Results 51 to 60 of about 4,757 (93)

Inhibitory effects of Δ8-tetrahydrocannabinol on major hepatic cytochrome P450 enzymes and implications for drug disposition. [PDF]

Drug Metab Dispos
Zhao M, Coates S, Bardhi K, Lazarus P.
europepmc   +1 more source

The Genetic Polymorphisms of CYP2C9 and VKORC1 in the Saudi Population and Their Impact on Anticoagulant Management. [PDF]

Medicina (Kaunas)
Al Hamad M.
europepmc   +1 more source

Confounding Effect of Hepatic Carboxylesterase 1 (CES1) Variability on Clopidogrel Oxidation. [PDF]

Mol Pharm
Subash S, Singh DK, Khojasteh SC, Murray BP, Zientek MA, Jones RS, Kulkarni P, Smith BJ, Prasad B.   +8 more
europepmc   +1 more source

Empirical Drug Dosage Validates Pharmacogenomic Associations in All of Us. [PDF]

Clin Transl Sci
Matthias J, Falaguera MJ, Altman RB.
europepmc   +1 more source

In vitro and clinical data demonstrate negligible risk of drug-drug interactions with opelconazole, a novel inhaled antifungal agent. [PDF]

J Antimicrob Chemother
Cass LMR, Ayrton J, Brüggemann RJ, Moore J, Martin U, Grey L, Hyman M, Berman L.   +7 more
europepmc   +1 more source

<i>CYP2C9</i> polymorphism is associated with susceptibility to ischemic stroke in a Chinese population. [PDF]

Ann Med
Zhang J, Jia H, Liu Y, Zhang Y, Nie H, Bao Q.   +5 more
europepmc   +1 more source

Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs. [PDF]

Drug Metab Dispos
Kapelyukh Y, Gabel-Jensen C, MacLeod AK, Daniel Coquelin KS, Stojanovski L, Frame L, Tavendale A, Henderson CJ, Read KD, Wolf CR, Säll C.   +10 more
europepmc   +1 more source

Expression and function of CYP enzymes and hepatobiliary transporters in an improved long-term sandwich culture hepatocyte model. [PDF]

Sci Rep
Pacsuta J, Bárány N, Kiszelák K, Csíkvári O, Mártonné Tóth B, Jemnitz K, Gáborik Z.   +6 more
europepmc   +1 more source

Binding Site Vectors Enable Mapping of Cytochrome P450 Functional Landscapes. [PDF]

J Chem Inf Model
Kuvek T, Jandová Z, Schleifer KJ, Oostenbrink C.   +3 more
europepmc   +1 more source

Genome edited intestine liver on a chip system for integrated intestinal hepatic drug absorption and metabolism evaluation. [PDF]

Sci Rep
Negoro R, Deguchi S, Yamazaki D, Takayama K, Fujita T.   +4 more
europepmc   +1 more source