimise their activity and capacity to dock electron-transfer partners.
Marquis, CP ; https://orcid.org/, Gunawan, CA, Gooding, JJ ; https://orcid.org/, Zhao, C ; https://orcid.org/, Thordarson, P ; https://orcid.org/, Nam, EV   +5 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Molecular phylogenetic relationship of the subfamily Nymphalinae (Lepidoptera: Nymphalidae) in Myanmar, inferred from mitochondrial gene sequences

Journal of Asia-Pacific Biodiversity, 2017
Phylogenetic relationships for 19 species of the subfamily Nymphalinae were inferred using 607 bp of cytochrome oxidase subunit I. The average base composition of cytochrome oxidase subunit I sequences was 37.9% T, 15.7% C, 31.5% A, and 14.9% G, showing ...
Nan Zarchi Win, Eun Young Choi, Jinyoung Park, Jong Kyun Park   +3 more
doaj   +1 more source

Molecular dynamics simulations and hydrogen-bonded network dynamics of cytochrome c oxidase from Paracoccus denitrificans

, 2004
Cytochrome c oxidase is the terminal enzyme in the respiratory chain of mitochondria and aerobic bacteria. This enzyme ultimately couples electron transfer from cytochrome c to an oxygen molecule with proton translocation across the inner mitochondrial ...
Olkhova, E., Olkhova, Elena
core  

The 1.6 Angstrom X-ray structure of the unusual c-type cytochrome, cytochrome c(L), from the methylotrophic bacterium Methylobacterium extorquens

, 2006
The structure of cytochrome c(L) from Methylobacterium extorquens has been determined by X-ray crystallography to a resolution of 1.6 Angstrom. This unusually large, acidic cytochrome is the physiological electron acceptor for the quinoprotein methanol ...
Gill, R., Mohammed, F., Cooper, Jonathan B., Mohammed, Fiyaz, Williams, P., Anthony, Chris, Wood, S.P., Williams, Paul, Coates, L., Coates, Leighton, Erskine, P., Cooper, J.B., Wood, Steve P., Anthony, C., Gill, Raj, Erskine, Peter, Bourgeois, Dominique, Bourgeois, D.   +17 more
core   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11

, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Morio Yamada, Eiichi Akaho, Hamed I. Ali, Hukihisa Fujita   +3 more
core  

Design of a Ruthenium-Cytochrome c Derivative to Measure Electron Transfer to the Initial Acceptor in Cytochrome c Oxidase

, 1995
A ruthenium-labeled cytochrome c derivative was prepared to meet two design criteria: the ruthenium group must transfer an electron rapidly to the heme group, but not alter the interaction with cytochrome c oxidase.
Beasley, James R., Saunders, Aleister J., Geren, Lois M., Hibdon, Sharon, Fine, Bryan R., Millett, Francis, Durham, Bill, Pielak, Gary J.   +7 more
core   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

Assignment of the CO-sensitive carboxyl group in mitochondrial forms of cytochrome c oxidase using yeast mutants

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2012
Point mutations of E243D and I67N were introduced into subunit I of a 6histidine-tagged (6H-WT) form of yeast Saccharomyces cerevisiae mitochondrial cytochrome c oxidase. The two mutants (6H-E243D(I) and 6H-I67N(I)) were purified and showed ≈50 and 10% of the 6H-WT turnover number. Light-induced CO photolysis FTIR difference spectra of the 6H-WT showed
Maréchal, A, Meunier, B, Rich, PR
openaire   +3 more sources