Results 91 to 100 of about 4,935 (109)

Major bleeding during combined treatment with indomethacin and low doses of acenocoumarol in a homozygous patient for 2C9*3 variant of cytochrome P-450 CYP2C9

Thrombosis and Haemostasis, 2003
Major bleeding during combined treatment with indomethacin and low doses of acenocoumarol in a homozygous patient for 2C9*3 variant of cytochrome P-450 CYP2C9 -
JOSÉ Hermida, Ramon Montes
exaly   +2 more sources

Effect of different genetics variants: CYP2C9*2, CYP2C9*3 of cytochrome P-450 CYP2C9 and 1639G>A of the VKORC1 gene; On acenocoumarol requirement in Moroccan patients

Pathologie Biologie, 2013
Coumarin derivatives such as acenocoumarol represent the therapy of choice for the long-term treatment and prevention of thromboembolic diseases. Many genetics determinants involved in the metabolism of acenocoumarol have been shown to influence the anticoagulant dosage.
F Z, Smires, R, Habbal, C, Moreau, A, Assaidi, M A, Loriot, S, Nadifi   +5 more
openaire   +2 more sources

Prevalence of cytochrome P-450 2C9 (CYP2C9) alleles *2, and*3 among the Libyan population of Tripoli region

Khalij-Libya Journal of Dental and Medical Research
CYP2C9 gene encodes an enzyme that metabolizes a variety of drugs. Genetic variations in the CYP2C9 enzyme, particularly the CYP2C9*2 and CYP2C9*3 polymorphisms, can significantly impact enzyme activity, resulting in variations in drug metabolism and response among individuals who carry them.
openaire   +1 more source

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

Lancet, The, 1999
Ann Daly, Guruprasad Aithal, Christopher P Day   +2 more
exaly  

Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

British Journal of Clinical Pharmacology, 1999
Muradiye Nacak, Ivar Roots, C Sachse
exaly  

Electrochemical characterisation of the human cytochrome P450 CYP2C9

Biochemical Pharmacology, 2005
John Miners, Benjamin Lewis, L L Martin   +2 more
exaly  

Interaction of Modified Cyclodextrins with Cytochrome P-450

Bioscience, Biotechnology and Biochemistry, 2005
Hidefumi Yoshii, Furuta Takeshi, Yoshii Hidefumi   +2 more
exaly  

Esophageal cancer proliferation is mediated by cytochrome P450 2C9 (CYP2C9)

Prostaglandins and Other Lipid Mediators, 2011
Jan Schulte Am Esch, Levent Dizdar, Claus F Eisenberger   +2 more
exaly  

CYP2C9, CYP2C19, and ABCB1 Genotype and Hospitalization for Phenytoin Toxicity

Journal of Clinical Pharmacology, 2009
, Charles Leonard
exaly  

CYP2C9 allelic variants: ethnic distribution and functional significance

Advanced Drug Delivery Reviews, 2002
Richard Kim, , C Michael Stein
exaly