Results 121 to 130 of about 541,087 (354)

Inaccurately assembled cytochrome c oxidase can lead to oxidative stress-induced growth arrest.

open access: yesAntioxidants and Redox Signaling, 2013
AIMS To identify yeast mutants that show a strong redox dependence of the ability to respire, we systematically screened a yeast deletion library for mutants that require the presence of reductants for growth on nonfermentable carbon sources.
Manuela Bode   +6 more
semanticscholar   +1 more source

Proteogenomic characterization of cholangiocarcinoma

open access: yesHepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng   +18 more
wiley   +1 more source

Vibrational energy relaxation (VER) of a CD stretching mode in cytochrome c [PDF]

open access: yesarXiv, 2004
We first review how to determine the rate of vibrational energy relaxation (VER) using perturbation theory. We then apply those theoretical results to the problem of VER of a CD stretching mode in the protein cytochrome c. We model cytochrome c in vacuum as a normal mode system with the lowest-order anharmonic coupling elements. We find that, for the ``
arxiv  

hCOA3 Stabilizes Cytochrome c Oxidase 1 (COX1) and Promotes Cytochrome c Oxidase Assembly in Human Mitochondria*

open access: yesJournal of Biological Chemistry, 2013
Background: Assembly of cytochrome c oxidase (COX), complex IV of the respiratory chain, requires a great number of accessory proteins known as assembly factors.
P. Clemente   +7 more
semanticscholar   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Probing brain oxygenation with near infrared spectroscopy [PDF]

open access: yesNeuroQuantology |June 2009 |Vol 7 |Issue 2 |Page 258-266, 2011
The fundamentals of near infrared spectroscopy (NIRS) are reviewed. This technique allows to measure the oxygenation of the brain tissue. The particular problems involved in detecting regional brain oxygenation (rSO2) are discussed. The dominant chromophore (light absorber) in tissue is water.
arxiv  

A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase

open access: yesMolecular Biology of the Cell, 2013
The biogenesis of Cox4 is unknown. Cox4, mtHsp70, and Mge1 form a complex that promotes the assembly of cytochrome c oxidase. In the absence of the mature cytochrome c oxidase, Cox4 arrests at the chaperone complex.
L. Böttinger   +8 more
semanticscholar   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

open access: yesHepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro   +14 more
wiley   +1 more source

Mitochondrial CO1 genetic structure among breeding sites of Chinese egret (Egretta eulophotes) in South Korea

open access: yesJournal of Asia-Pacific Biodiversity, 2018
Chinese egret (Egretta eulophotes) is classified as an endangered species (VU, vulnerable) and is limited to Far East. This species breeds especially offshore in China, Russia, and the Korean peninsula.
Bo-Yeon Hwang   +4 more
doaj  

CYCLOPHOSPHAMIDE HEPATOTOXICITY: THE ROLE OF 4-HYDROXYNONENAL AND CYTOCHROME C OXIDASE AND THE POSSIBLE PROTECTIVE EFFECT OF GANODERMA LUCIDUM EXTRACT

open access: yesSlovenian Veterinary Research, 2019
Cyclophosphamide (CPA) is a widely used anti-neoplastic drug, but its usage is associated with several side effects including hepatotoxicity. This study was designed to evaluate the ameliorative effect of Ganoderma lucidium (GL) extract as a natural ...
Dina R Gad El-Karim, Gamal El-Amrawi
doaj   +1 more source

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