Results 151 to 160 of about 396,597 (394)

Solvent Channels and Electric Fields Guide Proton Delivery to the Active Site of Heme Peroxidases

Angewandte Chemie, EarlyView.
Electrostatic potential surfaces and electric field lines reveal that local fields guide proton delivery through multiple conserved solvent channels in heme peroxidases, enabling efficient access to the active site. Abstract The active sites of heme enzymes have evolved to control the formation of highly reactive intermediates in oxidative catalysis ...
Reynier Suardíaz, Shakir Ali Siddiqui, Hanna Kwon, Marc W. van der Kamp, Lola González‐Sánchez, Peter C. E. Moody, Emma L. Raven, Adrian J. Mulholland   +7 more
wiley   +2 more sources

Mitochondrial Outer Membrane Permeability Change and Hypersensitivity to Digitonin Early in Staurosporine-induced Apoptosis [PDF]

, 2003
We have shown here that the apoptosis inducer staurosporine causes an early decrease in the endogenous respiration rate in intact 143B.TK- cells. On the other hand, the activity of cytochrome c oxidase is unchanged for the first 8 h after staurosporine ...
Attardi, Giuseppe, Chomyn, Anne, Duan, Shili, Hájek, Petr, Lin, Catherine, Shin, Soo Kyung   +5 more
core  

Light Metabolically Reprograms CD8+ T Cells to Potentiate STING‐Driven Tumor Eradication and Prevent Metastasis

Advanced Science, EarlyView.
Low‐level light (LLL) rejuvenates exhausted CD8+ T cells, boosting STING‐driven tumor eradication and prevents metastasis. NanoSTING@Mn enhances CD8+ T cells infiltration while LLL restores its function expanding to progenitor‐exhausted cells. These cells form central memory T cells in lymphoid organs. Intranasal nanoSTING@Mn redirects antitumor CD8+ T
Asmita Banstola, Shilin Gao, Zhengkung Zhang, Yan Dong, Prabhat Upadhyay, Quanwei Zhang, Yongli Li, Zuan‐Tao Lin, Zhilong Wang, Mei X. Wu   +9 more
wiley   +1 more source

Enzyme Immobilization by Hydrogen‐Bonded Organic Framework for the Construction of Plant‐Wearable Sensor

Advanced Science, EarlyView.
By modulating the charge of acetylcholinesterase, it is encapsulated within HOF materials, thereby enhancing its stability and maintaining its activity. Subsequently, the composite material is embedded in a glycerol‐sodium alginate gel, achieving the long‐term monitoring of pesticides.
Hongxia Li, Xiangyu Liu, Changshun Su, Xiaoguang Zhang, Chunyan Sun, Xu Yan   +5 more
wiley   +1 more source

PURIFICATION OF CYTOCHROME c OXIDASE [PDF]

Journal of Biological Chemistry, 1954
Lucile Smith, Elmer Stotz
openaire   +2 more sources

Lignin as a Renewable Precursor for Carbon Quantum Dots: Synthesis, Doping Strategies, and Applications

Advanced Energy and Sustainability Research, EarlyView.
Lignin‐derived carbon quantum dots are produced via hydrothermal doping with ethylenediamine, enhancing fluorescence, quantum yield, and tunable photoluminescence for diverse applications. These biocompatible nanomaterials enable safe use in bioimaging, sensing, and monitoring, offering optical stability under various conditions. Valorizing lignin from
Rosinaldo Rabelo Aparício, Fabricio Augusto Hansel, Tawani Lorena Naide Acosta, Marco Antônio Schiavon, Graciela Ines Bolzon de Muniz, Washington Luiz Esteves Magalhães, Pedro Henrique Gonzalez de Cademartori   +6 more
wiley   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

The electron distribution in the “activated” state of cytochrome c oxidase

Scientific Reports, 2018
Cytochrome c oxidase catalyzes reduction of O2 to H2O at a catalytic site that is composed of a copper ion and heme group. The reaction is linked to translocation of four protons across the membrane for each O2 reduced to water.
Jóhanna Vilhjálmsdóttir, Robert B. Gennis, Peter Brzezinski   +2 more
doaj   +1 more source

Investigation of in vivo measurement of cerebral cytochrome-c-oxidase redox changes using near-infrared spectroscopy in patients with orthostatic hypotension [PDF]

, 2007
We have previously used a continuous four wavelength near infrared spectrometer to measure changes in the cerebral concentrations of oxy- (Δ[HbO2] and deoxy- haemoglobin (Δ[HHb]) during head-up tilt in patients with primary autonomic failure.
Cooper, C.E., Delpy, D.T., Elwell, C.E., Leung, T.S., Smith, M., Tachtsidis, I., Tisdall, M.   +6 more
core  

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source