Results 71 to 80 of about 4,935 (109)

Comparative analysis of sex-based, vendor-based, and species differences in cytochrome P450 metabolism. [PDF]

Sci Rep
Kinatukara N, Xu X, Shah P.
europepmc   +1 more source

Herb-drug interaction of Astragali Radix based on in vitro incubation and pharmacokinetic assessment. [PDF]

BMC Complement Med Ther
Wang T, Zhang T, Chen X, Huang C, Tu P, Wang K, Qiu F.   +6 more
europepmc   +1 more source

The novel third-generation antipsychotic drug brexpiprazole affects hepatic transcription factors, serum hormone levels, and cytochrome P450 enzymes after prolonged treatment: pharmacological significance. [PDF]

Pharmacol Rep
Danek PJ, Pukło R, Daniel WA.
europepmc   +1 more source

Overlooked aspects of scaling enzyme activity through abundance across tissues and individuals: Insights from k_cat measurements in matched liver and intestinal samples. [PDF]

Drug Metab Dispos
Al-Majdoub ZM, Barber J, Rostami-Hodjegan A, Galetin A, Scotcher D.   +4 more
europepmc   +1 more source

Knockdown of RNA editing proteins reshapes the HepaRG transcriptome and pharmacogene expression. [PDF]

Sci Rep
Collins JM, Yu F, Zhang Y, Wang D.
europepmc   +1 more source

From Genotype to Functional Risk: A Multi-Omic Approach to Predicting Thiopurine and Methotrexate Co-Therapy-Induced Liver Injury. [PDF]

Pharmaceuticals (Basel)
Molnár D, Reznik E, Porrogi P.
europepmc   +1 more source

Drug-Metabolizing Enzymes in Human Keratinocytes and In Vitro Detection of Cytochrome P450-Mediated Phenolic Lamotrigine Metabolite. [PDF]

Chem Res Toxicol
Deck PN, Müller M, Glässner A, Vogel M, Steffens M, Heubach C, Fechner G, Becker K, Weindl G, Sachs B.   +9 more
europepmc   +1 more source

The Genetic Polymorphisms of CYP2C9 and VKORC1 in the Saudi Population and Their Impact on Anticoagulant Management. [PDF]

Medicina (Kaunas)
Al Hamad M.
europepmc   +1 more source

Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery. [PDF]

Proc Natl Acad Sci U S A
Davey SD, Forde-Thomas JE, Hulme BJ, Lees K, Costain AH, Evans M, Rinaldi G, Frame L, Stojanovski L, Simeons FRC, Tavendale A, MacLeod AK, Pichon R, Lee YH, Polak O, Chalmers IW, Dankwa B, Odhiambo BK, Guimaraes VH, Hegarty M, Swain MT, Aubrey W, Caldwell N, MacDonald AS, Gilbert IH, Baragaña B, Read KD, Hoffmann KF.   +27 more
europepmc   +1 more source

Confounding Effect of Hepatic Carboxylesterase 1 (CES1) Variability on Clopidogrel Oxidation. [PDF]

Mol Pharm
Subash S, Singh DK, Khojasteh SC, Murray BP, Zientek MA, Jones RS, Kulkarni P, Smith BJ, Prasad B.   +8 more
europepmc   +1 more source